Evaluation of pharmacological activities of methanol extract of Ixora cuneifolia leaves

In the current study in vitro antioxidant, thrombolytic and in vivo analgesic, anti-inflammatory, anti-diarrheal activities of methanol extract of Ixora cuneifolia leaves (MEIL) were investigated. The antioxidant activity was determined by using DPPH free radical scavenging method at doses 25, 50, 100, 200, 400 and 800 μg/ml. Total phenolic content was determined at doses of 50, 100, 150, 200 and 250 μg/ml. Whereas thrombolytic activity was determined by clot lysis method. The analgesic activity was conducted in Swiss albino mice at doses of 250 and 500 mg/kg body weight by hot plate method and acetic acid induced writhing method. Carrageenan induced rat paw edema method was used to evaluate anti-inflammatory activity. For anti-diarrheal activity castor oil induced method was used…