Karen L. Kotloff, William C. Blackwelder, Dilruba Nasrin, James P. Nataro et al.
BACKGROUND: Diarrhea is a leading cause of illness and death among children aged <5 years in developing countries. This paper describes the clinical and epidemiological methods used to conduct the Global Enteric Multicenter Study (GEMS), a 3-year, prospective, age-stratified, case/control study to e...
Roger I. Glass, Stan Becker, M. I. Huq, Barbara J. Stoll et al.
Since 1963, the International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDR,B), formerly the Cholera Research Laboratory, has maintained a field station in Matlab to treat patients from a surveillance population of 240,000 who have cholera and other diarrheal diseases. Since 1966, the au...
Roger I. Glass, Jan Holmgren, Charles E. Haley, M. R. Khan et al.
At the Matlab Hospital of the International Centre for Diarrhoeal Disease Research, Bangladesh, the authors examined the blood groups of patients hospitalized between January and September 1979 for diarrheal disease due to a variety of bacterial and viral agents. A significant association was identi...
Leanne Unicomb, Goutam Podder, Jon R. Gentsch, Patricia Woods et al.
We characterized 1,534 rotavirus (RV) strains collected in Bangladesh from 1992 to 1997 to assess temporal changes in G type and to study the most common G and P types using reverse transcription-PCR, oligonucleotide probe hybridization, and monoclonal antibody-based enzyme immunoassay. Results from...
Barbara J. Stoll, Roger I. Glass, Mohammad Imdadul Huq, Muhammad Umer Khan et al.
In October 1979 a surveillance system was set up at the International Centre for Diarrhoeal Disease Research, Bangladesh, Hospital at Dacca to study a 4% systematic sample of the 100 000 patients with diarrhoea who come to the hospital for care each year. From December 1979 to November 1980 inclusiv...
Sandra Panchalingam, Martín Antonio, Anowar Hossain, Inácio Mandomando et al.
To understand the etiology of moderate-to-severe diarrhea among children in high mortality areas of sub-Saharan Africa and South Asia, we performed a comprehensive case/control study of children aged <5 years at 7 sites. Each site employed an identical case/control study design and each utilized a u...
Joseph Bresee, Zhao‐yin Fang, Bei Wang, E. Anthony S. Nelson et al.
Rotavirus remains the most common cause of severe, dehydrating diarrhea among children worldwide. Several rotavirus vaccines are under development. Decisions about new vaccine introduction will require reliable data on disease impact. The Asian Rotavirus Surveillance Network, begun in 2000 to facili...
Martin J. Blaser, Roger I. Glass, Mohsina Huq, Barbara J. Stoll et al.
To determine the prevalence of infection with Campylobacter fetus subsp. jejuni in Bangladesh, culture surveys were conducted among three populations. In Dacca, Campylobacter was isolated from 5.2% of 97 individuals with clinical dysentery and from 12.3% of 204 patients with only diarrhea. This diff...
Barbara J. Stoll, Roger I. Glass, M. I. Huq, Muhammad Umer Khan et al.
The epidemiologic and clinical characteristics of 412 patients infected with Shigella from a systematic sample of approximately 100,000 patients attending Dacca Hospital, International Centre for Diarrhoeal Disease Research, Bangladesh, between December 1, 1979, and November 30, 1980, were reviewed....
Roger I. Glass, I. Huq, A. R. M. A. Alim, Mohammad Yunus
In December 1979, a Vibrio cholerae O1 resistant to tetracycline, ampicillin, kanamycin, streptomycin, and trimethoprim-sulfamethoxazole was obtained from a patient with cholera at the Matlab Hospital, Bangladesh. All 256 isolates of V. cholerae O1 stocked in the previous six months were tested for ...
Mohanraj Ramachandran, Carl D. Kirkwood, Leanne Unicomb, Nigel A. Cunliffe et al.
Between 1992 and 1998, serotype G9 human rotavirus (RV) strains have been detected in 10 countries, including Thailand, India, Brazil, Bangladesh, Malawi, Italy, France, the United States, the United Kingdom, and Australia, suggesting the possible emergence of the fifth common serotype worldwide. Un...
Roger I. Glass, Barbara J. Stoll, Mohsina Huq, Marc Struelens et al.
Epidemiologic and clinical features of infection with Campylobacter jejuni in Bangladesh were examined in (1) diarrheal patients infected with C jejuni, (2) healthy control subjects, and (3) village children who were cultured monthly and at each diarrheal episode during a 10-month period. C jejuni w...
Mahmud Hossain, Roger I. Glass, M. R. Khan
Hossain M M (International Centre for Diarrhoeal Disease Research, GPO Box 128, Dacca-2, Bangladesh), Glass R I and Khan M R. Antibiotic use in a rural community in Bangladesh. International Journal of Epidemiology 1982, 11: 402–405. Antibiotic use by 175 000 people in the Matlab rural surveillance ...
Caryn Bern, Leanne Unicomb, Jon R. Gentsch, N Banul et al.
To improve the understanding of the relative importance of serotypes of rotavirus in dehydrating diarrhea, we examined the correlation of clinical characteristics and disease severity with serotype in 2,441 diarrheal episodes among children younger than 2 years of age in rural Bangladesh. Of 764 rot...
Leanne Unicomb, Paul E. Kilgore, Shah M. Faruque, Jena Hamadani et al.
OBJECTIVES: Rotavirus is the most common cause of severe diarrhea in children worldwide, and a vaccine may soon be licensed and available for use in immunization programs. To assess the need for a rotavirus vaccine in Bangladesh, we estimated the disease burden of rotavirus diarrhea from national vi...