Ibrahim A Khalil, Christopher Troeger, Brigette F. Blacker, Puja C Rao et al.
BACKGROUND: Shigella and enterotoxigenic Escherichia coli (ETEC) are bacterial pathogens that are frequently associated with diarrhoeal disease, and are a significant cause of mortality and morbidity worldwide. The Global Burden of Diseases, Injuries, and Risk Factors study 2016 (GBD 2016) is a syst...
Derek Klarin, The VA Million Veteran Program, Scott M. Damrauer, Kelly Cho et al.
The Million Veteran Program (MVP) was established in 2011 as a national research initiative to determine how genetic variation influences the health of US military veterans. Here we genotyped 312,571 MVP participants using a custom biobank array and linked the genetic data to laboratory and clinical...
Samuel A.J. Trammell, Mark S. Schmidt, Benjamin J. Weidemann, Philip Redpath et al.
Abstract Nicotinamide riboside (NR) is in wide use as an NAD + precursor vitamin. Here we determine the time and dose-dependent effects of NR on blood NAD + metabolism in humans. We report that human blood NAD + can rise as much as 2.7-fold with a single oral dose of NR in a pilot study of one indiv...
A. Huq, E. B. Small, P. A. West, Mohsina Huq et al.
Strains of Vibrio cholerae, both O1 and non-O1 serovars, were found to attach to the surfaces of live copepods maintained in natural water samples collected from the Chesapeake Bay and Bangladesh environs. The specificity of attachment of V. cholerae to live copepods was confirmed by scanning electr...
William J. Sandborn, Brian G. Feagan, Stephen B. Hanauer, Herbert Lochs et al.
Sadat Kamal Amit, Md. Mezbah Uddin, Rizwanur Rahman, S. M. Rezwanul Islam et al.
Food preservation involves different food processing steps to maintain food quality at a desired level so that maximum benefits and nutrition values can be achieved. Food preservation methods include growing, harvesting, processing, packaging, and distribution of foods. The key objectives of food pr...
Jason B Harris, Regina C LaRocque, Firdausi Qadri, Edward T Ryan et al.
Cholera is an acute, secretory diarrhoea caused by infection with Vibrio cholerae of the O1 or O139 serogroup. It is endemic in more than 50 countries and also causes large epidemics. Since 1817, seven cholera pandemics have spread from Asia to much of the world. The seventh pandemic began in 1961 a...
G. Balakrish Nair, Thandavarayan Ramamurthy, Sujit Bhattacharya, Basabjit Dutta et al.
Vibrio parahaemolyticus is recognized as a cause of food-borne gastroenteritis, particularly in the Far East, where raw seafood consumption is high. An unusual increase in admissions of V. parahaemolyticus cases was observed at the Infectious Diseases Hospital in Calcutta, a city in the northeastern...
S M Fijul Kabir, Partha Sikdar, Bazle Z. Haque, M. A. Rahman Bhuiyan et al.
Hydrogels based on cellulose comprising many organic biopolymers including cellulose, chitin, and chitosan are the hydrophilic material, which can absorb and retain a huge proportion of water in the interstitial sites of their structures. These polymers feature many amazing properties such as respon...
D. Scott Merrell, Susan M. Butler, Firdausi Qadri, Nadia Dolganov et al.
The factors that enhance the transmission of pathogens during epidemic spread are ill defined. Water-borne spread of the diarrhoeal disease cholera occurs rapidly in nature, whereas infection of human volunteers with bacteria grown in vitro is difficult in the absence of stomach acid buffering. It i...
Sarvajeet Singh Gill, Naser A. Anjum, Mirza Hasanuzzaman, Ritu Gill et al.
Abiotic stresses such as salinity, drought, clilling, heavy metal are the major limiting factors for crop productivity. These stresses induce the overproduction of reactive oxygen species (ROS) which are highly reactive and toxic, which must be minimized to protect the cell from oxidative damage. Th...
Nicola Longo, Cristina Amat Di San Filippo, Marzia Pasquali
Carnitine plays an essential role in the transfer of long-chain fatty acids across the inner mitochondrial membrane. This transfer requires enzymes and transporters that accumulate carnitine within the cell (OCTN2 carnitine transporter), conjugate it with long chain fatty acids (carnitine palmitoyl ...
Jayaseelan Murugaiyan, P. Anand Kumar, G. Srinivasa Rao, Katia Iskandar et al.
Antibiotic resistance, and, in a broader perspective, antimicrobial resistance (AMR), continues to evolve and spread beyond all boundaries. As a result, infectious diseases have become more challenging or even impossible to treat, leading to an increase in morbidity and mortality. Despite the failur...
Harrison Specht, Edward Emmott, Aleksandra A. Petelski, R. Gray Huffman et al.
BACKGROUND: Macrophages are innate immune cells with diverse functional and molecular phenotypes. This diversity is largely unexplored at the level of single-cell proteomes because of the limitations of quantitative single-cell protein analysis. RESULTS: To overcome this limitation, we develop SCoPE...
Zubair Ahmed Ratan, Mohammad Faisal Haidere, Yo Han Hong, Sang Hee Park et al.
Ginseng has been used as a traditional herb in Asian countries for thousands of years. It contains a large number of active ingredients including steroidal saponins, protopanaxadiols, and protopanaxatriols, collectively known as ginsenosides. In the last few decades, the antioxidative and anticancer...