Zinia Haidar, Kaniz Fatema, Sabrina Samad Shoily, Abu Ashfaqur Sajib
Increased exposure to environmental heavy metals and metalloids and their associated toxicities has become a major threat to human health. Hence, the association of these metals and metalloids with chronic, age-related metabolic disorders has gained much interest. The underlying molecular mechanisms...
Sabrina Samad Shoily, Tamim Ahsan, Kaniz Fatema, Abu Ashfaqur Sajib
Diabetes mellitus is a complex and heterogeneous metabolic disorder which is often pre- or post-existent with complications such as cardiovascular disease, hypertension, inflammation, chronic kidney disease, diabetic retino- and nephropathies. However, the frequencies of these co-morbidities vary am...
Kaniz Fatema, Sabrina Samad Shoily, Tamim Ahsan, Zinia Haidar et al.
Various anthropogenic and natural events over the years have gradually increased human exposure to various heavy metals. Several of these heavy metals including cadmium, mercury, nickel, chromium, and the metalloid arsenic among others, have created major public health concerns for their high level ...
Tamim Ahsan, Sabrina Samad Shoily, Tasnim Ahmed, Abu Ashfaqur Sajib
Persistent cellular stress induced perpetuation and uncontrolled amplification of inflammatory response results in a shift from tissue repair toward collateral damage, significant alterations of tissue functions, and derangements of homeostasis which in turn can lead to a large number of acute and c...
Sabrina Samad Shoily, Kaniz Fatema, Rasheda Begum Dina, Anik Biswas et al.
BACKGROUND: Enzymatic catalysis in different industrial applications is often preferred over chemical methods due to various advantages, such as higher specificity, greater efficiency, and less environmental footprint. Pectinases are a group of enzymes that catalyze the degradation of pectic compoun...
Sabrina Samad Shoily, Tamim Ahsan, Kaniz Fatema, Abu Ashfaqur Sajib
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) mediated Coronavirus disease-19 (COVID-19) has affected millions of individuals around all corners of the globe. Symptoms and severities of infection with this highly contagious virus vary among individuals and there is disparity in the nu...
Sudipta Deb Nath, Sabrina Samad Shoily, Kaniz Fatema, Abira Khan et al.
Tamim Ahsan, Sabrina Samad Shoily, Kaniz Fatema, Abu Ashfaqur Sajib
Sulfotransferase 1A1 (SULT1A1), a major cytosolic sulfotransferase, can catalyze the sulfonation of both endogenous and exogenous compounds. It participates in the metabolism of several drugs and pro-carcinogens. Although certain variants of the SULT1A1 are known to alter responses to drugs and incr...
Tamim Ahsan, Kaniz Fatema, Sabrina Samad Shoily, Zinia Haidar et al.
The severity of the coronavirus disease 2019 (COVID-19) is linked to pro-inflammatory cytokine levels. There are still many unanswered questions regarding COVID-19 pathogenesis and prognosis. Significantly increased levels of pro-inflammatory cytokines characterize severe COVID-19 compared to those ...
Auroni Semonti Khan, Nahid Parvez, Tamim Ahsan, Sabrina Samad Shoily et al.
Background: Pirin, a member of the cupin superfamily, is an iron-binding non-heme protein. It acts as a coregulator of several transcription factors, especially the members of NFκB transcription factor family. Based on the redox state of its iron cofactor, it can assume two different conformations a...