Zhengyuan Cheng, Manoj Hang Limbu, Zhi Wang, Jing Liu et al.
Gelatinases are members of the matrix metalloproteinase (MMPs) family; they play an important role in the degradation of the extracellular matrix (ECM). This effect is also crucial in the development and progression of chronic kidney disease (CKD). Its expression, as well as its activity regulation ...
Yu Zhang, Chuanbing Shi, Yiqiong Yang, Xiuxiu Hu et al.
Renal interstitial fibrosis (RIF) is a key feature of progressive chronic kidney disease (CKD), characterized by tubular epithelial cell (TEC) hypoxia and peritubular capillary (PTC) rarefaction. However, the mechanisms underlying these processes remain poorly understood. To address this knowledge g...
Fangchao Li, Jie Yuan, Xiaolin Meng, Panos Psimoulis et al.
Chenchen Zhao, Zhengyuan Shi, Xiangyu Wen, Chengjie Liu et al.
The emergence of multimodal large language models (MLLMs) presents promising opportunities for automation and enhancement in Electronic Design Automation (EDA). However, comprehensively evaluating these models in circuit design remains challenging due to the narrow scope of existing benchmarks. To b...
Yu Zhang, Chuanbing Shi, Yiqiong Yang, Jing Huang et al.
Abstract Renal interstitial fibrosis (RIF) is the prominent pathological characteristics of deteriorative chronic kidney disease (CKD), leading to peritubular capillary (PTC) rarefaction accompanied by obvious hypoxia. However, the underlying mechanisms remain elusive. To deal with this, we construc...