Firdausi Qadri, Marjahan Akhtar, Taufiqur Rahman Bhuiyan, Mohiul Islam Chowdhury et al.
BACKGROUND: Enterotoxigenic Escherichia coli causes diarrhoea, leading to substantial mortality and morbidity in children, but no specific vaccine exists. This trial tested an oral, inactivated, enterotoxigenic E coli vaccine (ETVAX), which has been previously shown to be safe and highly immuongenic...
Tasnuva Wahed, Sheikh Shah Tanvir Kaukab, Nirod Chandra Saha, Iqbal Ansary Khan et al.
BACKGROUND: In endemic countries such as Bangladesh, consequences of cholera place an enormous financial and social burden on patients and their families. Cholera vaccines not only provide health benefits to susceptible populations but also have effects on the earning capabilities and financial stab...
Marjahan Akhtar, Mohiul Islam Chowdhury, Taufiqur Rahman Bhuiyan, Joanna Kaim et al.
The safety and immunogenicity of the second generation oral enterotoxigenic Escherichia coli (ETEC) vaccine ETVAX, consisting of inactivated recombinant E. coli strains over-expressing the colonization factors (CFs) CFA/I, CS3, CS5 and CS6 and the heat labile toxoid LCTBA, were evaluated in Banglade...
Renate Richardus, Khorshed Alam, Kallyan Kundu, Johan Chandra Roy et al.
OBJECTIVE: To assess the effectiveness of single-dose rifampicin (SDR) after bacillus Calmette-Guérin (BCG) vaccination in preventing leprosy in contacts. METHODS: This was a single-centre, cluster-randomized controlled trial at a leprosy control programme in northwest Bangladesh. Participants were ...
Afroza Akter, Tasnuva Ahmed, Imam Tauheed, Marjahan Akhtar et al.
BACKGROUND: COVID-19 caused by SARS-CoV-2 ranges from asymptomatic to severe disease and can cause fatal and devastating outcome in many cases. In this study, we have compared the clinical, biochemical and immunological parameters across the different disease spectrum of COVID-19 in Bangladeshi pati...
Rashed Jalal, Zaheer Iqbal, Matieu Henry, Gianluca Franceschini et al.
In response to prevailing classification inconsistency between land cover maps, developed by different organizations in different times at different scales, an object-based National Land Representation System (NLRS) for Bangladesh has been developed. The process, which began in 2013 and was complete...
Md. Jasim Uddin, Tasnuva Wahed, Nirod Chandra Saha, Sheikh Shah Tanvir Kaukab et al.
The oral cholera vaccine (Shanchol), along with other interventions, is a potential new measure to prevent or control cholera. A mass cholera-vaccination programme was launched in urban Dhaka, Bangladesh, during February-April 2011 targeting about 173,041 people who are at high risk of cholera. This...
Marjahan Akhtar, Md. Rashedul Islam, Fatema Khaton, Umma Hany Soltana et al.
Background: Understanding the characteristics of the humoral immune responses following COVID-19 vaccinations is crucial for refining vaccination strategies and predicting immune responses to emerging SARS-CoV-2 variants. Methods: A longitudinal analysis of SARS-CoV-2 spike receptor binding domain (...
Saleha Tanjin, Farhana Islam, Md Zakir Sultan, Asma Rahman et al.
A simple, sensitive and precise reversed phase high performance liquid chromatographic (RP-HPLC) method has been developed for the estimation of naproxen in pharmaceutical dosage forms. The method was developed using the mobile phase comprising of dibasic sodium phosphate buffer (Na2HPO4) at pH 7.80...
Birkneh Tilahun Tadesse, Farhana Khanam, Faisal Ahmmed, Justin Im et al.
BACKGROUND: Typhoid fever contributes to approximately 135 000 deaths annually. Achievable improvements in household water, sanitation, and hygiene (WASH) combined with vaccination using typhoid conjugate vaccines (TCVs) may be an effective preventive strategy. However, little is known about how imp...
