Amita Sharma, Ayub Qadri
Vi capsular polysaccharide (Vi) was first identified as a virulence antigen of Salmonella typhi, the causative agent of typhoid fever in humans; it renders S. typhi resistant to phagocytosis and the action of serum complement. However, the role of Vi during the infection of intestinal epithelium wit...
Md. Fakruddin, Khanjada Shahnewaj Bin Mannan, Stewart Andrews
The viable but nonculturable (VBNC) state is a unique survival strategy of many bacteria in the environment in response to adverse environmental conditions. VBNC bacteria cannot be cultured on routine microbiological media, but they remain viable and retain virulence. The VBNC bacteria can be resusc...
Meera Probha Kabiraz, Priyanka Rani Majumdar, M M Chayan Mahmud, Shuva Bhowmik et al.
Foodborne pathogens are a major public health concern and have a significant economic impact globally. From harvesting to consumption stages, food is generally contaminated by viruses, parasites, and bacteria, which causes foodborne diseases such as hemorrhagic colitis, hemolytic uremic syndrome (HU...
Cesar I. Bin Kingombe, Geert Huys, Mauro Tonolla, M. John Albert et al.
We found 73.1 to 96.9% similarity by aligning the cytolytic enterotoxin gene of Aeromonas hydrophila SSU (AHCYTOEN; GenBank accession no. M84709) against aerolysin genes of Aeromonas spp., suggesting the possibility of selecting common primers. Identities of 90 to 100% were found among the eight sel...
Md. Zahangir Hosain, S. M. Lutful Kabir, MM Kamal
Antimicrobial is an indispensable part of veterinary medicine used for the treatment and control of diseases as well as a growth promoter in livestock production. Frequent use of antimicrobials in veterinary practices may lead to the residue in animal originated products and creates some potential p...
Shah M. Faruque, John J. Mekalanos
Understanding the genetic and ecological factors which support the emergence of new clones of pathogenic bacteria is vital to develop preventive measures. Vibrio cholerae the causative agent of cholera epidemics represents a paradigm for this process in that this organism evolved from environmental ...
Kristen N. LeGault, Stephanie G. Hays, Angus Angermeyer, Amelia C. McKitterick et al.
Back to the future phage The interrelationships that prevail between bacteria and their phage parasites are subtle and evolutionarily dynamic. In Bangladesh, cholera remains endemic, and natural, clinically relevant infections have been monitored for decades. LeGault et al . investigated the relatio...
Kimberley D. Seed, Shah M. Faruque, John J. Mekalanos, Stephen B. Calderwood et al.
The Vibrio cholerae lipopolysaccharide O1 antigen is a major target of bacteriophages and the human immune system and is of critical importance for vaccine design. We used an O1-specific lytic bacteriophage as a tool to probe the capacity of V. cholerae to alter its O1 antigen and identified a novel...
Mohammadali Khan Mirzaei, Md Anik Ashfaq Khan, Prakash Ghosh, Zofia E. Taranu et al.
Stunting, a severe and multigenerational growth impairment, globally affects 22% of children under the age of 5 years. Stunted children have altered gut bacterial communities with higher proportions of Proteobacteria, a phylum with several known human pathogens. Despite the links between an altered ...
Brendan J. O’Hara, Zachary K. Barth, Amelia C. McKitterick, Kimberley D. Seed
Vibrio cholerae-specific bacteriophages are common features of the microbial community during cholera infection in humans. Phages impose strong selective pressure that favors the expansion of phage-resistant strains over their vulnerable counterparts. The mechanisms allowing virulent V. cholerae str...
M. Shaminur Rahman, M. Rafiul Islam, A. S. M. Rubayet Ul Alam, Israt Islam et al.
The emerged novel coronavirus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has created a global health crisis that warrants an accurate and detailed characterization of the rapidly evolving viral genome for understanding its epidemiology, pathogenesis, and containment. Here, we explo...
Kimberley D. Seed, K. Bodi, Andrew M. Kropinski, Hans‐Wolfgang Ackermann et al.
ABSTRACT Lytic bacteriophages are hypothesized to contribute to the seasonality and duration of cholera epidemics in Bangladesh. However, the bacteriophages contributing to this phenomenon have yet to be characterized at a molecular genetic level. In this study, we isolated and sequenced the genomes...
Kimberley D. Seed, Minmin Yen, B. Jesse Shapiro, Isabelle J. Hilaire et al.
The impact of phage predation on bacterial pathogens in the context of human disease is not currently appreciated. Here, we show that predatory interactions of a phage with an important environmentally transmitted pathogen, Vibrio cholerae, can modulate the evolutionary trajectory of this pathogen d...
Supathep Tansirichaiya, Md. Ajijur Rahman, Adam P. Roberts
Abstract Transposable elements in prokaryotes are found in many forms and therefore a robust nomenclature system is needed in order to allow researchers to describe and search for them in publications and databases. Here we provide an update on The Transposon Registry which allocates numbers to any ...
Ananda Tiwari, Sangeet Adhikari, Devrim Kaya, Md. Aminul Islam et al.
Monkeypox disease (MPXD), a viral disease caused by the monkeypox virus (MPXV), is an emerging zoonotic disease endemic in some countries of Central and Western Africa but seldom reported outside the affected region. Since May 2022, MPXD has been reported at least in 74 countries globally, prompting...