Zepeng He, Zhicheng Le, Yi Shi, Lixin Liu et al.
The development of lipid nanoparticles (LNPs) has enabled a successful clinical application of mRNA vaccines. However, disclosure of design principles for the core component-ionizable lipids (ILs), improving the delivery efficacy and organ targeting of LNPs, remains a formidable challenge. Herein, w...
Sheng Qiu, Guiqiu Zhao, Jing Lin, Xue Wang et al.
AIM: To review published clinical studies examining the effect of natamycin in the treatment of fungal keratitis. METHODS: We selected the publications in CENTRAL, MEDLINE, EMBASE, CNKI, and CBM. This study systematically reviewed published randomized controlled trials (RCTs) that compared natamycin...
Xiaoting Sun, Wenhai Sui, Zepeng Mu, Sisi Xie et al.
Metabolic reprogramming in malignant cells is a hallmark of cancer that relies on augmented glycolytic metabolism to support their growth, invasion, and metastasis. However, the impact of global adipose metabolism on tumor growth and the drug development by targeting adipose metabolism remain largel...
Zexuan Du, Jinze Li, Danyang Liu, Haoyang Li et al.
Zhan Gao, Haihong Yang, Zepeng He, Yizi Zhou et al.
Ionizable lipids (ILs) are critical components in mRNA vaccines, which have been instrumental in the global response to SARS-CoV-2. However, current commercialized ILs in mRNA vaccines are typically synthesized through multiple-step organic reactions, complicating quality control and driving up prod...
Zewei Luo, Junhao Shen, Ran Xu, Zepeng Huang et al.
Abstract It is important to directly characterize the modulus of objects through wearable systems, which can further develop electronic skin and human‐computer interaction. In this work, a modulus sensing system based on a pressure sensor and vibration module is developed. This resistive pressure se...
Zepeng He, Zhicheng Le, Yi Shi, Lixin Liu et al.
Abstract The development of lipid nanoparticles (LNPs) has enabled a successful clinical application of mRNA vaccines. However, disclosure of design principles for the core component‐ionizable lipids (ILs), improving the delivery efficacy and organ targeting of LNPs, remains a formidable challenge. ...
Guozhen Chen, Shirui Sun, Yingcong Guo, Qi He et al.
The prevalence of chronic kidney disease (CKD) in Asia was determined by comparing differences in age, sex, area, and analytical methods. This meta-analysis comprised 42 studies with 2,271,169 participants from five databases that were searched until February 30, 2025. The total prevalence of CKD 1-...