Sitesh Chandra Bachar, Kishor Mazumder, Ritesh Bachar, Asma Aktar et al.
Currently, viral infection is the most serious health issue which causing unexpected higher rate of death globally. Many viruses are not yet curable, such as corona virus-2 (SARS-CoV-2), human immunodeficiency virus (HIV), hepatitis virus, human papilloma virus and so others. Furthermore, the toxici...
Kishor Mazumder, Asma Aktar, Priyanka Roy, Biswajit Biswas et al.
Cancer is a disorder that rigorously affects the human population worldwide. There is a steady demand for new remedies to both treat and prevent this life-threatening sickness due to toxicities, drug resistance and therapeutic failures in current conventional therapies. Researchers around the world ...
Zobaer Al Mahmud, Sitesh Chandra Bachar, Choudhury Mahmood Hasan, Talha Bin Emran et al.
Oleanolic acid (NZ-15), 7 α, 28-olean diol (NZ-38) and Stigmasterol (NZ-14) were isolated from the ethanolic extracts of the roots of Leea macrophylla (Family: Leeaceae) by using chromatographic analysis. This is the first report of isolation of these compounds from this plant. Their structures were...
AK Azad Chowdhury, Tapash Roy, ABM Faroque, Sitesh Chandra Bachar et al.
BACKGROUND: Understanding injection practices is crucial for evidence-based development of intervention initiatives. This study explored the extent of injection use and injection safety practices in primary care hospitals in Bangladesh. METHODS: The study employed both quantitative and qualitative r...
Zobaer Al Mahmud, Talha Bin Emran, Nazmul Qais, Sitesh Chandra Bachar et al.
BACKGROUND: The objective of this study was to investigate the antinociceptive, anti-inflammatory, thrombolytic and hepatoprotective activities of root extracts of Premna esculenta (family: Verbenaceae). METHODS: The analgesic activity was evaluated using the acetic-acid-induced writhing test in mic...
Achinta Saha, Mohammad A. Masud, Sitesh Chandra Bachar, Joydeb Kumar Kundu et al.
The petroleum ether, ethyl acetate, and methanol extracts of Phyllanthus reticulatus. Poir. (Euphorbiaceae) were chosen for pharmacological screening. In the acetic acid-induced writhing test, the ethyl acetate extract in doses of 150 and 300 mg/kg showed 51.23 and 65.12% inhibition of writhing, res...
Mohammed Rahmatullah, Imrul Sadeak, Sitesh Chandra Bachar, Tozammal Hossain et al.
Twenty three Bangladeshi medicinal plants used in traditional medicines were evaluated for brine shrimp lethality toxicity. Different solvent extracts of Abroma augusta, Acanthus ilicifolius, Alstonia scholaris, Calotropis procera, Catharanthus roseus, Citrus grandis, Coccinia grandis, Croton tigliu...
Md Jahidul Hasan, Raihan Rabbani, Ahmad Mursel Anam, Shihan Mahmud Redwanul Huq et al.
Abstract Purpose Hyperinflammation in severe COVID-19 infection increases the risk of respiratory failure and one of the cogent reasons of mortality associated with COVID-19. Baricitinib, a janus kinases inhibitor, can potentially suppress inflammatory cascades in severe COVID-19 pneumonia. Methods ...
Sitesh Chandra Bachar, Zimam Mahmud, Nazmul Qais
Premna esculenta Roxb. (family Verbenaceae) is a shrub used by the ethnic people of Chittagong Hill Tracts of Bangladesh for the treatment of hepatocellular jaundice. The present study was done to evaluate the hepatoprotective and the in vivo antioxidant activity of ethanolic extracts of leaves of t...
Md. Amirul Islam, Firoj Ahmed, Asish Kumar Das, Sitesh Chandra Bachar
The methanolic extract of Leonurus sibiricus aerial parts injected intraperitoneally at dose of 250 and 500 mg/kg showed a significant analgesic effect in acetic acid-induced writhing in mice. Moreover, when given orally to rats at dose of 200 and 400 mg/kg, it showed a significant anti-inflammatory...
Nilanjan Ghosh, Rituparna Ghosh, Zulfiqar Ali Bhat, Vivekananda Mandal et al.
Ischemic brain injury is one of the leading causes of death worldwide and has attracted a lot of attention in the field of drug discovery. Cerebral ischemia is a complex pathological process involving a series of mechanisms, including generation of free radicals, oxidative stress, disruption of the ...
Ranajit Kumar Sutradhar, Anika Rahman, Mesbah U. Ahmad, Sitesh Chandra Bachar
Mohummad Aminur Rahman, Sitesh Chandra Bachar, Mohammed Rahmatullah
Previous phytochemical analysis of methanolic extract of Acalypha indica L. has indicated the presence of steroid, flavonoid and terpenoid types of compounds. Since these compounds are of pharmacological interest, coupled with the use of this plant in traditional medicine, prompted us to check A. in...
Marina Nazneen, M.A. Mazid, Joydev K. Kundu, Sitesh Chandra Bachar et al.
The petroleum ether, ethyl acetate and methanol extracts of the aerial parts of Flacourtia indica (Burm. f.) Merr., were evaluated for hepato-protective properties. In paracetamol-induced hepatic necrosis in rat models, all extracts were found to reduce serum glutamic oxaloacetic transaminase (SGOT)...
Banibrata Das, Juthika Kundu, Sitesh Chandra Bachar, Mohammad Aftab Uddin et al.
An alkaloid constituent 1-[5-(1,3-benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine, trivial name piperine was isolated from Ludwigia hyssopifolia Linn. (Family-Onagraceae). The ethylacetate extract of the plant and the isolated compound piperine were studied for antitumor and in vitro antibacteria...