Monika Karmin, Lauri Saag, Mário Vicente, Melissa A. Wilson Sayres et al.
It is commonly thought that human genetic diversity in non-African populations was shaped primarily by an out-of-Africa dispersal 50-100 thousand yr ago (kya). Here, we present a study of 456 geographically diverse high-coverage Y chromosome sequences, including 299 newly reported samples. Applying ...
Luca Pagani, Daniel J. Lawson, Evelyn Jagoda, Alexander Mörseburg et al.
High-coverage whole-genome sequence studies have so far focused on a limited number of geographically restricted populations, or been targeted at specific diseases, such as cancer. Nevertheless, the availability of high-resolution genomic data has led to the development of new methodologies for infe...
Ivan Bautmans, Margareta Lambert, Tony Mets
BACKGROUND: The 6 minutes walk test (6MWT) is a useful assessment instrument for the exercise capacity of elderly persons. The impact of the health status on the 6MWT-distance in elderly, however, remains unclear, reducing its value in clinical settings. The objective of this study was to investigat...
Paul Farmer, Charles Patrick Almazor, Emily T. Bahnsen, Donna Barry et al.
Meeting Cholera's Challenge to Haiti and the World: A Joint Statement on Cholera Prevention and Care
Haoxue Han, Yong Zhang, Nan Wang, Majid Kabiri Samani et al.
The high thermal conductivity of graphene and few-layer graphene undergoes severe degradations through contact with the substrate. Here we show experimentally that the thermal management of a micro heater is substantially improved by introducing alternative heat-escaping channels into a graphene-bas...
Robert E. Black, Olivier Fontaine, Laura Lamberti, Maharaj Kishan Bhan et al.
BACKGROUND: Childhood diarrhea deaths have declined more than 80% from 1980 to 2015, in spite of an increase in the number of children in low- and middle-income countries (LMIC). Possible drivers of this remarkable accomplishment can guide the further reduction of the half million annual child death...
Ilaria Lampronti, Dino Martello, Nicoletta Bianchi, Monica Borgatti et al.
In the present paper we show that extracts from Aegle marmelos Correa are able to inhibit the in vitro proliferation of human tumor cell lines, including the leukemic K562, T-lymphoid Jurkat, B-lymphoid Raji, erythroleukemic HEL, melanoma Colo38, and breast cancer MCF7 and MDA-MB-231 cell lines. Mol...
Chandan Kumar, Mohammad U. H. Joardder, Troy Farrell, Graeme J. Millar et al.
Intermittent microwave convective drying (IMCD) is an advanced technology that improves both energy efficiency and food quality in drying. Modelling of IMCD is essential to understand the physics of this advanced drying process and to optimize the microwave power level and intermittency during dryin...
Charles Ameh, Robert S. Kerr, Barbara Madaj, Mselenge Mdegela et al.
BACKGROUND: Healthcare provider training in Emergency Obstetric and Newborn Care (EmOC&NC) is a component of 65% of intervention programs aimed at reducing maternal and newborn mortality and morbidity. It is important to evaluate the effectiveness of this. METHODS: We evaluated knowledge and skills ...
John Srivastava Lambert
Medicinal plants are viewed as a possible bridge between sustainable development, affordable health care, and conservation of vital biodiversity. This paper outlines the importance and usage of such plants in national health care and conservation activities in selected countries--China, Thailand, In...
Cai Li, Yong Zhang, Jianwen Li, Lesheng Kong et al.
BACKGROUND: Penguins are flightless aquatic birds widely distributed in the Southern Hemisphere. The distinctive morphological and physiological features of penguins allow them to live an aquatic life, and some of them have successfully adapted to the hostile environments in Antarctica. To study the...
Elisabetta Lambertini, Roberta Piva, Mahmud Tareq Hassan Khan, Ilaria Lampronti et al.
In this study we determined the activity of extracts from Bangladeshi medicinal plants (Emblica officinalis, Aegle marmelos, Vernonia anthelmintica, Oroxylum indicum, Argemone mexicana) on human breast tumor cell lines. Extracts from E. officinalis and O. indicum displayed anti-proliferative activit...
Kirkby D. Tickell, Rumana Sharmin, E Deichsel, Laura Lamberti et al.
BACKGROUND: Host vulnerabilities associated with acute malnutrition could facilitate the ability of specific enteric pathogens to cause diarrhoea and associated mortality. Using data from the Global Enteric Multicenter Study, we assessed whether acute malnutrition modifies the association between co...
Qin Qin Huang, Neneh Sallah, Diana Dunca, Bhavi Trivedi et al.
Individuals with South Asian ancestry have a higher risk of heart disease than other groups but have been largely excluded from genetic research. Using data from 22,000 British Pakistani and Bangladeshi individuals with linked electronic health records from the Genes & Health cohort, we conducted ge...
Abualgasim Elgaili Abdalla, Nzungize Lambert, Xiangke Duan, Jianping Xie
The interleukin-10 (IL-10) family of cytokines consists of six immune mediators, namely IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. IL-10, IL-22, IL-24 and IL-26 are critical for the regulation of host defense against Mycobacterium tuberculosis infections. Specifically, IL-10 and IL-26 can suppress...