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Results for “"Shailja Singhal"”

3 results

Emergence of SARS-CoV-2 Omicron (B.1.1.529) variant, salient features, high global health concerns and strategies to counter it amid ongoing COVID-19 pandemic

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Rekha Khandia, Shailja Singhal, Taha Alqahtani, Mohammad Amjad Kamal et al.

Journal: Environmental ResearchYear: 2022Citations: 320

Since the appearance in the late of December 2019, SARS-CoV-2 is rapidly evolving and mutating continuously, giving rise to various variants with variable degrees of infectivity and lethality. The virus that initially appeared in China later mutated several times, wreaking havoc and claiming many li...

Health SciencesMedicineInfectious DiseasesOpen Access
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Insight into Codon Utilization Pattern of Tumor Suppressor Gene EPB41L3 from Different Mammalian Species Indicates Dominant Role of Selection Force

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Utsang Kumar, Rekha Khandia, Shailja Singhal, Nidhi Puranik et al.

Journal: CancersYear: 2021Citations: 33

Uneven codon usage within genes as well as among genomes is a usual phenomenon across organisms. It plays a significant role in the translational efficiency and evolution of a particular gene. EPB41L3 is a tumor suppressor protein-coding gene, and in the present study, the pattern of codon usage was...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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An Insight into Codon Pattern Analysis of Autophagy Genes Associated with VirusInfection

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Shailja Singhal, Utsang Kumar, Taha Alqahtani, Igor Rzhepakovsky et al.

Journal: Current Pharmaceutical DesignYear: 2023Citations: 2

INTRODUCTION: Apoptosis and autophagy are the two fundamental processes involved in maintaining homeostasis, and a common stimulus may initiate the processes. Autophagy has been implicated in various diseases, including viral infections. Genetic manipulations leading to altered gene expression might...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular Biology
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