Md. Mehedi Hasan, Chowdhury Abdullah Al Asif, Alina Barua, Archis Banerjee et al.
OBJECTIVE: To examine the association between household access to water, sanitation and handwashing (WaSH) facilities and child undernutrition in Bangladesh. DESIGN, SETTING AND PARTICIPANTS: Cross-sectional study of children less than 5 years using data collected from the 2019 Multiple Indicator Cl...
Imam Tauheed, Tasnuva Ahmed, Afroza Akter, Md Golam Firoj et al.
Background Enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae O1 are most common bacterial causes of diarrheal diseases in Bangladesh. This analysis projected distribution of ETEC and V. cholerae O1 among diarrheal patients of icddr,b, Dhaka hospital in two diarrheal peaks of 2022. Methodol...
Tanzia Islam Tithi, Md. Rafat Tahsin, Juhaer Anjum, Tasnuva Sharmin Zaman et al.
INTRODUCTION: The liver, the most important metabolic organ of the body, performs a wide variety of vital functions. Hepatic cell injury occurs by the activation of reactive oxygen species (ROS) that are generated by carbon tetrachloride (CCl4), xenobiotics, and other toxic substances through cytoch...
Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Afroza Akter, Md Saruar Bhuiyan et al.
We have earlier reported that a single dose of oral cholera vaccine (OCV) is protective in adults and children ≥5 years of age and sustained for 2 years. We enrolled participants (n = 240) from this study, between March-September 2017, over 3 years after receiving a primary single dose. Immune respo...
Justin Im, Farhana Khanam, Faisal Ahmmed, Deok Ryun Kim et al.
Modest improvements in household water, sanitation, and hygiene (WASH) and typhoid vaccination can reduce typhoid risk in endemic settings. However, empiric evaluation of their combined impact is lacking. A total of 62,756 persons residing in 80 clusters in a Kolkata slum were allocated randomly 1:1...
Fergus Chadwick, Jessica Clark, Shayan Chowdhury, Tasnuva Chowdhury et al.
Diagnostics for COVID-19 detection are limited in many settings. Syndromic surveillance is often the only means to identify cases but lacks specificity. Rapid antigen testing is inexpensive and easy-to-deploy but can lack sensitivity. We examine how combining these approaches can improve surveillanc...
Farjana Chowdhury, Senjuti Pal, Tasnuva Sharmin, Ridwan Bin Rashid et al.
The methanol extracts of leaf of Artocarpus chaplasha Roxb. and Bougainvillea spectabillis Willd. as well as their petroleum ether, carbon tetrachloride, chloroform and aqueous soluble partitionates were subjected to screenings for antioxidant, cytotoxic, thrombolytic, membrane stabilizing and antim...
Sharmin Reza Chowdhury, Shahana Akter, Tasnuva Sharmin, Farhana Islam Tasdique Mohammad Quadery
The antimicrobial activity of five medicinal plants was evaluated by disc diffusion method. Among those, some fraction of plant extracts (400 I¼g /disc) exhibited potent antimicrobial activity against five gram positive and seven gram negative bacteria and three fungi. Among the test samples of O. m...
Fahmida Dilnaz, Farzina Zafar, Tanzina Afroze, Ummul Barakat Zakia et al.
Despite tremendous advances in medicine over the past few decades and significantly improved understanding of the symptomology and contributors to breast cancer (BC) incidence, BC rates continue to rise worldwide, with BC being a leading cause of cancer-related death among women. To reduce BC incide...
Zakaria Shams Siam, Rubyat Tasnuva Hasan, Moajjem Hossain Chowdhury, Md. Shaheenur Islam Sumon et al.
Brain magnetic resonance imaging (MRI) offers intricate soft tissue contrasts that are essential for diagnosing diseases and conducting neuroscience research. At 7 Tesla (7T) magnetic field intensity, MRI enables increased resolution, enhanced tissue contrast, and improved SNR, compared to MRI colle...