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Results for “"Wim H. van Brakel"”

9 results

Steroid prophylaxis for prevention of nerve function impairment in leprosy: randomised placebo controlled trial (TRIPOD 1)

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W Cairns S Smith, Alison Anderson, Stephen G Withington, Wim H. van Brakel et al.

Journal: BMJYear: 2004Citations: 89

OBJECTIVE: To determine whether addition of low dose prednisolone to multidrug treatment can prevent reaction and nerve function impairment in leprosy. DESIGN: Multicentre, double blind, randomised, placebo controlled, parallel group trial. SETTING: Six centres in Bangladesh and Nepal. PARTICIPANTS:...

Health SciencesMedicineInfectious DiseasesOpen Access
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Treatment with corticosteroids of long-standing nerve function impairment in leprosy: a randomized controlled trial (TRIPOD 3)

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Jan Hendrik Richardus, Stephen G Withington, Alison Anderson, RICHARD P. CROFT et al.

Journal: Leprosy ReviewYear: 2003Citations: 54

Some leprosy patients with long-standing nerve function impairment (NFI) appear to have responded favourably to treatment with corticosteroids. This study investigated whether patients with untreated NFI between 6 and 24 months duration and who are given standard regimen corticosteroid therapy, will...

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The prognostic importance of detecting mild sensory impairment in leprosy: a randomized controlled trial (TRIPOD 2)

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Wim H. van Brakel, Alison Anderson, Stephen G Withington, RICHARD P. CROFT et al.

Journal: Leprosy ReviewYear: 2003Citations: 51

This study was designed to investigate whether leprosy patients diagnosed with mild sensory impairment have a better prognosis when treated with steroids than similarly impaired patients treated with placebo. A multi-centre, randomized, double-blind, placebo-controlled trial was conducted in Nepal a...

Health SciencesMedicineInfectious DiseasesOpen Access
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Adverse events of standardized regimens of corticosteroids for prophylaxis and treatment of nerve function impairment in leprosy: results from the ‘TRIPOD’ trials

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Jan Hendrik Richardus, Stephen G Withington, Alison Anderson, RICHARD P. CROFT et al.

Journal: Leprosy ReviewYear: 2003Citations: 37

Reactions in leprosy causing nerve function impairment (NFI) are increasingly treated with standardized regimens of corticosteroids, often under field conditions. Safety concerns led to an assessment of adverse events of corticosteroids, based on data of three trials studying prevention of NFI (the ...

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The PEP++ study protocol: a cluster-randomised controlled trial on the effectiveness of an enhanced regimen of post-exposure prophylaxis for close contacts of persons affected by leprosy to prevent disease transmission

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Duane C. Hinders, Anneke T. Taal, Suchitra Lisam, Aymée M. da Rocha et al.

Journal: BMC Infectious DiseasesYear: 2024Citations: 13

BACKGROUND: Leprosy is an infectious disease with a slow decline in global annual caseload in the past two decades. Active case finding and post-exposure prophylaxis (PEP) with a single dose of rifampicin (SDR) are recommended by the World Health Organization as measures for leprosy elimination. How...

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The PEP++ study protocol: a cluster-randomised controlled trial on the effectiveness of an enhanced regimen of post-exposure prophylaxis for close contacts of persons affected by leprosy to prevent disease transmission

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Duane C. Hinders, Anneke T. Taal, Suchitra Lisam, Aymée M. da Rocha et al.

Journal: Research SquareYear: 2024Citations: 1

Abstract Background Leprosy is an infectious disease with a slow decline in global annual caseload in the past two decades. Active case finding and post-exposure prophylaxis (PEP) with a single dose of rifampicin (SDR) are recommended by the World Health Organization as measures for leprosy eliminat...

Health SciencesMedicineInfectious DiseasesOpen Access
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Sexual Health of Women with Spinal Cord Injury in Bangladesh

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Noortje P M Lubbers, Reshma Parvin Nuri, Wim H. van Brakel, Huib Cornielje

Journal: Disability CBR & Inclusive DevelopmentYear: 2012Citations: 1

Disability, CBR and Inclusive Development aims to enhance knowledge in the field of disability and inclusive development, addressing the needs of practitioners, policy makers, DPOs and the scientific community.

Health SciencesMedicinePathology and Forensic MedicineOpen Access
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Gaps in leprosy knowledge and hidden stigma in northwest Bangladesh: A community-based mixed-method survey among patients, contacts, communities and health workers

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Abu Sufian Chowdhury, Abhijit Saha, Johan Chandra Roy, Tanjum Ara Haque et al.

Journal: medRxivYear: 2026

Abstract Leprosy control requires early diagnosis, effective treatment and reduced stigma, yet community knowledge, attitudes and practices (KAP) in endemic settings remain poorly described. We assessed baseline leprosy-related KAP among key stakeholder groups in northwest Bangladesh. A community-ba...

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ORIGINAL RESEARCH Sexual Health of Women with Spinal Cord Injury in Bangladesh

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Noortje P M Lubbers, Reshma Parvin Nuri, Wim H. van Brakel, Huib Cornielje

Year: 2012

Purpose: To identify factors influencing the sexual health of women with spinal cord injury (SCI) in Bangladesh. Methods: This study used both qualitative and quantitative methods. The quantitative part used a case-control design. Cases were women with SCI and controls were age-matched women without...

Health SciencesMedicinePathology and Forensic Medicine
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