Marie Ng, Tom Fleming, Margaret S. Robinson, Blake Thomson et al.
Background In 2010, overweight and obesity were estimated to cause 3.4 million deaths, 3.9% of years of life lost, and 3.8% of DALYs globally. The rise in obesity has led to widespread calls for regular monitoring of changes in overweight and obesity prevalence in all populations. Comparative, up-to...
Theo Vos, Ryan M Barber, Brad Bell, Amelia Bertozzi-Villa et al.
Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities f...
John L. Wilkinson, Alistair B.A. Boxall, Dana W. Kolpin, Kmy Leung et al.
Environmental exposure to active pharmaceutical ingredients (APIs) can have negative effects on the health of ecosystems and humans. While numerous studies have monitored APIs in rivers, these employ different analytical methods, measure different APIs, and have ignored many of the countries of the ...
Lei Zhang, Xiao Qing Chen, Shuo Liu, Qian Zhang et al.
The recently proposed digital coding metasurfaces make it possible to control electromagnetic (EM) waves in real time, and allow the implementation of many different functionalities in a programmable way. However, current configurations are only space-encoded, and do not exploit the temporal dimensi...
Andrew Mente, Martin O’Donnell, Sumathy Rangarajan, Gilles R. Dagenais et al.
BACKGROUND Several studies reported a U-shaped association between urinary sodium excretion and cardiovascular disease events and mortality. Whether these associations vary between those individuals with and without hypertension is uncertain. We aimed to explore whether the association between sodiu...
Lei Liu, Taotao Li, Liang Ma, Weisheng Li et al.
Two-dimensional transition-metal dichalcogenides (TMDs) are of interest for beyond-silicon electronics 1,2 . It has been suggested that bilayer TMDs, which combine good electrostatic control, smaller bandgap and higher mobility than monolayers, could potentially provide improvements in the energy-de...
James A Platts-Mills, Jie Liu, Elizabeth T. Rogawski McQuade, Furqan Kabir et al.
BACKGROUND: Optimum management of childhood diarrhoea in low-resource settings has been hampered by insufficient data on aetiology, burden, and associated clinical characteristics. We used quantitative diagnostic methods to reassess and refine estimates of diarrhoea aetiology from the Etiology, Risk...
Elizabeth T. Rogawski McQuade, Jie Liu, James A Platts-Mills, Furqan Kabir et al.
BACKGROUND: Enteropathogen infections in early childhood not only cause diarrhoea but contribute to poor growth. We used molecular diagnostics to assess whether particular enteropathogens were associated with linear growth across seven low-resource settings. METHODS: We used quantitative PCR to dete...
Xiahai Zhuang, Lei Li, Christian Payer, Darko Štern et al.
Knowledge of whole heart anatomy is a prerequisite for many clinical applications. Whole heart segmentation (WHS), which delineates substructures of the heart, can be very valuable for modeling and analysis of the anatomy and functions of the heart. However, automating this segmentation can be chall...
Rongrong Huang, Lei He, Yanyan Xia, Hongpan Xu et al.
Abstract Emerging evidence indicates that exosomes derived from gastric cancer cells enhance tumor migration and invasion through the modulation of the tumor microenvironment. However, it remains a major problem to detect cancer‐specific exosomes due to technical and biological challenges. Most of t...
are the most fortunate generation that has ever lived. And are the most fortunate generation that ever will.--George MonbiotWhat George Monbiot means by this is that our civilization has leveraged the awesome power of fossil energy to create a world that only a short time ago would have been nearly ...
Margaret Kosek, Tahmeed Ahmed, Zulfiqar A Bhutta, Laura E. Caulfield et al.
BACKGROUND: Environmental enteropathy (EE), the adverse impact of frequent and numerous enteric infections on the gut resulting in a state of persistent immune activation and altered permeability, has been proposed as a key determinant of growth failure in children in low- and middle-income populati...
Jeffrey V. Lazarus, Diana Romero, Christopher J. Kopka, Salim S. Abdool Karim et al.
Abstract Despite notable scientific and medical advances, broader political, socioeconomic and behavioural factors continue to undercut the response to the COVID-19 pandemic 1,2 . Here we convened, as part of this Delphi study, a diverse, multidisciplinary panel of 386 academic, health, non-governme...
Daniel Balsalobre‐Lorente, Oana M. Driha, Nuno Carlos Leitão, Muntasir Murshed
Mitigation of carbon dioxide emissions has become an utmost important global agenda, keeping into consideration the associated environmental hardships. As a result, it is important to unearth the factors which can neutralize carbon emissions to transform the world economy into a low-carbon one. Agai...
Helen Harris–Fry, Kishwar Azad, Abdul Kuddus, Sanjit Kumer Shaha et al.
BACKGROUND: There has been limited decline in undernutrition rates in South Asia compared with the rest of Asia and one reason for this may be low levels of household food security. However, the evidence base on the determinants of household food security is limited. To develop policies intended to ...