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Results for “"Talha Jawaid"”

9 results

<i>In vitro</i> antioxidant and anti-inflammatory activities of green cardamom essential oil and <i>in silico</i> molecular docking of its major bioactives

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Aftab Alam, Talha Jawaid, Pravej Alam

Journal: Journal of Taibah University for ScienceYear: 2021Citations: 59

Essential oil of Elettaria cardamomum (Green cardamom) is effective in the treatment of various disease conditions. Globally, Guatemala is the leading producer of green cardamom fruits. Green-cardamom fruits from Guatemala were purchased from a Saudi Arabian market. The Guatemala cardamom essential ...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmacologyOpen Access
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Nanomaterials: A Potential Hope for Life Sciences from Bench to Bedside

Verified

Mahesh Uttamrao Shinde, Mohsina Patwekar, Faheem Patwekar, Majed A. Bajaber et al.

Journal: Journal of NanomaterialsYear: 2022Citations: 40

In this review we hope to explain regarding nanoparticles (NPs), Nanoparticles are very small materials that range from 1 to 100 nm size. And the subclasses of nanoparticles are mentioned. Nanomaterials are formulated by nanoparticles. Research on nanomaterials is used to improve in material technol...

Physical SciencesMaterials ScienceMaterials ChemistryOpen Access
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A Potential Notion on Alzheimer’s Disease: Nanotechnology as an Alternative Solution

Verified

Sudhir Suryakant Pange, Mohsina Patwekar, Faheem Patwekar, Saad Alghamdi et al.

Journal: Journal of NanomaterialsYear: 2022Citations: 14

Alzheimer’s disease is an eventually destroying disease of the overaged people featured by the dynamic and gradual brain erosion because of construction of extracellular plaques in the hippocampus. It is an undertreated and underrecognized disease that is becoming a major public health concern. From...

Health SciencesMedicinePharmacologyOpen Access
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Investigating the effects of four medicinal plants against dengue virus through QSAR modeling and molecular dynamics studies

Verified

Faisal Alotaibi, Faris F. Aba Alkhayl, Ahmed I. Foudah, Mohammad Azhar Kamal et al.

Journal: Journal of Biomolecular Structure and DynamicsYear: 2024Citations: 1

= -34.1 kcal/mol). Overall, the purpose of this study was to identify phytochemicals that inhibit NS5 function, that could be further tested experimentally to treat dengue virus (DENV).

Physical SciencesComputer ScienceComputational Theory and Mathematics
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Predictive Bioactivity Modeling and Structural Binding Analysis for the Identification of Potential SMYD3 Modulators

Verified

Abdullah R. Alzahrani, Zia Ur Rehman, Talha Jawaid, Abida Khan

Journal: Research SquareYear: 2026

SMYD3 is a lysine methyltransferase involved in epigenetic regulation and oncogenic transcription, making it an attractive yet challenging therapeutic target. This study presents an integrated computational workflow combining machine learning based quantitative structure-activity relationship (QSAR)...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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Exploring Mitochondrial Dysfunction and Protective Therapeutic Approaches to Counteract Its Role in Alzheimer’s Disease Progression

Verified

Sanjana Gupta, P. Mohamed Nihal, Talha Jawaid, Astik Manju Ashesh et al.

Journal: Current NeuropharmacologyYear: 2026

Alzheimer's disease (AD) is the primary cause of dementia, characterized by a progres-sive decrease in mental abilities and the accumulation of amyloid-beta (Aβ) peptides in the brain. The combination of these peptides leads to the development of neuritic plaques and neurofibrillary tangles that dis...

Health SciencesMedicinePhysiology
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Antibody Therapies Targeting Amyloid-β and Tau in Alzheimer’s Disease with Insights on Mechanisms, Clinical Trials, and Challenges

Verified

Astik Manju Ashesh, Sanjana Gupta, Talha Jawaid, Pranay Wal et al.

Journal: Current Topics in Medicinal ChemistryYear: 2026

Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) deposits and neurofibrillary tangles containing phosphorylated tau protein. Around 57 million people worldwide were estimated by the World Health Organization to have dementia in 2021, with AD being the most prevalent type. The burden of AD...

Health SciencesMedicinePhysiology
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Exploring Alectinib and Irinotecan as potential human kallikrein-1 inhibitors: a drug repurposing approach for cancer and dermatological disorders

Verified

Talha Jawaid, Mehnaz Kamal, Lamya Ahmed Al‐Keridis, Mohd Adnan et al.

Journal: Molecular SimulationYear: 2025

Finding effective therapies against complex diseases such as cancer is challenging. The discovery of new applications for existing compounds through drug repurposing is a promising strategy. A family of serine proteases, kallikrein-related peptidases (KLKs), including kallikrein-1 (KLK1), has divers...

Health SciencesMedicineGenetics
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Zingiberaceae-derived phytomolecules inhibit Japanese encephalitis virus RNA dependent RNA polymerase: a molecular dynamics study

Verified

Aftab Alam, Asma Anjum, Ehssan Moglad, Talha Jawaid et al.

Journal: Journal of Biomolecular Structure and DynamicsYear: 2024

The Japanese encephalitis virus, (JEV), is a flavivirus mostly transmitted by Culex mosquitoes mostly present in Southeast Asia and the Western Pacific region. Ardeid-wading birds are the natural reservoir of JEV; nonetheless, pigs are frequently a key amplifying host during epidemics in human popul...

Health SciencesMedicinePublic Health, Environmental and Occupational Health
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