Lijuan Li, Yongqiang Yu, Yanli Tang, Pengfei Lin et al.
Abstract This paper introduces the Flexible Global Ocean‐Atmosphere‐Land System Model: Grid‐Point Version 3 (FGOALS‐g3) and evaluates its basic performance based on some of its participation in the sixth phase of the Coupled Model Intercomparison Project (CMIP6) experiments. Our results show that ma...
Jie Xu, Yibing Yuan, Yunbi Xu, Gengyun Zhang et al.
BACKGROUND: Drought stress is one of the major limiting factors for maize production. With the availability of maize B73 reference genome and whole-genome resequencing of 15 maize inbreds, common variants (CV) and clustering analyses were applied to identify non-synonymous SNPs (nsSNPs) and correspo...
Yong Han, Yanli An, Gang Jia, Xihui Wang et al.
Hepatocellular carcinoma (HCC) is frequently metastatic once diagnosed and less likely to respond to curative surgery, emphasizing the need for the development of more sensitive and effective diagnostic and therapeutic strategies. Epithelial cell adhesion molecule (EpCAM) is deemed as the biomarker ...
Xin Hua, Qiuli Xu, Ranpu Wu, Wei Sun et al.
BACKGROUND: Understanding the mechanisms that mediate the interaction between tumor and immune cells may provide therapeutic benefit to patients with cancer. The N6-methyladenosine (m6A) demethylase, ALKBH5 (alkB homolog 5), is overexpressed in non-small cell lung cancer. However, its role in the tu...
Rui Yang, Qiusha Tang, Fengqin Miao, Yanli An et al.
PURPOSE: To explore the thermoresistance and expression of heat-shock protein 90 (HSP90) in magnetic hyperthermia-treated human liver cancer stem-like cells (LCSCs) and the effects of a heat-shock protein HSP90 inhibitor 17-allylamino-17-demethoxgeldanamycin (17-AAG) on hepatocellular carcinoma-burd...
Chao Tian Tang, Ee Cheong Chua, Qian Hui Chew, Yanling He et al.
INTRODUCTION: Patterns of clinical use of long-acting injectable (LAI) antipsychotic drugs in many countries, especially in Asia, for treatment of patients diagnosed with chronic psychotic disorders including schizophrenia are not well established. METHODS: Within an extensive research consortium, w...
Shuangshuang Shi, Bin Zhu, Guiqian Tang, Cao Liu et al.
Abstract Aerosol optical effects can trigger complex changes in solar shortwave radiation (SW) in the atmosphere, resulting in significant impacts on the photochemistry and vertical structure of ozone. This paper provides observational evidence of aerosol absorbing and scattering effects on modifyin...
Lijuan Li, Li Dong, Jinbo Xie, Yanli Tang et al.
Abstract The Grid‐point Atmospheric Model of the IAP LASG version 3 (GAMIL3) has been developed by upgrading the horizontal resolution, methods of parallel computation, boundary layer scheme, aerosol parameterization, convective parameterization, stratocumulus cloud fraction scheme, land component, ...
Mengying Bao, Fang Cao, Yunhua Chang, Yanlin Zhang et al.
Kangli Xue, Rui Yang, Yanli An, Yinan Ding et al.
Ferroptosis, a unique iron-dependent mode of cell death characterized by lipid peroxide accumulation, holds significant potential for the treatment of glioblastoma (GBM). However, the effectiveness of ferroptosis is hindered by the limited intracellular ferrous ions (Fe2+) and hydrogen peroxide (H2O...
Yinan Ding, Hui-yan Ding, Han Li, Rui Yang et al.
Currently, the treatment of triple-negative breast cancer (TNBC) is limited by the special pathological characteristics of this disease. In recent years, photodynamic therapy (PDT) has created new hope for the treatment of TNBC. Moreover, PDT can induce immunogenic cell death (ICD) and improve tumor...
Wen Li, Qinge Zhang, Yi‐lang Tang, Seon‐Cheol Park et al.
Aims Schizophrenia is a major mental disorder with a wide range of psychiatric symptoms. This study explored the structure of psychiatric symptoms of schizophrenia using network analysis in a large representative Asian sample based on a survey of clinical features and treatment used in schizophrenia...
Jun Li, Qi Han, Yanqing Huang, Yanhui Wei et al.
Acute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with high mortality and poor outcome, especially for elderly/un fi t (age ≥ 60 years or un fi t patients who are ineligible to receive intensive chemotherapy) with adverse genetic and molecular abnormalities in the newly diagnosed ...
Xiaosu Zhou, Jiaqi Chen, Yan‐Lai Tang, Haibo Sun et al.
ABSTRACT: Integration of torque teno mini virus (TTMV) generating the TTMV::RARA (retinoic acid receptor α) fusion represents a newly recognized subtype of acute promyelocytic leukemia (APL) that merits detailed investigation. We present, to our knowledge, the first comprehensive characterization of...
Yang Fang, Xueping Tian, Yanling Jin, Anping Du et al.
Terrestrialization is an important evolutionary process that plants experienced. However, little is known about how land plants acquired aquatic growth behaviors. Here, we integrate multiproxy evidence to elucidate the evolution of the aquatic plant duckweed. Three genera of duckweeds show chronolog...