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Results for “"Shoumen Lasker"”

8 results

High-fat diet-induced metabolic syndrome and oxidative stress in obese rats are ameliorated by yogurt supplementation

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Shoumen Lasker, Md Mizanur Rahman, Faisal Parvez, Mushfera Zamila et al.

Journal: Scientific ReportsYear: 2019Citations: 246

The main objective of this experiment was to determine the effects of yogurt supplementation on fat deposition, oxidative stress, inflammation and fibrosis in the liver of rats with high-fat (HF) diet-induced obesity. Male Wistar rats were used in this study and were separated into the following fou...

Health SciencesMedicinePhysiologyOpen Access
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Canagliflozin attenuates isoprenaline-induced cardiac oxidative stress by stimulating multiple antioxidant and anti-inflammatory signaling pathways

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Raquibul Hasan, Shoumen Lasker, Ahasanul Hasan, Farzana Zerin et al.

Journal: Scientific ReportsYear: 2020Citations: 108

The antidiabetic drug canagliflozin is reported to possess several cardioprotective effects. However, no studies have investigated protective effects of canagliflozin in isoprenaline (ISO)-induced cardiac oxidative damage-a model mimicking sympathetic nervous system (SNS) overstimulation-evoked card...

Health SciencesMedicineCardiology and Cardiovascular MedicineOpen Access
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Canagliflozin ameliorates renal oxidative stress and inflammation by stimulating AMPK–Akt–eNOS pathway in the isoprenaline-induced oxidative stress model

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Raquibul Hasan, Shoumen Lasker, Ahasanul Hasan, Farzana Zerin et al.

Journal: Scientific ReportsYear: 2020Citations: 107

Diabetes is a leading cause of chronic kidney disease, and the high prevalence of sympathetic nervous system (SNS) hyperactivity in diabetic patients makes them further susceptible to SNS-mediated oxidative stress and accelerated kidney damage. Here, we investigated if canagliflozin can reverse isop...

Health SciencesMedicineEndocrinology, Diabetes and MetabolismOpen Access
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Metformin treatment reverses high fat diet- induced non-alcoholic fatty liver diseases and dyslipidemia by stimulating multiple antioxidant and anti-inflammatory pathways

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Tahmina Yasmin, Md Mizanur Rahman, Ferdous Khan, Fariha Kabir et al.

Journal: Biochemistry and Biophysics ReportsYear: 2021Citations: 40

PURPOSE: This current study investigated the effect of metformin treatment on hepatic oxidative stress and inflammation associated with nonalcoholic fatty liver disease (NADLD) in high fat diet (HFD) fed rats. METHOD: Wistar rats were fed with a HFD or laboratory chow diet for 8 weeks. Metformin was...

Health SciencesMedicineEpidemiologyOpen Access
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Trichosanthes dioica Roxb. prevents hepatic inflammation and fibrosis in CCl4-induced ovariectomized rats

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Salma Khan, Md Mizanur Rahman, Fariha Kabir, Kamrun Nahar et al.

Journal: Clinical Nutrition ExperimentalYear: 2020Citations: 19

Plant-derived natural products have shown beneficial effects in many diseases associated with liver. The present study aimed to appraise the effects of Trichosanthes dioica (TD) peel extract on oxidative stress, inflammation as well as fibrosis exhibited by the ovariectomized rats in which hepatic d...

Health SciencesMedicineEpidemiologyOpen Access
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Etoricoxib treatment prevented body weight gain and ameliorated oxidative stress in the liver of high-fat diet–fed rats

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Fariha Kabir, Kamrun Nahar, Md Mizanur Rahman, Fariha Mamun et al.

Journal: Naunyn-Schmiedeberg s Archives of PharmacologyYear: 2020Citations: 8

The main focus of this study was to determine the role of etoricoxib in counterbalancing the oxidative stress, metabolic disturbances, and inflammation in high-fat (HF) diet-induced obese rats. To conduct this study, 28 male Wistar rats (weighing 190-210 g) were distributed randomly into four groups...

Health SciencesMedicinePharmacology
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COMPARATIVE STUDIES ON ANTIOXIDANT AND THROMBOLYTIC ACTIVITIES OF METHANOL AND ETHYLACETATE EXTRACTS OF TREMA ORIENTALIS

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A. K. Azad, Shoumen Lasker, Irfan-Ur- Rahaman, Ohidul Islam et al.

Journal: International Journal of Innovations in Biological and Chemical SciencesYear: 2016Citations: 2

The present study was carried out to evaluate in-vitro antioxidant, and thrombolytic activity of MeOH and EtOAc extracts Trema orientalis flowers. Antioxidant activity of the extracts was tested by using DPPH (1, 1diphenyl-2-picrylhydrazyl) free radical scavenging assay method whereas the thrombolyt...

Health SciencesMedicineBiochemistryOpen Access
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Canagliflozin provides cardioprotection and renoprotection against isoprenaline‐induced oxidative stress by stimulating AMPK‐Akt‐eNOS‐NO signaling axis

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Raquibul Hasan, Shoumen Lasker, Ahasanul Hasan, Mushfera Zamila et al.

Journal: The FASEB JournalYear: 2020

The antidiabetic drug canagliflozin, a SGLT2 inhibitor, has been reported to possess protective effects against ischemia‐reperfusion and chemically‐induced cardiac and renal injuries. However, to our knowledge, no studies have investigated the protective effects of canagliflozin in isoprenaline (ISO...

Health SciencesMedicineSurgery
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