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Results for “"Yun Ai"”

16+ results

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)<sup>1</sup>

Verified

Daniel J. Klionsky, Amal Kamal Abdel‐Aziz, Sara Abdelfatah, Mahmoud Abdellatif et al.

Journal: AutophagyYear: 2021Citations: 2602

autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.

Health SciencesMedicineEpidemiologyOpen Access
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Estimated global mortality associated with the first 12 months of 2009 pandemic influenza A H1N1 virus circulation: a modelling study

Verified

Fatimah S. Dawood, A. Danielle Iuliano, Carrie Reed, Martin I. Meltzer et al.

Journal: The Lancet Infectious DiseasesYear: 2012Citations: 1370

Background 18,500 laboratory-confirmed deaths caused by the 2009 pandemic influenza A H1N1 were reported worldwide for the period April, 2009, to August, 2010. This number is likely to be only a fraction of the true number of the deaths associated with 2009 pandemic influenza A H1N1. We aimed to est...

Health SciencesMedicineEpidemiology
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Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation

Verified

Norihiro Kato, CARDIo GRAMplusCD, LifeLines Cohort Study, Marie Loh et al.

Journal: Nature GeneticsYear: 2015Citations: 375

We carried out a trans-ancestry genome-wide association and replication study of blood pressure phenotypes among up to 320,251 individuals of East Asian, European and South Asian ancestry. We find genetic variants at 12 new loci to be associated with blood pressure (P = 3.9 × 10−11 to 5.0 × 10−21). ...

Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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Potential of Plant Bioactive Compounds as SARS-CoV-2 Main Protease (Mpro) and Spike (S) Glycoprotein Inhibitors: A Molecular Docking Study

Verified

Trina Ekawati Tallei, Sefren Geiner Tumilaar, Nurdjannah Jane Niode, Fatimawali Fatimawali et al.

Journal: ScientificaYear: 2020Citations: 272

Since the outbreak of the COVID-19 (coronavirus disease 19) pandemic, researchers have been trying to investigate several active compounds found in plants that have the potential to inhibit the proliferation of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The present study aimed to ...

Physical SciencesComputer ScienceComputational Theory and MathematicsOpen Access
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Incarceration history and risk of HIV and hepatitis C virus acquisition among people who inject drugs: a systematic review and meta-analysis

Verified

Jack Stone, Hannah Fraser, Aaron G. Lim, Josephine G. Walker et al.

Journal: The Lancet Infectious DiseasesYear: 2018Citations: 226

BACKGROUND: People who inject drugs (PWID) experience a high prevalence of incarceration and might be at high risk of HIV and hepatitis C virus (HCV) infection during or after incarceration. We aimed to assess whether incarceration history elevates HIV or HCV acquisition risk among PWID. METHODS: st...

Health SciencesMedicineEpidemiologyOpen Access
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Pre-referral rectal artesunate to prevent death and disability in severe malaria: a placebo-controlled trial

Verified

MF Gomes, MA Faiz, John O. Gyapong, Marian Warsame et al.

Journal: The LancetYear: 2008Citations: 226

Background Most malaria deaths occur in rural areas. Rapid progression from illness to death can be interrupted by prompt, effective medication. Antimalarial treatment cannot rescue terminally ill patients but could be effective if given earlier. If patients who cannot be treated orally are several ...

Health SciencesMedicinePublic Health, Environmental and Occupational HealthOpen Access
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Zinc for severe pneumonia in very young children: double-blind placebo-controlled trial

Verified

W. Abdullah Brooks, Mohammad Yunus, Mathuram Santosham, MA Wahed et al.

Journal: The LancetYear: 2004Citations: 225

Background Pneumonia is a leading cause of morbidity and mortality in young children. Early reversal of severity signs--chest indrawing, hypoxia, and tachypnoea--improves outcome. We postulated that zinc, an acute phase reactant, would shorten duration of severe pneumonia and time in hospital. Metho...

Health SciencesNursingNutrition and Dietetics
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Meta-analysis and systematic review of laparoscopic versus open mesh repair for elective incisional hernia

Verified

Aiman Awaiz, Faiz Ur Rahman, M. Belal Hossain, Rossita Mohamad Yunus et al.

Journal: HerniaYear: 2015Citations: 198

Context The utility of laparoscopic repair in the treatment of incisional hernia repair is still contentious. Objectives The aim was to conduct a meta-analysis of RCTs investigating the surgical and postsurgical outcomes of elective incisional hernia by open versus laparoscopic method. Data sources ...

