David F. Choy, Kevin M. Hart, Lee A. Borthwick, Aarti Shikotra et al.
Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), endobronchial tissue gene expression analysis revealed three major patient clusters: TH2-high, TH17-high, and TH2/17...
Ali Raza, Sidra Charagh, Zainab Zahid, Muhammad Salman Mubarik et al.
Abiotic stresses are the primary sources of crop losses globally. The identification of key mechanisms deployed and established by plants in response to abiotic stresses is necessary for the maintenance of their growth and persistence. Recent discoveries have revealed that phytohormones or plant gro...
Shahida Anusha Siddiqui, Sayed Hashim Mahmood Salman, Ali Ali Redha, Oscar Zannou et al.
Sam Hodgson, Alice Williamson, Margherita Bigossi, Daniel Stow et al.
Abstract South Asians develop type 2 diabetes (T2D) early in life and often with normal body mass index (BMI). However, reasons for this are poorly understood because genetic research is largely focused on European ancestry groups. We used recently derived multi-ancestry partitioned polygenic scores...
Ferdaus Anam Jibon, Mahadi Hasan Miraz, Mayeen Uddin Khandaker, Mostafa Rashdan et al.
A clinical condition known as epilepsy occurs when the brain's regular electrical activity is disturbed, resulting in a rapid, aberrant, and excessive discharge of brain neurons. The electroencephalogram (EEG) signal is the measurement of electrical activity received from the nerve cells of the cere...
Adel Mansur, Sherif Gonem, Thomas Brown, Hassan Burhan et al.
BACKGROUND: several biological treatments have become available for management of severe asthma. There is a significant overlap in the indication of these treatments with lack of consensus on the first-line biologic choice and switching practice in event of treatment failure. AIMS: to evaluate outco...
Ferdaus Anam Jibon, Aditta Chowdhury, Mahadi Hasan Miraz, Hwang Ha Jin et al.
Automated epileptic seizure detection from ectroencephalogram (EEG) signals has attracted significant attention in the recent health informatics field. The serious brain condition known as epilepsy, which is characterized by recurrent seizures, is typically described as a sudden change in behavior c...
Muhammad Farooq, Adil Salman, Sohaib Ahmad Siddiqui, M. Ibrahim Khalil et al.
Developing countries like Pakistan, Bangladesh, and Nigeria etc. are facing severe energy and economic crises. The use and awareness of renewable energy system is strongly recommended for economic evolution of these countries. Moreover, they are also facing the problem of dreadful shortage of natura...
Aarti Shikotra, David F. Choy, Salman Siddiqui, Greer Arthur et al.
<b>Background:</b> Understanding the pathophysiology of severe asthma is essential for the development of novel therapies. Carcinoembryonic antigen cell adhesion molecule (CEACAM) family members are expressed in healthy lung tissue, and have properties that suggest they may play a role in asthma pat...
Timing Liu, Alagu Sankareswaran, Gordon Paterson, Shaheen Akhtar et al.
Correct classification of type 1 (T1D) and type 2 diabetes (T2D) is challenging due to overlapping clinical features and the increasingly early onset of T2D, particularly in South Asians. Polygenic risk scores (PRSs) for T1D and T2D have been shown to work relatively well in South Asians, despite be...
Arvind Keprate, Nikhil Bagalkot, M. Salman Siddiqui, Subhamoy Sen
Abu Z M Dayem Ullah, Ashitha Joby, Graeme J. Thorn, Lucas M. James et al.
South Asian populations remain underrepresented in cancer genomics, despite elevated risk for certain malignancies and distinct clinical profiles. This gap is especially pronounced for British Bangladeshi and Pakistani communities. We analyse data from 57,416 individuals of Bangladeshi and Pakistani...
Joseph E. Logan, Kirsty Wetherall, L.K. Gillespie, Alex McConnachie et al.
<h3>Introduction</h3> Remission is now an aspiration for asthma patients on biologics, although there is no agreed definition. Predicting the likelihood of remission at an early stage on treatment would improve precision therapy. <h3>Aims</h3> To identify the characteristics at 4 and 16 weeks on tre...
Salman Siddiqui, Rami J. Haddad
This paper explores a novel pedagogical approach incorporating Open Educational Resources (OER) and High Impact Practices (HIPs) for cultivating computational thinking in engineering education.It diverges from the conventional practice of introducing these concepts primarily through programming cour...
Mahesh K. Gathala, Thakur P. Tiwari, Saiful Islam, Md. Ashraf Ali et al.
Assistance received from DAE, BARI, and RADRS in Bangladesh; ICAR, BAU, UBKV, DoA-WB, Shakhi and JEEViKA in India, NARC and DoA in Nepal and community-based organizations (CBOs) in the region are thankfully acknowledged. The support received from CSIRO, Curtin University, University of Queensland, t...