Tianshu Liu, Yuxian Bai, Xiaoyan Lin, Wěi Li et al.
First-line chemotherapy for advanced/metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric/gastroesophageal junction cancer (GC/GEJC) has poor median overall survival (OS; <1 year). We report efficacy and safety results from Chinese patients in the phase III global CheckMate 64...
Xiaochun Wei, Yingying Zhang, Yanyan Zhao, Zhengqing Xie et al.
Plasmodiophora brassicae , an obligate biotrophic pathogen-causing clubroot disease, can seriously affect Brassica crops worldwide, especially Chinese cabbage. Understanding the transcriptome and metabolome profiling changes during the infection of P. brassicae will provide key insights in understan...
Xiaochun Gu, Zhong Zhao, Xueli Chen, Lifeng Zhang et al.
Microglia surveillance manifests itself as dynamic changes in cell morphology and functional remodeling. Whether and how microglia surveillance is coupled to brain state switches during natural sleep-wake cycles remains unclear. To address this question, we used miniature two-photon microscopy (mTPM...
Peng Zeng, Xinjian Ren, Linfeng Wei, Haifeng Zhao et al.
Abstract In photon‐conversion processes, rapid cooling of photo‐induced hot carriers is a dominant energy loss channel. We herein report a 3‐fold reduced hot carrier cooling rate in CsPbBr 3 nanocrystals capped with a cross‐linked polysiloxane shell in comparison to single alkyl‐chain oleylamine lig...
Wei Chen, Jiang You, Xiaochun Gu, Congwu Du et al.
Abstract Noninvasive microvascular imaging using optical coherence Doppler tomography (ODT) has shown great promise in brain studies; however, high-speed microcirculatory imaging in deep brain remains an open quest. A high-speed 1.3 μm swept-source ODT (SS-ODT) system is reported which was based on ...
Xiaochun Wei, Abdur Rahim, Yanyan Zhao, Shuangjuan Yang et al.
Chinese cabbage is one of the most important and widely consumed vegetables in China. The developmental transition from the vegetative to reproductive phase is a crucial process in the life cycle of flowering plants. In spring-sown Chinese cabbage, late bolting is desirable over early bolting. In th...
Xiaochun Wei, Chunyang Meng, Yuxiang Yuan, Ujjal Kumar Nath et al.
Phytoene synthase (PSY) is the first committed enzyme in carotenoid biosynthesis, which plays important role in ripen fruit colour. However, the roles of CaPSY genes are not explained detail in ripen pepper fruit colour. In this study, three CaPSY genes (CaPSY1, CaPSY2 and CaPSY3) were identified th...
Jinlong Suo, Yibo Gan, Yangli Xie, Shuqin Xu et al.
The skeleton is an important structural and metabolic organ in human body, while aging is the physiological basis for degenerative skeletal diseases. China has the largest aging population in the world and faces great challenges in preventing and managing diseases related to skeletal aging. To addre...
Xiaochun Wei, Yanyan Lv, Yanyan Zhao, Ujjal Kumar Nath et al.
Cytoplasmic male sterility (CMS) is maternally inherited trait, which hinders the ability to produce viable pollen in plants. It serves as a useful tool for hybrid seed production via exploiting heterosis in crops. The molecular mechanism of CMS and fertility restoration has been investigated in dif...
Xiaochun Wei, Jundang Li, Xiaowei Zhang, Yanyan Zhao et al.
Clubroot disease caused by Plasmodiophora brassicae is one of the major threats to Brassica crops. New clubroot resistant varieties of Chinese cabbage (B. rapa ssp. pekinensis) have been developed through breeding, but the underlying genetic mechanism of clubroot resistance is still unclear. In this...
Peng Zeng, Xinjian Ren, Linfeng Wei, Haifeng Zhao et al.
Abstract In photon‐conversion processes, rapid cooling of photo‐induced hot carriers is a dominant energy loss channel. We herein report a 3‐fold reduced hot carrier cooling rate in CsPbBr 3 nanocrystals capped with a cross‐linked polysiloxane shell in comparison to single alkyl‐chain oleylamine lig...
Jiaming Li, Mengmeng Jiang, Qiaoran Wang, Zikai Zheng et al.
The global surge in the population of people 60 years and older, including that in China, challenges healthcare systems with rising age-related diseases. To address this demographic change, the Aging Biomarker Consortium (ABC) has launched the X-Age Project to develop a comprehensive aging evaluatio...
T. Okamoto, Xiaochun Wei, Hasan Mehraj, Mohammad Rashed Hossain et al.
Lijiao Hu, Xiaowei Zhang, Yuxiang Yuan, Zhiyong Wang et al.
Ogura cytoplasmic male sterility (Ogura CMS), originally identified in wild radish (Raphanus sativus), has enabled complete pollen sterility in Brassica plants, but the underlying mechanism in Ogura CMS Chinese cabbage (Brassica rapa ssp. pekinensis) remains unclear. In this study cytological analys...
Xiaochun Wei, Shixiong Xiao, Yanyan Zhao, Luyue Zhang et al.
Clubroot disease poses a significant threat to Brassica crops, necessitating ongoing updates on resistance gene sources. In F 2 segregants of the clubroot-resistant inbred line BrT18-6-4-3 and susceptible DH line Y510, the genetic analysis identified a single dominant gene responsible for clubroot r...