Allan W. Taylor, Dianna M. Blau, Quique Bassat, Dickens Onyango et al.
BACKGROUND: Sub-Saharan Africa and south Asia contributed 81% of 5·9 million under-5 deaths and 77% of 2·6 million stillbirths worldwide in 2015. Vital registration and verbal autopsy data are mainstays for the estimation of leading causes of death, but both are non-specific and focus on a single un...
Syed Moshfiqur Rahman, Nabeel Ashraf Ali, Larissa Jennings, M. Habibur R. Seraji et al.
BACKGROUND: Well-trained and highly motivated community health workers (CHWs) are critical for delivery of many community-based newborn care interventions. High rates of CHW attrition undermine programme effectiveness and potential for implementation at scale. We investigated reasons for high rates ...
Gary L. Darmstadt, Yoonjoung Choi, Shams El Arifeen, Sanwarul Bari et al.
BACKGROUND: To evaluate a delivery strategy for newborn interventions in rural Bangladesh. METHODS: A cluster-randomized controlled trial was conducted in Mirzapur, Bangladesh. Twelve unions were randomized to intervention or comparison arm. All women of reproductive age were eligible to participate...
Navit T. Salzberg, Kasthuri Sivalogan, Quique Bassat, Allan W. Taylor et al.
Despite reductions over the past 2 decades, childhood mortality remains high in low- and middle-income countries in sub-Saharan Africa and South Asia. In these settings, children often die at home, without contact with the health system, and are neither accounted for, nor attributed with a cause of ...
Quique Bassat, Dianna M. Blau, Ikechukwu U. Ogbuanu, Solomon Samura et al.
Importance: The number of deaths of children younger than 5 years has been steadily decreasing worldwide, from more than 17 million annual deaths in the 1970s to an estimated 5.3 million in 2019 (with 2.8 million deaths occurring in those aged 1-59 months [53% of all deaths in children aged <5 years...
Gary L. Darmstadt, Samir K. Saha, Yoonjoung Choi, Shams El Arifeen et al.
BACKGROUND: To devise treatment strategies for neonatal infections, the population-level incidence and antibiotic susceptibility of pathogens must be defined. METHODS: Surveillance for suspected neonatal sepsis was conducted in Mirzapur, Bangladesh, from February 2004 through November 2006. Communit...
Solveig A. Cunningham, Nida Shaikh, Ariel Nhacolo, Pratima L. Raghunathan et al.
Health and demographic surveillance systems (HDSSs) provide a foundation for characterizing and defining priorities and strategies for improving population health. The Child Health and Mortality Prevention Surveillance (CHAMPS) project aims to inform policy to prevent child deaths through generating...
Shams El Arifeen, Samir K. Saha, Sayedur Rahman, Kazi Mizanur Rahman et al.
BACKGROUND: Streptococcus pneumoniae infection is recognized as a global priority public health problem, and conjugate vaccines have been shown to prevent vaccine-type invasive pneumococcal disease (IPD) in children. However, better estimates of the disease burden and reliable population-based data ...
Tabish Hazir, Khadija Begum, Shams El Arifeen, Amira M. Khan et al.
BACKGROUND: Antibiotic treatment for pneumonia as measured by Demographic and Health Surveys (DHS) and Multiple Indicator Cluster Surveys (MICS) is a key indicator for tracking progress in achieving Millennium Development Goal 4. Concerns about the validity of this indicator led us to perform an eva...
Zachary J. Madewell, Cynthia G. Whitney, Sithembiso Velaphi, Portia Mutevedzi et al.
Importance: Although child mortality trends have decreased worldwide, deaths among children younger than 5 years of age remain high and disproportionately circumscribed to sub-Saharan Africa and Southern Asia. Tailored and innovative approaches are needed to increase access, coverage, and quality of...
Dianna M. Blau, Vicky L. Baillie, Toyah Els, Sana Mahtab et al.
BACKGROUND: Lower respiratory tract infections are a leading cause of death in young children, but few studies have collected the specimens needed to define the role of specific causes. The Child Health and Mortality Prevention Surveillance (CHAMPS) platform aims to investigate causes of death in ch...
Sanwarul Bari, Ishtiaq Mannan, Mohammed Anisur Rahman, Gary L. Darmstadt et al.
The Projahnmo-II Project in Mirzapur upazila (sub-district), Tangail district, Bangladesh, is promoting care-seeking for sick newborns through health education of families, identification and referral of sick newborns in the community by community health workers (CHWs), and strengthening of neonatal...
Sana Mahtab, Dianna M. Blau, Zachary J. Madewell, Ikechukwu U. Ogbuanu et al.
BACKGROUND: The Child Health and Mortality Prevention Surveillance (CHAMPS) Network programme undertakes post-mortem minimally invasive tissue sampling (MITS), together with collection of ante-mortem clinical information, to investigate causes of childhood deaths across multiple countries. We aimed ...
Lola Madrid, Kartavya J. Vyas, Vijaya Kancherla, Haleluya Leulseged et al.
BACKGROUND: Neural tube defects are common birth defects resulting in severe morbidity and mortality; they can largely be prevented with periconceptional maternal intake of folic acid. Understanding the occurrence of neural tube defects and their contribution to mortality in settings where their bur...
Shema Mhajabin, Aniqa Tasnim Hossain, Nowrin Nusrat, Sabrina Jabeen et al.
OBJECTIVE: This paper presents the effect of the early phase of COVID-19 on the coverage of essential maternal and newborn health (MNH) services in a rural subdistrict of Bangladesh. DESIGN: Cross-sectional household survey with random sampling. SETTING: Baliakandi subdistrict, Rajbari district, Ban...