OtherOpen Access
An open dataset of Plasmodium vivax genome variation in 1,895 worldwide samples
Authors
Author Affiliations
University of Khartoum, International Centre for Diarrhoeal Disease Research, Mahidol University, BioReliance (United States), ...
Published InWellcome Open Research
Year2022
Citations52
Abstract
<ns3:p> This report describes the MalariaGEN Pv4 dataset, a new release of curated genome variation data on 1,895 samples of <ns3:italic>Plasmodium vivax</ns3:italic> collected at 88 worldwide locations between 2001 and 2017. It includes 1,370 new samples contributed by MalariaGEN and VivaxGEN partner studies in addition to previously published samples from these and other sources. We provide genotype calls at over 4.5 million variable positions including over 3 million single nucleotide polymorphisms (SNPs), as well as short indels and tandem duplications. This enlarged dataset highlights major compartments of parasite population structure, with clear differentiation between Africa, Latin America, Oceania, Western Asia and different parts of Southeast Asia. Each sample has been classified for drug resistance to sulfadoxine, pyrimethamine and mefloquine based…
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