Taibur Rahman, Md. Ismail Hosen, Md. Monirul Islam, Hossain Uddin Shekhar
Redox degenerative reactions of the biological system inevitably produce reactive oxygen species (ROS) and their derivatives. Oxidative stress is the result of an imbalance in pro-oxidant/antioxidant homeostasis that leads to the generation of toxic reactive oxygen species (ROS), such as hydrogen pe...
Cezary Waszczak, Salma Akter, Silke Jacques, Jingjing Huang et al.
In plants, fluctuation of the redox balance by altered levels of reactive oxygen species (ROS) can affect many aspects of cellular physiology. ROS homeostasis is governed by a diversified set of antioxidant systems. Perturbation of this homeostasis leads to transient or permanent changes in the redo...
Marcella Canton, Irina Neverova, Roberta Menabò, Jennifer E. Van Eyk et al.
Although the contribution of reactive oxygen species to myocardial ischemia is well recognized, the possible intracellular targets, especially at the level of myofibrillar proteins (MP), are not yet fully characterized. To assess the maximal extent of oxidative degradation of proteins, isolated rat ...
Salma Akter, Jingjing Huang, Cezary Waszczak, Silke Jacques et al.
Plants generate reactive oxygen species (ROS) as part of their metabolism and in response to various external stress factors, potentially causing significant damage to biomolecules and cell structures. During the course of evolution, plants have adapted to ROS toxicity, and use ROS as signalling mes...
Jun’ichi Mano, Md. Sanaullah Biswas, Koichi Sugimoto
As reactive oxygen species (ROS) play critical roles in plants to determine cell fate in various physiological situations, there is keen interest in the biochemical processes of ROS signal transmission. Reactive carbonyl species (RCS), the ,-unsaturated aldehydes and ketones produced from lipid pero...
Tahmina Islam, Mrinalini Manna, Malireddy K. Reddy
Reactive oxygen species (ROS) arise in the plant system due to inevitable influence of various environmental stimuli. Glutathione peroxidases are one of the important ROS scavengers inside the cell. A glutathione peroxidase (PgGPx) gene was previously found from Pennisetum glauccum abiotic stressed ...
Md. Morshedul Alam, Akihiro Kishino, Eunkyu Sung, Hiroki Sekine et al.
NF-E2-related factor 2 (NRF2) plays a crucial role in the maintenance of cellular homeostasis by regulating various enzymes and proteins that are involved in the redox reactions utilizing sulfur. While substantial impacts of NRF2 on mitochondrial activity have been described, the precise mechanism b...
Ye Sun, Tianyu Li, Hua Chen, Kun Zhang et al.
Glutathione peroxidase (GPX) is one of the most crucial antioxidant enzymes in a variety of organisms. Here we described a new strategy for generating a novel GPX mimic by combination of a phage-displayed random 15-mer peptide library followed by computer-aided rational design and chemical mutation....
Xiaoxuan Zhai, Shengchuan Cao, Jiali Wang, Bao Qiao et al.
BACKGROUND: Vascular calcification, which is characterized by calcium deposition in arterial walls and the osteochondrogenic differentiation of vascular smooth muscle cells, is an actively regulated process that involves complex mechanisms. Vascular calcification is associated with increased cardiov...
Shingo Kasamatsu, Akira Nishimura, Md. Morshedul Alam, Masanobu Morita et al.
Abundant formation of endogenous supersulfides, which include reactive persulfide species and sulfur catenated residues in thiols and proteins (supersulfidation), has been observed. We found here that supersulfides catalyze S -nitrosoglutathione (GSNO) metabolism via glutathione-dependent electron t...
Shi‐Yong Zhu, Lili Liu, Yue-Qiang Huang, Xiaowei Li et al.
Selenoprotein N (SEPN1) is critical to the normal muscular physiology. Mutation of SEPN1 can raise congenital muscular disorder in human. It is also central to maturation and structure of skeletal muscle in chicken. However, human SEPN1 contained an EF-hand motif, which was not found in chicken. And...
Md. Rashedunnabi Akanda, Myungjin Kim, In‐Shik Kim, Dongchoon Ahn et al.
Sigesbeckia pubescens (SP) is a traditional Chinese medicine, possessing antioxidant and anti-inflammatory activities. In this study, we evaluate the neuroprotective activities of SP extract on glutamate-induced oxidative stress in HT22 cells and the molecular mechanism underlying neuroprotection. W...
Salma Akter, Sébastien Carpentier, Frank Van Breusegem, Joris Messens
seedlings. The sulfenylated proteins can be considered for further validation as redox regulators in plants.
Md. Fakruzzaman, Nasser Ghanem, Jae‐Il Bang, A-Na Ha et al.
Endogenous peroxiredoxin II (PRDX II) protein plays a vital role in early embryonic development. This study assessed the beneficial effects of exogenous PRDX II on bovine embryo development at the cellular and molecular levels. To this end, in vitro maturation (IVM) medium was supplemented with vari...
Md. Monirul Islam, Hossain Uddin Shekhar