Shirajum Monira, Shota Nakamura, Kazuyoshi Gotoh, Kaori Izutsu et al.
Poor health and malnutrition in preschool children are longstanding problems in Bangladesh. Gut microbiota plays a tremendous role in nutrient absorption and determining the state of health. In this study, metagenomic tool was employed to assess the gut microbiota composition of healthy and malnouri...
Shirajum Monira, Shota Nakamura, Kazuyoshi Gotoh, Kaori Izutsu et al.
BACKGROUND: The diverse bacterial communities colonizing the gut (gastrointestinal tract) of infants as commensal flora, which play an important role in nutrient absorption and determining the state of health, are known to alter due to diarrhea. METHOD: Bacterial community dynamics in children suffe...
Christine Marie George, Shirajum Monira, David A. Sack, Mahamud‐ur Rashid et al.
The risk for cholera infection is >100 times higher for household contacts of cholera patients during the week after the index patient seeks hospital care than it is for the general population. To initiate a standard of care for this high-risk population, we developed Cholera-Hospital-Based-Interven...
Christine Marie George, Shwapon Biswas, Danielle Jung, Jamie Perin et al.
Inadequate hand hygiene is estimated to result in nearly 300,000 deaths annually, with the majority of deaths being among children younger than 5 years. In an effort to promote handwashing with soap and water treatment behaviors among highly susceptible household members of cholera patients, we rece...
Shirajum Monira, Syeda Antara Shabnam, Sk. Imran Ali, Abdus Sadique et al.
The gut of human harbors diverse commensal microbiota performing an array of beneficial role for the hosts. In the present study, the major commensal gut bacteria isolated by culturing methods from 15 children of moderate income families, aged between 10 and 24 months, were studied for their respons...
Nur Alam, Sufia Islam, Samima Sattar, Shirajum Monira et al.
OBJECTIVES: Assess the safety of rapid intravenous rehydration of severely malnourished children and compare the efficacy of 3 formulations of oral rehydration salts solutions. PATIENTS AND METHODS: A group of 175 severely malnourished children of either sex (weight/length <70% of National Center fo...
Khairun Nessa, Shama-A Waris, Zafar Sultan, Shirajum Monira et al.
The prevalence of sexually transmitted infections (STIs) and reproductive tract infections (RTIs) among hotel-based sex workers (HBSWs) in Dhaka, Bangladesh, was studied. A total of 400 HBSWs were enrolled in the study during April to July 2002. Endocervical swabs, high vaginal swabs, and blood samp...
Khairun Nessa, Shama A. Waris, Anadil Alam, M. I. Huq et al.
In Brief Objective and Goal: The goal of this study was to study the prevalence of sexually transmitted infections (STIs)/reproductive tract infections (RTIs) among brothel-based sex workers (SWs) in Bangladesh. Study: A cross-sectional study was conducted among SWs in 4 randomly selected brothels. ...
Fatema-Tuz Johura, Rozina Parveen, Atiqul Islam, Abdus Sadique et al.
Shiga-toxin producing Escherichia coli (STEC) and enterotoxigenic E. coli (ETEC) are important causes of diarrhea in humans and animals worldwide. Although ruminant animals are the main source of STEC, diarrhea due to this pathotype is very low in Bangladesh where ETEC remains the predominant group ...
Christine Marie George, Mahamud‐ur Rashid, David A. Sack, R. Bradley Sack et al.
BACKGROUND: To evaluate the specificity of the Crystal VC dipstick test for detecting cholera. METHODS: We compared direct testing using the Crystal VC dipstick test and testing after enrichment for 6 h in alkaline peptone water (APW) to bacterial culture as the gold standard. Samples positive by di...
Motiur Rahman, Md Ashraful Alam, K. Nessa, Shamsun Nahar et al.
Although ciprofloxacin is one of the recommended drugs of choice for the treatment of gonorrhea, in vitro resistance to this drug has been observed in surveillance studies and case reports from many parts of the world, including Bangladesh. However, to our knowledge, there have been no prospective s...
Raisa Rafique, Mahamud‐ur Rashid, Shirajum Monira, Zillur Rahman et al.
Recurrent cholera causes significant morbidity and mortality among the growing population of Dhaka, the capital city of Bangladesh. Previous studies have demonstrated that household contacts of cholera patients are at >100 times higher risk of cholera during the week after the presentation of the in...
Christine Marie George, Shirajum Monira, Fatema Zohura, Elizabeth Thomas et al.
BACKGROUND: The Cholera Hospital-Based Intervention for 7 Days (CHoBI7) mobile health (mHealth) program was a cluster-randomized controlled trial of diarrhea patient households conducted in Dhaka, Bangladesh. METHODS: Patients were block-randomized to 3 arms: standard message on oral rehydration sol...
Aminul Islam, Zillur Rahman, Shirajum Monira, Md. Anisur Rahman et al.
Of 48 bacteria belonging to the family Enterobacteriaceae tested from urban sludge samples, one Escherichia coli isolate was resistant to colistin and possessed the resistance marker gene mcr-1 found for the first time from Bangladesh. The colistin resistant E. coli was multidrug resistant showing r...
Christine Marie George, Danielle Jung, KM Saif‐Ur‐Rahman, Shirajum Monira et al.
Diarrhea is the second leading cause of death in children under 5 years of age globally. The time patients and caregivers spend at a health facility for severe diarrhea presents the opportunity to deliver water, sanitation, and hygiene (WASH) interventions. We recently developed Cholera-Hospital-Bas...