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Results for “"Zhongjian Chen"”

3 results

Oral delivery of proteins and peptides: Challenges, status quo and future perspectives

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Quangang Zhu, Zhongjian Chen, Pijush Paul, Yi Lü et al.

Journal: Acta Pharmaceutica Sinica BYear: 2021Citations: 322

Proteins and peptides (PPs) have gradually become more attractive therapeutic molecules than small molecular drugs due to their high selectivity and efficacy, but fewer side effects. Owing to the poor stability and limited permeability through gastrointestinal (GI) tract and epithelia, the therapeut...

Life SciencesPharmacology, Toxicology and PharmaceuticsPharmaceutical ScienceOpen Access
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Neogambogic acid prevents silica-induced fibrosis via inhibition of high-mobility group box 1 and MCP-1-induced protein 1

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Wei Zhang, Mei Zhang, Zhongjiang Wang, Yusi Cheng et al.

Journal: Toxicology and Applied PharmacologyYear: 2016Citations: 16

Background Silicosis is a systemic disease caused by inhaling silicon dioxide (SiO2); early stages are characterized by alveolar inflammation, and later stages are characterized by progressive lung fibrosis. Mounting evidence indicates that high-mobility group box 1 (HMGB1) is involved in pulmonary ...

Life SciencesBiochemistry, Genetics and Molecular BiologyClinical Biochemistry
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Layered Temporal Spatial Graph Attention Reinforcement Learning for Multiplex Networked Industrial Chains Energy Management

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Yuanshuang Jiang, Kai Di, Xingyu Wu, Zhongjian Hu et al.

Journal: Tsinghua Science & TechnologyYear: 2024Citations: 6

Demand response has recently become an essential means for businesses to reduce production costs in industrial chains. Meanwhile, the current industrial chain structure has also become increasingly complex, forming new characteristics of multiplex networked industrial chains. Fluctuations in real-ti...

Physical SciencesEngineeringElectrical and Electronic EngineeringOpen Access
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