Recent advances of nucleotide nutrition research in aquaculture: a review

Abstract Although nucleotides ( NT ) have long been implicated as feed attractants in both vertebrate and invertebrate species, research into potential growth and health benefits of dietary NT in aquaculture species has just been implemented in early 2000s. To date, research pertaining to NT supplementation in aquafeed as functional nutrients has shown rather consistent and encouraging, beneficial results in fish and shrimp health management. Dietary NT serve a marked role to enhance growth in early stages of development, improve reproductive performances of brood fish, enhance larval quality, increase stress and disease resistance, modulate immune functions and improve intestinal morphology and gut microbiota of fish and shrimp. NT have also been used as functional supplement in alternative protein based diet,…