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16+ results
Field: Eosinophilic Esophagitis

Risk of Malignant Progression in Barrett's Esophagus Patients: Results from a Large Population-Based Study

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Seema A. Bhat, Helen G. Coleman, Foad Yousef, B. T. Johnston et al.

Journal: JNCI Journal of the National Cancer Institute
Year: 2011
Citations: 742

BACKGROUND: Barrett's esophagus (BE) is a premalignant lesion that predisposes to esophageal adenocarcinoma. However, the reported incidence of esophageal adenocarcinoma in patients with BE varies widely. We examined the risk of malignant progression in patients with BE using data from the Northern ...

Health SciencesMedicineSurgeryOpen Access
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A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease

Verified

William J. Sandborn, Brian G. Feagan, Stephen B. Hanauer, Herbert Lochs et al.

Journal: GastroenterologyYear: 2002Citations: 683
Life SciencesBiochemistry, Genetics and Molecular BiologyGeneticsOpen Access
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T <sub>H</sub> 2 and T <sub>H</sub> 17 inflammatory pathways are reciprocally regulated in asthma

Verified

David F. Choy, Kevin M. Hart, Lee A. Borthwick, Aarti Shikotra et al.

Journal: Science Translational MedicineYear: 2015Citations: 443

Increasing evidence suggests that asthma is a heterogeneous disorder regulated by distinct molecular mechanisms. In a cross-sectional study of asthmatics of varying severity (n = 51), endobronchial tissue gene expression analysis revealed three major patient clusters: TH2-high, TH17-high, and TH2/17...

Health SciencesMedicinePhysiologyOpen Access
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Epidemiological Features of<i>Helicobacter pylori</i>Infection in Developing Countries

Verified

Pradip Kumar Bardhan

Journal: Clinical Infectious DiseasesYear: 1997Citations: 227

Helicobacter pylori infection has a worldwide distribution, and it has distinct epidemiological features in developing countries. In contrast to that in developed countries, H. pylori infection in developing countries seems to be nearly universal, beginning in early childhood. Children become infect...

Health SciencesMedicineSurgeryOpen Access
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Allergic diseases and asthma

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Ruby Pawankar, Giorgio Walter Canonica, Stephen T. Holgate, Richard F. Lockey

Journal: Current Opinion in Allergy and Clinical ImmunologyYear: 2011Citations: 185

The prevalence of allergic diseases and asthma is increasing worldwide, particularly in low and middle-income countries. Moreover, the complexity and severity of allergic diseases, including asthma, continue to increase especially in children and young adults, who are bearing the greatest burden of ...

Health SciencesMedicinePhysiology
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Long-Term Follow-up of Voluntary Ingestion of <i>Helicobacter pylori</i>

Verified

Arthur J. Morris, Momena Ali, Gordon I. Nicholson, Guillermo I. Perez-Perez et al.

Journal: Annals of Internal MedicineYear: 1991Citations: 179

Brief Reports15 April 1991Long-Term Follow-up of Voluntary Ingestion of Helicobacter pyloriArthur J. Morris, BSc, MBChB, M. Rafiq Ali, MBChB, Gordon I. Nicholson, MBChB, Guillermo I. Perez-Perez, DSc, Martin J. Blaser, MDArthur J. Morris, BSc, MBChB, M. Rafiq Ali, MBChB, Gordon I. Nicholson, MBChB, ...

Health SciencesMedicineSurgery
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THE DIAGNOSIS AND MANAGEMENT OF ANAPHYLAXIS

Verified

Anne K. Ellis, James H. Day

Journal: Journal of Allergy and Clinical ImmunologyYear: 1998Citations: 154

Anaphylaxis is a severe systemic allergic reaction that is potentially fatal. It requires prompt recognition and immediate management. Anaphylaxis has a rapid onset with multiple organ-system involvement and is mostly caused by specific antigens in sensitized individuals. Reactions typically follow ...

Health SciencesMedicineImmunology and AllergyOpen Access
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High prevalence of Helicobacter pylori metronidazole resistance in migrants to east London: relation with previous nitroimidazole exposure and gastroduodenal disease.

Verified

Nick Banatvala, Gareth Davies, Y. Abdi, Louisa Clements et al.

