Yogesh Hooda, Mohammad Saiful Islam Sajib, Hafizur Rahman, Stephen P. Luby et al.
BACKGROUND: With the rise in fluoroquinolone-resistant Salmonella Typhi and the recent emergence of ceftriaxone resistance, azithromycin is one of the last oral drugs available against typhoid for which resistance is uncommon. Its increasing use, specifically in light of the ongoing outbreak of exte...
Denise O. Garrett, Ashley T Longley, Kristen Aiemjoy, Mohammad Tahir Yousafzai et al.
BACKGROUND: Precise enteric fever disease burden data are needed to inform prevention and control measures, including the use of newly available typhoid vaccines. We established the Surveillance for Enteric Fever in Asia Project (SEAP) to inform these strategies. METHODS: From September, 2016, to Se...
Megan E. Carey, Zoe A. Dyson, Danielle J. Ingle, Afreenish Amir et al.
Background: serovar Typhi (Typhi) genomic data to inform public health action. This analysis, which marks 22 years since the publication of the first Typhi genome, represents the largest Typhi genome sequence collection to date (n=13,000). Methods: This is a meta-analysis of global genotype and anti...
Senjuti Saha, Akshaya Ramesh, Katrina Kalantar, Roly Malaker et al.
Globally, there are an estimated 10.6 million cases of meningitis and 288,000 deaths every year, with the vast majority occurring in low- and middle-income countries. In addition, many survivors suffer from long-term neurological sequelae. Most laboratories assay only for common bacterial etiologies...
Senjuti Rahman, Mehedi Hasan, Ajay Krishno Sarkar
The brain is the human body's primary upper organ. Stroke is a medical disorder in which the blood arteries in the brain are ruptured, causing damage to the brain. When the supply of blood and other nutrients to the brain is interrupted, symptoms might develop. Stroke is considered as medical urgent...
Mohammad Saiful Islam Sajib, Arif Mohammad Tanmoy, Yogesh Hooda, Hafizur Rahman et al.
In the early 1900s, with mortality of ∼30%, typhoid and paratyphoid (caused by Salmonella Typhi and Paratyphi A) ravaged parts of the world; with improved water, sanitation, and hygiene in resource-rich countries and the advent of antimicrobials, mortality dwindled to <1%. Today, the burden rests...
Senjuti Kabir, S. M. Mazidur Rahman, Shakil Ahmed, Md Shamiul Islam et al.
BACKGROUND: The World Health Organization recommends the Xpert MTB/RIF Ultra assay for diagnosing pulmonary tuberculosis (PTB) in children. Though stool is a potential alternative to respiratory specimens among children, the diagnostic performance of Xpert Ultra on stool is unknown. Thus, we assesse...
Senjuti Rahman, Mehedi Hasan, Ajay Krishno Sarkar, Fayez Khan
Parkinson's disease (PD) is a chronic neurological condition that is growing in prevalence and manifests both motor and non-motor symptoms. Most PD patients have trouble speaking, writing, and walking during the early stages of the disease. Analysis of speech problems has been effective in identifyi...
Senjuti Saha, Arif Mohammad Tanmoy, Afroza Akter Tanni, Sharmistha Goswami et al.
### Summary box Bangladesh, a country of 166 million people, continues to be severely impacted by the COVID-19 pandemic. The first three cases of COVID-19 in Bangladesh were detected on 8 March 2020 among a group of travellers. Since then, the country has experienced two waves—in June 2020 and Apri...
Senjuti Saha, Arif Mohammad Tanmoy, Yogesh Hooda, Afroza Akter Tanni et al.
After several decades of debate, it is now widely acknowledged that apoptosis, also known as programmed cell death, is central to homoeostasis and normal development and physiology in all multicellular organisms, including humans. The dysregulation of apoptosis can lead to the destruction of normal ...
S. M. Mazidur Rahman, Umme Tasnim Maliha, Shahriar Ahmed, Senjuti Kabir et al.
BACKGROUND: The Xpert MTB/RIF (Xpert) assay technology allows rapid and sensitive diagnosis of pulmonary tuberculosis (PTB) from sputum specimens. However, diagnosis of PTB is difficult for patients who cannot produce sputum. The objective of this study was to investigate the use of Xpert assay for ...
Senjuti Saha, Roly Malaker, Mohammad Saiful Islam Sajib, Md Hasanuzzaman et al.
The complete genome sequence of a novel coronavirus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) isolate obtained from a nasopharyngeal swab from a patient with COVID-19 in Bangladesh is reported.
Sayera Banu, Farhana Haque, Shahriar Ahmed, Sonia Sultana et al.
BACKGROUND: In Bangladesh, about 80% of healthcare is provided by the private sector. Although free diagnosis and care is offered in the public sector, only half of the estimated number of people with tuberculosis are diagnosed, treated, and notified to the national program. Private sector engagemen...
Senjuti Saha, Maksuda Islam, Shampa Saha, Mohammad Jamal Uddin et al.
Background: Designing comprehensive surveillance to generate credible burden estimates of enteric fever in an endemic country can be challenging because care-seeking behavior is complex and surveillance in different healthcare facilities may lead to documentation of different epidemiological charact...
Abu S. M. S. B. Shahid, Tahmeed Ahmed, Senjuti Kabir, K. A. T. M. Ehsanul Huq et al.
Background. Exclusive breastfeeding is important for immunity and lack of breastfeeding during the neonatal age impedes that. Our aim was to assess the consequences of lack of breastfeeding on infants with diarrhea in the neonatal period. Methods. In this design, infants from DDSS (Diarrheal Disease...
Mahfuza Sahrin, Arfatur Rahman, Mohammad Khaja Mafij Uddin, Senjuti Kabir et al.
BACKGROUND: The Xpert® MTB/RIF assay detects Mycobacterium tuberculosis (MTB) and rifampicin (RIF) resistance. RIF-resistant (RIF-R) MTB cases detected using Xpert on sputum specimens at three private-sector TB screening centres in Dhaka, Bangladesh, were subjected to consecutive confirmatory Xpert ...
Shampa Saha, K M Ishtiaque Sayeed, Senjuti Saha, Md. Shafiqul Islam et al.
BACKGROUND: Enteric fever causes substantial morbidity and mortality in low- and middle-income countries. Here, we analyzed Surveillance for Enteric Fever in Asia Project (SEAP) data to estimate the burden of enteric fever hospitalization among children aged <15 years and identify risk factors for h...
Yogesh Hooda, Senjuti Saha, Mohammad S I Sajib, Hafizur Rahman et al.
With rising fluoroquinolone and ceftriaxone-resistant Salmonella Typhi, azithromycin, a macrolide, has become the last oral drug available against typhoid. Between 2009-2016, we isolated 1,082 Salmonella Typhi and Paratyphi A strains in Bangladesh, 13 (12 Typhi and 1 Paratyphi A) of which were azith...
Claudia Sala, Andrej Benjak, Delia Goletti, Sayera Banu et al.
The impact of tuberculosis and of anti-tuberculosis therapy on composition and modification of human lung microbiota has been the object of several investigations. However, no clear outcome has been presented so far and the relationship between M. tuberculosis pulmonary infection and the resident lu...
Md Hasanuzzaman, Senjuti Saha, Roly Malaker, Hafizur Rahman et al.
BACKGROUND: Sensitivity of culture for the detection of Streptococcus pneumoniae is limited by prior antibiotic exposure. Immunochromatographic test (ICT) is highly sensitive and specific for pneumococcal antigen detection in the cerebrospinal fluid (CSF) of meningitis cases. We determined the speci...