Brine shrimp toxicity study of different Bangladeshi medicinal plants

Twenty three Bangladeshi medicinal plants used in traditional medicines were evaluated for brine shrimp lethality toxicity. Different solvent extracts of Abroma augusta, Acanthus ilicifolius, Alstonia scholaris, Calotropis procera, Catharanthus roseus, Citrus grandis, Coccinia grandis, Croton tiglium, Cuscuta reflexa, Excoecaria agallocha, Heritiera fomes, Ipomoea aquatica, Lagerstroemia speciosa, Madhuca indica, Musa sapientum, Nypa fruticans, Piper peepuloides, Premna esculenta, Saraca asoca, Sonneratia apetala, Stevia rebaudiana, Syzygium fruticosum, and Trichosanthes dioica were used in the study. Of the 23 plants tested, about 80% were toxic to brine shrimp (LC50 < 30 g/ml). Among the extracts screened, the methanolic extract of Croton tiglium had the highest toxicity to brine shrimp (LC50 = 0.0924 g/ml). The drug vincristine sulfate was considered as reference standard.