Marie Ng, Tom Fleming, Margaret S. Robinson, Blake Thomson et al.
Background In 2010, overweight and obesity were estimated to cause 3.4 million deaths, 3.9% of years of life lost, and 3.8% of DALYs globally. The rise in obesity has led to widespread calls for regular monitoring of changes in overweight and obesity prevalence in all populations. Comparative, up-to...
Theo Vos, Ryan M Barber, Brad Bell, Amelia Bertozzi-Villa et al.
Background Up-to-date evidence about levels and trends in disease and injury incidence, prevalence, and years lived with disability (YLDs) is an essential input into global, regional, and national health policies. In the Global Burden of Disease Study 2013 (GBD 2013), we estimated these quantities f...
Giacomo Bellani, John G. Laffey, Tài Pham, Eddy Fan et al.
IMPORTANCE: Limited information exists about the epidemiology, recognition, management, and outcomes of patients with the acute respiratory distress syndrome (ARDS). OBJECTIVES: To evaluate intensive care unit (ICU) incidence and outcome of ARDS and to assess clinician recognition, ventilation manag...
Saifon Chawanpaiboon, Joshua P. Vogel, Ann‐Beth Moller, Pisake Lumbiganon et al.
BACKGROUND: Preterm birth is the leading cause of death in children younger than 5 years worldwide. Although preterm survival rates have increased in high-income countries, preterm newborns still die because of a lack of adequate newborn care in many low-income and middle-income countries. We estima...
Shiv Kumar Sarin, Manoj Kumar, George Lau, Zaigham Abbas et al.
Worldwide, some 240 million people have chronic hepatitis B virus (HBV), with the highest rates of infection in Africa and Asia. Our understanding of the natural history of HBV infection and the potential for therapy of the resultant disease is continuously improving. New data have become available ...
Salim Yusuf, Philip Joseph, Sumathy Rangarajan, Shofiqul Islam et al.
Background: Global estimates of the impact of common modifiable risk factors on cardiovascular disease (CVD) and mortality are largely based on data from separate studies, using different methodologies. The Prospective Urban Rural Epidemiology (PURE) study overcomes these limitations by using simila...
Xiaohu You, Cheng‐Xiang Wang, Jie Huang, Xiqi Gao et al.
Abstract The fifth generation (5G) wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized, such as mass connectivity, ultra-reliability, and guaranteed low latency. However, 5G will not meet all requirements of the future...
Michael S. Kramer, Ritsuko Kakuma
BACKGROUND: Although the health benefits of breastfeeding are widely acknowledged, opinions and recommendations are strongly divided on the optimal duration of exclusive breastfeeding. Since 2001, the World Health Organization has recommended exclusive breastfeeding for six months. Much of the recen...
Gary E. Raskob, Nick van Es, Peter Verhamme, Marc Carrier et al.
BACKGROUND: Low-molecular-weight heparin is the standard treatment for cancer-associated venous thromboembolism. The role of treatment with direct oral anticoagulant agents is unclear. METHODS: In this open-label, noninferiority trial, we randomly assigned patients with cancer who had acute symptoma...
Keyan Zhao, Chih‐Wei Tung, Georgia C. Eizenga, Mark H. Wright et al.
Asian rice, Oryza sativa is a cultivated, inbreeding species that feeds over half of the world's population. Understanding the genetic basis of diverse physiological, developmental, and morphological traits provides the basis for improving yield, quality and sustainability of rice. Here we show the ...
Igor Rudan
Childhood pneumonia is the leading single cause of mortality in children aged less than 5 years. The incidence in this age group is estimated to be 0.29 episodes per child-year in developing and 0.05 episodes per child-year in developed countries. This translates into about 156 million new episodes ...
Tanvir Mahtab Uddin, Arka Chakraborty, Ameer Khusro, BM Redwan Matin Zidan et al.
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-molecular-weight bioactive agents have also been used for a variety of other medicinal applications. In the battle against microbes, antibiotics have certainly been a blessing to human civilization by savin...
Lianlin Li, Tie Jun Cui, Wei Ji, Shuo Liu et al.
Metasurfaces have enabled a plethora of emerging functions within an ultrathin dimension, paving way towards flat and highly integrated photonic devices. Despite the rapid progress in this area, simultaneous realization of reconfigurability, high efficiency, and full control over the phase and ampli...
Cathryn M. Lewis, Douglas F. Levinson, Lesley H. Wise, Lynn E. DeLisi et al.
Schizophrenia is a common disorder with high heritability and a 10-fold increase in risk to siblings of probands. Replication has been inconsistent for reports of significant genetic linkage. To assess evidence for linkage across studies, rank-based genome scan meta-analysis (GSMA) was applied to da...
Mahshid Dehghan, Andrew Mente, Xiaohe Zhang, Sumathi Swaminathan et al.
Background The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. Methods The Prospective Ur...