Journal ArticleUnknown
Effect of peroxiredoxin II on the quality and mitochondrial activity of pre-implantation bovine embryos
Authors
Author Affiliations
Gyeongsang National University, Patuakhali Science and Technology University, Cairo University, Gyeongnam National University of Science and Technology, ...
Published InAnimal Reproduction Science
Year2015
Citations19
Abstract
Endogenous peroxiredoxin II (PRDX II) protein plays a vital role in early embryonic development. This study assessed the beneficial effects of exogenous PRDX II on bovine embryo development at the cellular and molecular levels. To this end, in vitro maturation (IVM) medium was supplemented with various concentrations of PRDX II (0, 6.25, 12.5, 25, 50, and 100μg/mL). Of these, 12.5μg/mL PRDX II was the most effective and significantly promoted embryonic development. Therefore, this concentration of PRDX II was used in subsequent experiments. The percentage of embryos that developed into Day 8 blastocysts and the total number of cells per blastocyst (38.2% and 150.6±5.1) was higher in the PRDX II-treated group than in the control (26.4% and 128.9±3.9, respectively). Moreover, the…
View at Publisher
BORR does not host full-text PDFs. The button above takes you to the original publisher.