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Results for “"S. Thangapandiyan"”

3 results

Emerging promise of sulforaphane-mediated Nrf2 signaling cascade against neurological disorders

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Md. Sahab Uddin, Abdullah Al Mamun, Md. Jakaria, S. Thangapandiyan et al.

Journal: The Science of The Total EnvironmentYear: 2019Citations: 152

Neurological disorders represent a great challenge and are the leading cause of death and disability globally. Although numerous complicated mechanisms are involved in the progressions of chronic and acute neurodegenerative disorders, most of the diseases share mutual pathogenic features such as oxi...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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Cholinesterase Inhibitors for Alzheimer's Disease: Multitargeting Strategy Based on Anti-Alzheimer's Drugs Repositioning

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Md. Tanvir Kabir, Md. Sahab Uddin, Mst. Marium Begum, S. Thangapandiyan et al.

Journal: Current Pharmaceutical DesignYear: 2019Citations: 116

: In the brain, acetylcholine (ACh) is regarded as one of the major neurotransmitters. During the advancement of Alzheimer's disease (AD) cholinergic deficits occur and this can lead to extensive cognitive dysfunction and decline. Acetylcholinesterase (AChE) remains a highly feasible target for the ...

Health SciencesMedicinePharmacology
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Sulforaphane Potentially Ameliorates Arsenic Induced Hepatotoxicity in Albino Wistar Rats: Implication of PI3K/Akt/Nrf2 Signaling Pathway

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S. Thangapandiyan, Mathan Ramesh, Tamilselvan Hema, Selvaraj Miltonprabu et al.

Journal: Cellular Physiology and BiochemistryYear: 2019Citations: 49

BACKGROUND/AIMS: Agriculture and industrial expansion in recent years have resulted in the undue discharge of arsenic into the environment, building arsenic toxicity a major worldwide anxiety. Oxidative stress is considered as the most conspicuous effect of arsenic toxicity. The current study was de...

Physical SciencesEnvironmental ScienceEnvironmental ChemistryOpen Access
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