Shiv Kumar Sarin, Ashish Kumar, John Almeida, Yogesh Chawla et al.
The Asian Pacific Association for the Study of the Liver (APASL) set up a working party on acute-on-chronic liver failure (ACLF) in 2004, with a mandate to develop consensus guidelines on various aspects of ACLF relevant to disease patterns and clinical practice in the Asia-Pacific region. Experts p...
Maarten Lupker, Christian France‐Lanord, Valier Galy, Jérôme Lavé et al.
Minxian Wang, Ramesh Menon, Sanghamitra Mishra, Aniruddh P. Patel et al.
Background: Genome-wide polygenic scores (GPS) integrate information from many common DNA variants into a single number. Because rates of coronary artery disease (CAD) are substantially higher among South Asians, a GPS to identify high-risk individuals may be particularly useful in this population. ...
Fyezah Jehan, Sunil Sazawal, Abdullah H Baqui, Muhammad Imran Nisar et al.
Importance: Worldwide, preterm birth (PTB) is the single largest cause of deaths in the perinatal and neonatal period and is associated with increased morbidity in young children. The cause of PTB is multifactorial, and the development of generalizable biological models may enable early detection an...
Yogendra Singh, Gaurav Gupta, Birendra Shrivastava, Rajiv Dahiya et al.
Summary Alzheimer's disease ( AD ) is leading cause of death among older characterized by neurofibrillary tangles, oxidative stress, progressive neuronal deficits, and increased levels of amyloid‐ β (A β ) peptides. Cholinergic treatment could be the best suitable physiological therapy for AD . Calc...
Nikhil Tandon, Yashdeep Gupta, Deksha Kapoor, Josyula K. Lakshmi et al.
Importance: Women with recent gestational diabetes (GDM) have increased risk of developing type 2 diabetes. Objective: To investigate whether a resource-appropriate and context-appropriate lifestyle intervention could prevent glycemic deterioration among women with recent GDM in South Asia. Design, ...
Abdullah H Baqui, Dipak Kumar Mitra, Nazma Begum, Lisa Hurt et al.
OBJECTIVE: To estimate neonatal mortality, particularly within 24 hours of birth, in six low- and lower-middle-income countries. METHODS: We analysed epidemiological data on a total of 149 570 live births collected between 2007 and 2013 in six prospective randomized trials and a cohort study from pr...
Fahad Aftab, Imran Ahmed, Salahuddin Ahmed, Said M. Ali et al.
BACKGROUND: Maternal morbidity occurs several times more frequently than mortality, yet data on morbidity burden and its effect on maternal, foetal, and newborn outcomes are limited in low- and middle-income countries. We aimed to generate prospective, reliable population-based data on the burden of...
Rajiv Chowdhury, Dewan S Alam, Ismail Ibrahim Fakir, Sheikh Daud Adnan et al.
During recent decades, Bangladesh has experienced a rapid epidemiological transition from communicable to non-communicable diseases. Coronary heart disease (CHD), with myocardial infarction (MI) as its main manifestation, is a major cause of death in the country. However, there is limited reliable e...
The Antibiotics for Children With Diarrhea (ABCD) Study Group, Tahmeed Ahmed, Mohammod Jobayer Chisti, Muhammad Waliur Rahman et al.
Importance: World Health Organization (WHO) guidelines do not recommend routine antibiotic use for children with acute watery diarrhea. However, recent studies suggest that a significant proportion of such episodes have a bacterial cause and are associated with mortality and growth impairment, espec...
Jeffrey D. Wall, J. Fah Sathirapongsasuti, Ravi Gupta, Asif Rasheed et al.
The benefits of large-scale genetic studies for healthcare of the populations studied are well documented, but these genetic studies have traditionally ignored people from some parts of the world, such as South Asia. Here we describe whole genome sequence (WGS) data from 4806 individuals recruited f...
Kshitij Jagtap, R Naveen, Jessica Day, Parikshit Sen et al.
OBJECTIVE: Flares of autoimmune rheumatic diseases (AIRDs) following COVID-19 vaccination are a particular concern in vaccine-hesitant individuals. Therefore, we investigated the incidence, predictors and patterns of flares following vaccination in individuals living with AIRDs, using global COVID-1...
Vanita Noronha, Atul Budukh, Pankaj Chaturvedi, Anne Srikanth et al.
rearrangements are noted in 5-7%. Therapies are similar to global standards, although access to newer modalities and molecules is a challenge. Collaborative research, political will with various policy changes and patient advocacy are urgently needed.
Patricia B. Pavlinac, James A Platts-Mills, Jie Liu, Hannah E Atlas et al.
BACKGROUND: Bacterial pathogens cause substantial diarrhea morbidity and mortality among children living in endemic settings, yet antimicrobial treatment is only recommended for dysentery or suspected cholera. METHODS: AntiBiotics for Children with severe Diarrhea was a 7-country, placebo-controlled...
Fahad Aftab, Salahuddin Ahmed, Said M. Ali, Shaali Makame et al.
Cohort Profile: The Alliance for Maternal and Newborn Health Improvement (AMANHI) biobanking study Fahad Aftab, Salahuddin Ahmed, Said Mohammed Ali, Shaali Makame Ame, Rajiv Bahl,* Abdullah H Baqui , Nabidul Haque Chowdhury, Saikat Deb, Usha Dhingra, Arup Dutta, Tarik Hasan, Aneeta Hotwani, Muhammad...