Journal: GutYear: 1994Citations: 113

A high prevalence of metronidazole resistance in Helicobacter pylori is reported in developing countries. This study examined whether migrants referred for diagnostic gastroscopy at a United Kingdom centre (n = 54), had a higher prevalence of metronidazole resistance than subjects born in the United...

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Polymorphisms Near TBX5 and GDF7 Are Associated With Increased Risk for Barrett’s Esophagus

Verified

Claire Palles, Laura Chegwidden, Xinzhong Li, John M. Findlay et al.

Journal: GastroenterologyYear: 2014Citations: 111

BACKGROUND & AIMS: Barrett's esophagus (BE) increases the risk of esophageal adenocarcinoma (EAC). We found the risk to be BE has been associated with single nucleotide polymorphisms (SNPs) on chromosome 6p21 (within the HLA region) and on 16q23, where the closest protein-coding gene is FOXF1. Subse...

Health SciencesMedicineSurgeryOpen Access
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Management of Barrett's Esophagus in the UK: Overtreated and Underbiopsied but Improved by the Introduction of a National Randomized Trial

Verified

Debasish Das, Savid Ishaq, Rebecca Harrison, Kiran Kosuri et al.

Journal: The American Journal of GastroenterologyYear: 2008Citations: 100

OBJECTIVES: To assess the variation in practice of Barrett's esophagus (BE) management in comparison with accepted international guidelines before and after the introduction of a large BE randomized controlled trial (RCT) with protocols including those of tissue sampling. DESIGN: A validated anonymi...

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Helicobacter pylori infection, iron absorption, and gastric acid secretion in Bangladeshi children

Verified

Shafiqul Alam Sarker, Lena Davidsson, Hasan Mahmud, Thomas Walczyk et al.

Journal: American Journal of Clinical NutritionYear: 2004Citations: 97

Background Nonheme-iron absorption requires an acidic milieu. Reduced gastric acid output as a consequence of Helicobacter pylori infection could be an important limiting factor for iron absorption. Objective We measured gastric acid output and iron absorption from a non-water-soluble iron compound ...

Health SciencesMedicineSurgeryOpen Access
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Eosinophilic Gastrointestinal Diseases (EGIDs)

Verified

EGIDs Working Group:, Glenn T. Furuta, David Forbes, Chris Boey et al.

Journal: Journal of Pediatric Gastroenterology and NutritionYear: 2008Citations: 65

Eosinophilic gastrointestinal diseases (EGIDs) are a heterogeneous group of diseases (eosinophilic esophagitis [EoE], eosinophilic gastroenteritis, and eosinophilic colitis) characterized by gastrointestinal symptoms and increased eosinophils in the intestinal mucosa; more important, other causes of...

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<i>Helicobacter pylori</i>and gastric cancer: Indian enigma

Verified

Vatsala Misra

Journal: World Journal of GastroenterologyYear: 2014Citations: 54

Helicobacter pylori (H. pylori) is a gram negative microaerophilic bacterium which resides in the mucous linings of the stomach. It has been implicated in the causation of various gastric disorders including gastric cancer. The geographical distribution and etiology of gastric cancer differ widely i...

Health SciencesMedicineSurgeryOpen Access
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Prevalence ofHelicobacter pylori infection in infants and family contacts in a poor Bangladesh community

Verified

Shafiqul Alam Sarker, MM Rahman, Dilip Mahalanabis, Pradip Kumar Bardhan et al.

Journal: Digestive Diseases and SciencesYear: 1995Citations: 54

Although H. pylori is well established as an etiological agent of type B gastritis and a predisposing factor for peptic ulcer, knowledge about its transmission is unclear. In this study we examined the prevalence of H. pylori infection in the family members of index infants infected with this organi...

Health SciencesMedicineSurgery
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INTRAMURAL ESOPHAGEAL DIVERTICULOSIS AND MONILIASIS

Verified

Rosalind H. Troupin

Journal: American Journal of RoentgenologyYear: 1968Citations: 53

INTRAMURAL ESOPHAGEAL DIVERTICULOSIS AND MONILIASIS A POSSIBLE ASSOCIATIONROSALIND H. TROUPIN, M.D.Audio Available | Share

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