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Eosinophilic Gastrointestinal Diseases (EGIDs)

Author Affiliations
University of Colorado Denver, The University of Western Australia, University Malaya Medical Centre, University of Malaya, ...
Published InJournal of Pediatric Gastroenterology and Nutrition
Year2008
Citations65

Abstract

Eosinophilic gastrointestinal diseases (EGIDs) are a heterogeneous group of diseases (eosinophilic esophagitis [EoE], eosinophilic gastroenteritis, and eosinophilic colitis) characterized by gastrointestinal symptoms and increased eosinophils in the intestinal mucosa; more important, other causes of gastrointestinal eosinophilia must have been ruled out for the diagnosis of EGIDs to be confirmed. Original descriptions of EGIDs divided patients into subtypes with respect to the anatomical location affected by eosinophilia; ie, mucosal (diarrhea and bleeding), muscular (obstruction), and serosal (ascites) disease. Recent descriptions characterize the mucosal forms in more detail; patients affected by mucosal EGIDs present with a diverse set of symptoms that reflect the organ-specific section of the intestinal tract that is affected. EoE may present with feeding intolerance, vomiting, food impaction, and…
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