Wei Zheng, Dale McLerran, Betsy Rolland, Xianglan Zhang et al.
BACKGROUND: Most studies that have evaluated the association between the body-mass index (BMI) and the risks of death from any cause and from specific causes have been conducted in populations of European origin. METHODS: We performed pooled analyses to evaluate the association between BMI and the r...
Charge Diabetes Working Group, Dajiang J. Liu, VA Million Veteran Program, Gina M. Peloso et al.
We screened variants on an exome-focused genotyping array in >300,000 participants (replication in >280,000 participants) and identified 444 independent variants in 250 loci significantly associated with total cholesterol (TC), high-density-lipoprotein cholesterol (HDL-C), low-density-lipoprotein ch...
Chuanfang Zhang, Yonglu Ma, Xuetao Zhang, Sina Abdolhosseinzadeh et al.
A family of 2D transition metal carbides and nitrides known as MXenes has received increasing attention since the discovery of Ti 3 C 2 in 2011. To date, about 30 different MXenes with well‐defined structures and properties have been synthesized, and many more are theoretically predicted to exist. D...
You Li, Rachel M Reeves, Xin Wang, Quique Bassat et al.
BACKGROUND: Influenza virus, respiratory syncytial virus, parainfluenza virus, and metapneumovirus are the most common viruses associated with acute lower respiratory infections in young children (<5 years) and older people (≥65 years). A global report of the monthly activity of these viruses is nee...
Shengxiong Huang, Yongfeng Gao, Ji‐Kai Liu, Xiaoli Peng et al.
The WRKY transcription factors have been implicated in multiple biological processes in plants, especially in regulating defense against biotic and abiotic stresses. However, little information is available about the WRKYs in tomato (Solanum lycopersicum). The recent release of the whole-genome sequ...
Qing Li, Yong Ni, Liren Zhang, Runqiu Jiang et al.
N6-methyladenosine (m6A), and its reader protein YTHDF1, play a pivotal role in human tumorigenesis by affecting nearly every stage of RNA metabolism. Autophagy activation is one of the ways by which cancer cells survive hypoxia. However, the possible involvement of m6A modification of mRNA in hypox...
Norihiro Kato, CARDIo GRAMplusCD, LifeLines Cohort Study, Marie Loh et al.
We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10−11 to 5.0 × 10−21). ...
Andrew A. Meharg, Enzo Lombi, Paul N. Williams, Kirk G. Scheckel et al.
Synchrotron-based X-ray fluorescence (S-XRF) was utilized to locate arsenic (As) in polished (white) and unpolished (brown) rice grains from the United States, China, and Bangladesh. In white rice As was generally dispersed throughout the grain, the bulk of which constitutes the endosperm. In brown ...
Paolo Boffetta, Dale McLerran, Yu Chen, Manami Inoue et al.
BACKGROUND: The occurrence of diabetes has greatly increased in low- and middle-income countries, particularly in Asia, as has the prevalence of overweight and obesity; in European-derived populations, overweight and obesity are established causes of diabetes. The shape of the association of overwei...
M. Sarwar Jahan, Abrar Saeed, Zhibin He, Yonghao Ni
Lijuan Li, Yongqiang Yu, Yanli Tang, Pengfei Lin et al.
Abstract This paper introduces the Flexible Global Ocean‐Atmosphere‐Land System Model: Grid‐Point Version 3 (FGOALS‐g3) and evaluates its basic performance based on some of its participation in the sixth phase of the Coupled Model Intercomparison Project (CMIP6) experiments. Our results show that ma...
Cindy Q. Tang, Tetsuya Matsui, Haruka Ohashi, Yi-Fei Dong et al.
Today East Asia harbors many "relict" plant species whose ranges were much larger during the Paleogene-Neogene and earlier. The ecological and climatic conditions suitable for these relict species have not been identified. Here, we map the abundance and distribution patterns of relict species, showi...
Feng Bai, Ni Shu, Yonggui Yuan, Yongmei Shi et al.
Alzheimer's disease (AD) can be conceptualized as a disconnection syndrome. Both remitted geriatric depression (RGD) and amnestic mild cognitive impairment (aMCI) are associated with a high risk for developing AD. However, little is known about the similarities and differences in the topological pat...
Yu Chen, W. K. Copeland, Rajesh Vedanthan, Eric J. Grant et al.
OBJECTIVE: To evaluate the association between body mass index and mortality from overall cardiovascular disease and specific subtypes of cardiovascular disease in east and south Asians. DESIGN: Pooled analyses of 20 prospective cohorts in Asia, including data from 835,082 east Asians and 289,815 so...
Patrick Munk, Christian Brinch, Frederik Duus Møller, Thomas Nordahl Petersen et al.
Antimicrobial resistance (AMR) is a major threat to global health. Understanding the emergence, evolution, and transmission of individual antibiotic resistance genes (ARGs) is essential to develop sustainable strategies combatting this threat. Here, we use metagenomic sequencing to analyse ARGs in 7...