Journal ArticleOpen Access
Genetic effects of welding fumes on the progression of neurodegenerative diseases
Author Affiliations
Green University of Bangladesh, Varendra University, University of Technology Sydney, University of Cambridge, ...
Published InNeuroToxicology
Year2018
Citations45
Abstract
Background Welding exposes different types of fumes, gases and radiant energy that can be potentially dangerous for unsafe welder’s health. Welding fumes (WFs) are a significant problem among all those exposed. WFs are a complex mixture of metallic oxides, silicates and fluorides that may result in different health effects. If a welder inhales such fumes in large quantities over a long period of time, there is a risk of various neurodegenerative diseases (NDGDs) development. Methods We developed quantitative frameworks to identify the genetic relationship of WFs and NDGDs. We analyzed Gene Expression microarray data from WFs exposed tissues and NDGDs including Parkinson’s disease (PD), Alzheimer’s disease (AD), Lou Gehrig’s disease (LGD), Epilepsy disease (ED), Multiple Sclerosis disease (MSD) datasets. We…
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