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Journal ArticleOpen Access

Prevalence of Toxin Types and Colonization Factors in Enterotoxigenic <i>Escherichia coli</i> Isolated during a 2-Year Period from Diarrheal Patients in Bangladesh

Author Affiliations
International Centre for Diarrhoeal Disease Research, Johns Hopkins University, University of Gothenburg
Published InJournal of Clinical Microbiology
Year2000
Citations202

Abstract

The prevalence of toxin types and colonization factors (CFs) of enterotoxigenic Escherichia coli (ETEC) was prospectively studied with fresh samples (n = 4,662) obtained from a 2% routine surveillance of diarrheal stool samples over 2 years, from September 1996 to August 1998. Stool samples were tested by enzyme-linked immunoassay techniques and with specific monoclonal antibodies for the toxins and CFs. The prevalence of ETEC was 14% (n = 662), with over 70% of the strains isolated from children 0 to 5 years of age, of whom 93% were in the 0- to 3-year-old age range. Of the total ETEC isolates, 49.4% were positive for the heat-stable toxin (ST), 25.4% were positive for the heat-labile toxin (LT) only, and 25.2% were…
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