Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma

// Irfan A. Asangani 1,2,* ,Paul W. Harms 1,2,3,* , Lois Dodson 1 , Mithil Pandhi 1 , Lakshmi P. Kunju 2 , Christopher A. Maher 1,2,4 , Douglas R. Fullen 2,3 , Timothy M. Johnson 3 , Thomas J. Giordano 2 , Nallasivam Palanisamy 1,2,5,8 , Arul M. Chinnaiyan 1,2,5,6,7,8 1 Michigan Center for Translational Pathology 2 Department of Pathology, University of Michigan 3 Department of Dermatology, University of Michigan 4 Center for Computational Medicine and Bioinformatics 5 Comprehensive Cancer Center, University of Michigan Medical School 6 Howard Hughes Medical Institute, University of Michigan Medical School 7 Department of Urology, University of Michigan 8 Shared senior authors * These authors contributed equally to this work Correspondence: Arul M. Chinnaiyan,…