Soumen Chakraborty, Asish K. Mukhopadhyay, Rupak K. Bhadra, Amar N. Ghosh et al.
The virulence of a pathogen is dependent on a discrete set of genetic determinants and their well-regulated expression. The ctxAB and tcpA genes are known to play a cardinal role in maintaining virulence in Vibrio cholerae, and these genes are believed to be exclusively associated with clinical stra...
Tanuja Bhattacharya, Souvik Chatterjee, Diganta Maiti, Rupak K. Bhadra et al.
The ctxAB genes encoding cholera toxin, reside in the genome of a filamentous bacteriophage CTXphi. The presence of CTX prophage in non-epidemic environmental Vibrio cholerae strains is rare. The CTX prophage, the lysogenic form of CTXphi in V. cholerae, is comprised of the 'RS2' and the 'Core'. Ana...
Diganta Maiti, Bhabatosh Das, Arjun Saha, Ranjan K. Nandy et al.
The cholera toxin (CT) is a critical determinant of the virulence of epidemic Vibrio cholerae strains. The ctxAB operon encoding CT is part of the genome of a filamentous bacteriophage CTXPhi, which may integrate as a single copy or as multiple copies in the genome of V. cholerae. The CTXPhi genome ...
Shah M. Faruque, Manujendra N. Saha, Md Asadulghani, Prasanta K. Bag et al.
In order to assess the extent of genomic diversity among Vibrio cholerae O139 strains, restriction fragment length polymorphisms in two genetic loci, rrn and ctx, were studied. Analysis of 144 strains isolated from different regions of Bangladesh and India between 1992 and 1998 revealed the presence...
Abdul Abu Bakar, Elias Randjbaran, Данила Парыгин, R. Mohamad et al.