Rosália Maria Tôrres de Lima, Antonielly Campinho dos Reis, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos et al.
Natural dietary agents have attracted considerable attention due to their role in promoting health and reducing the risk of diseases including cancer. Ginger, one of the most ancient known spices, contains bioactive compounds with several health benefits. [6]-Gingerol constitutes the most pharmacolo...
Marcus Vinícius Oliveira Barros de Alencar, Muhammad Torequl Islam, Ana Maria Oliveira Ferreira da Mata, Antonielly Campinho dos Reis et al.
Phytol (Pyt), a diterpenoid, possesses many important bioactivities. This study evaluates the anticancer effects of Pyt on sarcoma 180 (S-180) and human leukemia (HL-60) cell lines. For this purpose, cells were treated with Pyt (4.72, 7.08, or 14.16 μM) and a cell viability assay was performed. Addi...
Antônio Lima Braga, Ag‐Anne Pereira Melo de Menezes, José Victor de Oliveira Santos, Antonielly Campinho dos Reis et al.
Omeprazole (OME) is a proton pump inhibitor used for the treatment of various gastric and intestinal disease; however, studies on its effects on the genetic materials are still restricted. The present study aimed to evaluate possible toxicogenic effects of OME in Allium cepa meristems with the appli...
Ricardo Melo de Carvalho, Rai Pablo de Sousa Aguiar, Muhammad Torequl Islam, Marcus Vinícius Oliveira Barros de Alencar et al.
Cancer, the multifactorial pathology and to date is the most lethal causes of death in the world. Cyclophosphamide (CPA) and doxorubicin (DOX) are the individually or combindly used two anticancer drugs. The antineoplastic drugs-mediated genetic instability can be overcome by using antioxidants. The...
Erisson Cruz de Melo, Randyson da Silva Pinheiro, Bruno Sousa Costa, Rosália Maria Tôrres de Lima et al.
Toxicological studies are important to investigate the genotoxic effects of various substances. Allium cepa can be used as test model for this purpose. This review summarizes the scope and applications for this A. cepa test model. For this, an up-to-date (April 2023) literature search was made in th...