Taibur Rahman, Md. Ismail Hosen, Md. Monirul Islam, Hossain Uddin Shekhar
Redox degenerative reactions of the biological system inevitably produce reactive oxygen species (ROS) and their derivatives. Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species (ROS), such as hydrogen pe...
Sajib Chakraborty, Taibur Rahman
Cancer is clearly the most deadly disease in the developed world as one in three people develop cancer during their lifetime. The cure for cancer is like the Holy Grail since most of the existing treatments are not effective enough to provide full protection from this disease. In recent years the bu...
Q. Shazia, Zamani Mohammad, Taibur Rahman, Hossain Uddin Shekhar
Beta thalassemia major is an inherited disease resulting from reduction or total lack of beta globin chains. Patients with this disease need repeated blood transfusion for survival. This may cause oxidative stress and tissue injury due to iron overload, altered antioxidant enzymes, and other essenti...
Alison Kuchta, Taibur Rahman, Erica L. Sennott, Taufiqur Rahman Bhuyian et al.
Vibrio cholerae O1 is a noninvasive enteric pathogen and serves as a model for studies of mucosal immunity. Although symptomatic V. cholerae infection induces durable protection against subsequent disease, vaccination with oral killed whole-cell V. cholerae stimulates less long-lasting protection ag...
Alaullah Sheikh, Farhana Khanam, Md. Abu Sayeed, Taibur Rahman et al.
BACKGROUND: Salmonella enterica serotype Typhi is a human-restricted intracellular pathogen and the cause of typhoid fever. Cellular immune responses are required to control and clear Salmonella infection. Despite this, there are limited data on cellular immune responses in humans infected with wild...
Sajib Chakraborty, Taibur Rahman, Rajib Chakravorty
Human immunodeficiency virus (HIV) possesses a major threat to the human life largely due to the unavailability of an efficacious vaccine and poor access to the antiretroviral drugs against this deadly virus. High mutation rate in the viral genome underlying the antigenic variability of the viral pr...
M. Mesbah Uddin, Sharif Akteruzzaman, Taibur Rahman, Anamul Hasan et al.
Thalassemia and other structural haemoglobinopathies are the major erythrocyte formation disorder prevalent in certain parts of the world including Bangladesh. We investigated 600 cases of anaemic patients referred from various parts of the country for diagnosis and counselling during 3 months (Apri...
Lutfe Ara, Waseq Billah, Farzana Bashar, Sakib Mahmud et al.
INTRODUCTION: Biomedical waste management (BMWM) has attracted attention across the world as improper management can pose a serious threat for healthcare workers (HCWs), the general population and the environment. This study aimed to analyse the effectiveness of a multi-modal intervention (MMI) to u...
Md. Taibur Rahman, Izabela Swierzy, Bryan Downie, Gabriela Salinas et al.
Toxoplasma gondii is an obligatory intracellular parasite that causes persistent infections in birds and mammals including ~30% of the world’s human population. Differentiation from proliferative and metabolically active tachyzoites to largely dormant bradyzoites initiates the chronic phase of infec...
Taibur Rahman, Atiqur Rahman, Sajib Chakraborty
Toxoplasma gondii is an intracellular, zoonotic protozoan parasite that causes toxoplasmosis. It can potentially infect almost all mammalian and avian hosts including one-third of the human population world-wide. The major target group of the parasite includes immunocompromised patients (e.g. AIDS, ...
Sajib Chakraborty, Taibur Rahman, Rajib Chakravorty, Alison Kuchta et al.
Induction of HIV-1-specific cytotoxic T lymphocyte (CTL) responses largely depends upon the presentation of CTL epitopes to the CD8(+) T cells aided by a large number of different HLA class I alleles. Although several studies showed the clustering pattern of HIV-1 CTL epitopes, the underlying reason...
Hasib Uddin Ahmed, Anik Paul, Zimam Mahmud, Taibur Rahman et al.
Nurun Nahar Nila, Zimam Mahmud, Anik Paul, Taibur Rahman et al.
Background: The Alternative Lengthening of Telomeres (ALT) pathway represents a non-canonical mechanism of telomere maintenance that operates independently of the conventional telomerase activity. The three biologically significant proteins, designated as SMARCAL1 (SWI/SNF-related matrix-associated ...
Tamanna Ashraf, Pankaj Kumar Sarker, Md. Ismail Hosen, Atiqur Rahman et al.
Toxoplasma gondii is an intracellular protozoan parasite that causes toxoplasmosis in around one-third of the world population, particularly in pregnant women and immunocompromised individuals. Diabetes mellitus (DM) is one of the most severe global health challenges in the 21st century, and especia...
Bonoshree Sarkar, Afroza Sultana, Nabila Nawar Binti, Farhana Tasnim Chowdhury et al.
Antibiotic resistance poses a significant global health threat, necessitating a thorough understanding of its prevalence in various ecological contexts. Medicinal plants, renowned for their therapeutic properties, host endophytic bacteria that produce bioactive compounds. Understanding antibiotic re...