Journal ArticleOpen Access
Different Expression and Clinical Implications of Cancer-Associated Fibroblast (CAF) Markers in Brain Metastases
Authors
Author Affiliations
Sylhet Agricultural University, Chonnam National University Hwasun Hospital
Published InJournal of Cancer
Year2023
Citations24
Abstract
Our results suggest that high expression of CAF-related biomarkers, particularly PDGFR-β and α-SMA, is associated with poor prognosis and recurrence in patients with BM. With the elucidation of the role and origins of CAF in the tumor microenvironment, CAF can be a new imperative target for BM immunotherapy.
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