Xiaohu You, Cheng‐Xiang Wang, Jie Huang, Xiqi Gao et al.
Abstract The fifth generation (5G) wireless communication networks are being deployed worldwide from 2020 and more capabilities are in the process of being standardized, such as mass connectivity, ultra-reliability, and guaranteed low latency. However, 5G will not meet all requirements of the future...
Norihiro Kato, CARDIo GRAMplusCD, LifeLines Cohort Study, Marie Loh et al.
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10−11 to 5.0 × 10−21). ...
Quan Zhang, Tao Jin, Jianguo Cai, Liang Xu et al.
Gait and waist motions always contain massive personnel information and it is feasible to extract these data via wearable electronics for identification and healthcare based on the Internet of Things (IoT). There also remains a demand to develop a cost-effective human-machine interface to enhance th...
Wei Zhao, Asif Rasheed, Emmi Tikkanen, Jung‐Jin Lee et al.
To evaluate the shared genetic etiology of type 2 diabetes (T2D) and coronary heart disease (CHD), we conducted a genome-wide, multi-ancestry study of genetic variation for both diseases in up to 265,678 subjects for T2D and 260,365 subjects for CHD. We identify 16 previously unreported loci for T2D...
Md. Abdul Mazid, Carl Ward, Zhiwei Luo, Chuanyu Liu et al.
After fertilization, the quiescent zygote experiences a burst of genome activation that initiates a short-lived totipotent state. Understanding the process of totipotency in human cells would have broad applications. However, in contrast to in mice 1,2 , demonstration of the time of zygotic genome a...
Yin Peng, Yidan Xu, Xiaojing Zhang, Shiqi Deng et al.
Abstract Background Circular RNA (circRNA), a subclass of non-coding RNA, plays a critical role in cancer tumorigenesis and metastasis. It has been suggested that circRNA acts as a microRNA sponge or a scaffold to interact with protein complexes; however, its full range of functions remains elusive....
Zhanglei Pan, Jian Zhou, Ziyuan Lin, Yingmu Wang et al.
High salinity and high organic concentration impose negative impacts on autotrophic nitrification, which hinders efficient nitrogen removal. To achieve efficient nitrogen removal, high saline wastewater nitrogen removal systems with different COD/TN ratios based on heterotrophic nitrification-aerobi...
Ying Cui, Yun Jiao, Hua‐Jun Chen, Jie Ding et al.
OBJECTIVES: Type 2 diabetes mellitus is associated with increased risk for dementia. Patients with impaired cognition often show default-mode network disruption. We aimed to investigate the integrity of a default-mode network in diabetic patients by using independent component analysis, and to explo...
Ming Li, Congjiao Sun, Naiyi Xu, Peipei Bian et al.
Abstract The gene numbers and evolutionary rates of birds were assumed to be much lower than those of mammals, which is in sharp contrast to the huge species number and morphological diversity of birds. It is, therefore, necessary to construct a complete avian genome and analyze its evolution. We co...
Christopher M. Booth, D. Robert Siemens, Gavin Li, Yingwei Peng et al.
BACKGROUND: Practice guidelines recommend neoadjuvant chemotherapy (NACT) for bladder cancer. However, the evidence in support of adjuvant chemotherapy (ACT) is less robust. Here we describe whether the evidence of efficacy for NACT/ACT was sufficient to change clinical practice and whether the effi...
Minsheng You, Fushi Ke, Shijun You, Zhangyan Wu et al.
The diamondback moth, Plutella xylostella is a cosmopolitan pest that has evolved resistance to all classes of insecticide, and costs the world economy an estimated US $4-5 billion annually. We analyse patterns of variation among 532 P. xylostella genomes, representing a worldwide sample of 114 popu...
Dong Liang, Pengju Zhao, Jingfang Si, Lingzhao Fang et al.
Visible pigmentation phenotypes can be used to explore the regulation of gene expression and the evolution of coat color patterns in animals. Here, we performed whole-genome and RNA sequencing and applied genome-wide association study, comparative population genomics and biological experiments to sh...
Russell A. Johnson, Taher Uddin, Amena Aktar, M. Mohasin et al.
Immunity against Vibrio cholerae O1 is serogroup specific, and serogrouping is defined by the O-specific polysaccharide (OSP) part of lipopolysaccharide (LPS). Despite this, human immune responses to V. cholerae OSP have not previously been characterized. We assessed immune responses against V. chol...
Tie Jun Cui, Shuang Zhang, Andrea Alù, Martin Wegener et al.
Artículo escrito por un elevado número de autores, solo se referencian el que aparece en primer lugar, el nombre del grupo de colaboración, si le hubiere, y los autores pertenecientes a la UAM
Shijie Wang, Xiong Guo, Hong Zuo, Yin Gang Zhang et al.
OBJECTIVE: Kashin-Beck disease (KBD) is a chronic, endemic osteochondropathy principally occurring in children. We investigated apoptotic chondrocyte death and the expression of Bcl-2, Bax, Fas, and inducible nitric oxide synthase (iNOS) in articular cartilage from patients with KBD in order to dete...