Khorshed Alam, Arpita Mazumder, Suranjana Sikdar, Yiming Zhao et al.
Natural products derived from microorganisms serve as a vital resource of valuable pharmaceuticals and therapeutic agents. Streptomyces is the most ubiquitous bacterial genus in the environments with prolific capability to produce diverse and valuable natural products with significant biological act...
Yanyan Zhang, Zhelong Jiang, Jianying Huang, Linda Y. Lim et al.
The state-of-the-art development of fabrication strategies of multi-dimensional titanate and titania nanostructures is reviewed first. This is followed by an overview of their potential applications in environmental, energy, and biomedical sectors.
Qian Xu, Yanyan Shen, Haifeng Wang, Niping Zhang et al.
Response surface methodology (RSM) based on a central composite design (CCD) was applied to optimise the extraction conditions for flavonoids from fructus sophorae with advantages in terms of resisting flavonoids during the whole process and maximising of extraction yield. Three aglycon forms of the...
Xue Chen, Zengyu Zhang, Minghua Gu, Hong Li et al.
Selenium (Se) deficiency is a public health concern that is mainly caused by inadequate intake of Se from staple crops. The purpose of this study is to investigate the effects of inoculation with different arbuscular mycorrhizal fungus (AMF) strains, including Funneliformis mosseae (Fm) and Glomus v...
Carina Fischer, Takahiro Seki, Sharon Lim, Masaki Nakamura et al.
Understanding the molecular mechanisms regulating beige adipocyte formation may lead to the development of new therapies to combat obesity. Here, we report a miRNA-based autocrine regulatory pathway that controls differentiation of preadipocytes into beige adipocytes. We identify miR-327 as one of t...
Xiaoman Zheng, Zengyu Zhang, Jiancheng Chen, Huanting Liang et al.
Arsenic (As) contamination in vegetables is a severe threat to human health. However, the evaluation of As relative bioavailability (As-RBA) or bioaccessibility in vegetables is still unexplored. The study sought to evaluate the As-RBA in commonly consumed ten leaf vegetables collected from As-pollu...
Huazhang Wu, Ying Hu, Xiufang Liu, Wei Song et al.
Long noncoding RNA (lncRNA) has been implicated in cancer, but little is known about the role of lncRNAs as regulators of tumor metastasis. In the present study, we demonstrate that lncRNA TRERNA1 acts like an enhancer of SNAI1 to promote cell invasion and migration and to contribute to metastasis o...
Wei Song, Chuqian Zheng, Min Liu, Ying Xu et al.
Hepatocellular carcinoma (HCC) is among the most common malignancies and has an unfavorable prognosis. The hepatitis B virus-encoded X (HBx) protein is closely associated with hepatocarcinogenesis. Sorafenib is a unique targeted oral kinase inhibitor for advanced HCC. Long noncoding RNAs (lncRNAs) m...
Gaochuan Zhang, Bingxue Shang, Ping Yang, Zhifei Cao et al.
Induced pluripotent stem cells (iPSCs) have recently boomed enthusiasm in stem cell therapy, whereas high potential tumorigenesis of iPSCs has become the biggest obstacle for clinic application and the tumorigenic genes in iPSCs have not been well documented. In this investigation, using tools of bi...
Yan Qin, Caicheng Huang, Guirong Huang, Hong Li et al.
Deficiencies of selenium (Se), a necessary microelement for humans, can be remedied by appropriately supplying Se-enriched rice. However, overconsumption of Se-enriched rice poses a potential risk. To accurately assess Se human health risks associated with Se-enriched rice consumption, we developed ...
Xiaochun Wei, Yingying Zhang, Yanyan Zhao, Zhengqing Xie et al.
Plasmodiophora brassicae , an obligate biotrophic pathogen-causing clubroot disease, can seriously affect Brassica crops worldwide, especially Chinese cabbage. Understanding the transcriptome and metabolome profiling changes during the infection of P. brassicae will provide key insights in understan...
Fahui Jiang, Xinwei Xue, Liyan Zhang, Yanyan Zuo et al.
Md. Shahinoor Islam, Yanyan Zhang, Kerry N. McPhedran, Yang Liu et al.
Naphthenic acids (NAs) found in oil sands process-affected waters (OSPW) have known environmental toxicity and are resistant to conventional wastewater treatments. The granular activated carbon (GAC) biofilm treatment process has been shown to effectively treat OSPW NAs via combined adsorption/biode...
Yanyan Li, Yongxia Zhai, Wei Liu, Kaixiang Zhang et al.
BACKGROUND: Cancer cells always develop ways to resist and evade chemotherapy. To overcome this obstacle, herein, we introduce a programmatic release drug delivery system that imparts avoiding drug efflux and nuclear transport in synchrony via a simple nanostructured drug strategy. RESULTS: The prog...
Yili Zang, Min Wang, M. J. I. Shohag, Lingli Lu et al.
Cadmium (Cd) and arsenic (As) in co-contaminated soil can enter the human body harming health via the food chain, such as vegetables. Biochar derived from waste has been used to reduce heavy metal uptake by plant, but long-term effects of biochar under Cd and As co-contaminated soil needs to be inve...