Health SciencesMedicineSurgery
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Harnessing Solar Power: A Review of Photovoltaic Innovations, Solar Thermal Systems, and the Dawn of Energy Storage Solutions

Verified

M.M. Hasan, Shakhawat Hossain, M. Mofijur, Zobaidul Kabir et al.

Journal: EnergiesYear: 2023Citations: 197

The goal of this review is to offer an all-encompassing evaluation of an integrated solar energy system within the framework of solar energy utilization. This holistic assessment encompasses photovoltaic technologies, solar thermal systems, and energy storage solutions, providing a comprehensive und...

Physical SciencesEnergyRenewable Energy, Sustainability and the EnvironmentOpen Access
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Present and Future of SLAM in Extreme Environments: The DARPA SubT Challenge

Verified

Kamak Ebadi, Lukas Bernreiter, Harel Biggie, Gavin Catt et al.

Journal: IEEE Transactions on RoboticsYear: 2023Citations: 176

This article surveys recent progress and discusses future opportunities for simultaneous localization and mapping (SLAM) in extreme underground environments. SLAM in subterranean environments, from tunnels, caves, and man-made underground structures on Earth, to lava tubes on Mars, is a key enabler ...

Physical SciencesEngineeringAerospace EngineeringOpen Access
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Fear of COVID‐19 Scale (FCV‐19S) across countries: Measurement invariance issues

Verified

Chung‐Ying Lin, Wen‐Li Hou, Mohammed A. Mamun, José Aparecido Da Silva et al.

Journal: Nursing OpenYear: 2021Citations: 164

AIM: The threats of novel coronavirus disease 2019 (COVID-19) have caused fears worldwide. The Fear of COVID-19 Scale (FCV-19S) was recently developed to assess the fear of COVID-19. Although many studies found that the FCV-19S is psychometrically sound, it is unclear whether the FCV-19S is invarian...

Social SciencesPsychologyClinical PsychologyOpen Access
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ROS-Drp1-mediated mitochondria fission contributes to hippocampal HT22 cell apoptosis induced by silver nanoparticles

Verified

Xiaoru Chang, Shuyan Niu, Mengting Shang, Jiangyan Li et al.

Journal: Redox BiologyYear: 2023Citations: 154

Silver nanoparticles (AgNPs) have widely used in industrial and medical applications for their excellent antibacterial activities. AgNPs can penetrate into the brain and cause neuronal death, but limited evidence focused on toxic effects and mechanic study in hippocampal neuron. This study aimed to ...

Life SciencesNeuroscienceDevelopmental NeuroscienceOpen Access
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Low birth weight is associated with altered immune function in rural Bangladeshi children: a birth cohort study

Verified

Rubhana Raqib, Dewan S Alam, Protim Sarker, Shaikh Meshbahuddin Ahmad et al.

Journal: American Journal of Clinical NutritionYear: 2007Citations: 148

Background Low birth weight is generally an outcome of a fetal insult or nutritional insufficiency. Recent studies have shown that such exposure early in life may have long-term implications for later immunocompetence and susceptibility to infectious diseases. Objective We aimed to investigate the e...

Health SciencesMedicinePediatrics, Perinatology and Child HealthOpen Access
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Corporate social responsibility, innovation capability and firm performance: evidence from SME

Verified

Dawit Teclemariam Bahta, Jiang Yun, Md. Rashidul Islam, Muhammad Ashfaq

Journal: Social Responsibility JournalYear: 2020Citations: 146

Purpose The purpose of this paper is to examine corporate social responsibility (CSR) and its effect on small and medium enterprises’ (SMEs) innovation capability and financial performance from the perspective of a developing country. It also aims to explore the role of innovation capability as a me...

Social SciencesBusiness, Management and AccountingStrategy and Management
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Angiotensin IV attenuates diabetic cardiomyopathy <i>via</i> suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis

Verified

Meng Zhang, Wenhai Sui, Yanqiu Xing, Jing Cheng et al.

Journal: TheranosticsYear: 2021Citations: 144

The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV (Ang IV), in this disease and its underlying mechanism are unclear. This study was aimed to clarify the effects of Ang IV and its do...

Health SciencesMedicineEpidemiologyOpen Access
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