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16+ results
Field: Cellular and Molecular Neuroscience

Purslane Weed (<i>Portulaca oleracea</i>): A Prospective Plant Source of Nutrition, Omega-3 Fatty Acid, and Antioxidant Attributes

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Md. Kamal Uddin, Abdul Shukor Juraimi, Md. Sabir Hossain, Most. Altaf Un Nahar et al.

The Scientific World JOURNAL
Journal:
Year: 2014
Citations: 301

Purslane (Portulaca oleracea L.) is an important plant naturally found as a weed in field crops and lawns. Purslane is widely distributed around the globe and is popular as a potherb in many areas of Europe, Asia, and the Mediterranean region. This plant possesses mucilaginous substances which are o...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Implantable microchip: the futuristic controlled drug delivery system

Verified

Kumar Bishwajit Sutradhar, Chandra Datta Sumi

Journal: Drug DeliveryYear: 2014Citations: 186

There is no doubt that controlled and pulsatile drug delivery system is an important challenge in medicine over the conventional drug delivery system in case of therapeutic efficacy. However, the conventional drug delivery systems often offer a limited by their inability to drug delivery which consi...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety

Verified

Hu‐Jiang Shi, Shuang Wang, Xinping Wang, Rui-Xin Zhang et al.

Journal: Neuroscience BulletinYear: 2023Citations: 128

Anxiety disorders are currently a major psychiatric and social problem, the mechanisms of which have been only partially elucidated. The hippocampus serves as a major target of stress mediators and is closely related to anxiety modulation. Yet so far, its complex anatomy has been a challenge for res...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Biodegradable Implantable Sensors: Materials Design, Fabrication, and Applications

Verified

Nureddin Ashammakhi, Ana López Hernández, Bige Deniz Unluturk, Sergio Quintero et al.

Journal: Advanced Functional MaterialsYear: 2021Citations: 119

Abstract The ability to monitor diseases, therapies, and their effects on the body is a critical component of modern care and personalized medicine. Real time monitoring can be achieved by analyzing body fluids or by applying sensors on, or alternatively, inside the body. Implantable sensors, howeve...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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NMDA Receptor Antagonists: Repositioning of Memantine as a Multitargeting Agent for Alzheimer's Therapy

Verified

Md. Tanvir Kabir, Mohammad Abu Sufian, Md. Sahab Uddin, Mst. Marium Begum et al.

Journal: Current Pharmaceutical DesignYear: 2019Citations: 113

Alzheimer's disease (AD) is a progressive neurodegenerative disease that causes problems with memory, thinking, and behavior. Currently, there is no drug that can reduce the pathological events of this degenerative disease but symptomatic relief is possible that can abate the disease condition. N-me...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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How Many Footsteps Do Dogs Need to Determine the Direction of an Odour Trail?

Verified

Peter G. Hepper, Deborah L. Wells

Journal: Chemical SensesYear: 2005Citations: 106

Dogs have the ability to determine the direction of an odour trail left by a human. This study examined how much olfactory information from this trail is required by dogs to determine direction. Six dogs, able to determine direction, were tested on a 21 footstep trail laid on 21 individual carpet sq...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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Genetic and neuronal mechanisms governing the sex-specific interaction between sleep and sexual behaviors in Drosophila

Verified

Dandan Chen, Divya Sitaraman, Nan Chen, Xin Jin et al.

Journal: Nature CommunicationsYear: 2017Citations: 105

Abstract Animals execute one particular behavior among many others in a context-dependent manner, yet the mechanisms underlying such behavioral choice remain poorly understood. Here we studied how two fundamental behaviors, sex and sleep, interact at genetic and neuronal levels in Drosophila . We sh...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Class II G Protein-Coupled Receptors and Their Ligands in Neuronal Function and Protection

Verified

Bronwen Martin, Rakel López de Maturana, Randall Brenneman, Tom Walent et al.

Journal: NeuroMolecular MedicineYear: 2005Citations: 94

G protein-coupled receptors (GPCRs) play pivotal roles in regulating the function and plasticity of neuronal circuits in the nervous system. Among the myriad of GPCRs expressed in neural cells, class II GPCRs which couples predominantly to the Gs-adenylate cyclase-cAMP signaling pathway, have recent...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Reduced serum BDNF levels are associated with the increased risk for developing MDD: a case–control study with or without antidepressant therapy

Verified

Md. Prova Zaman Emon, Rajesh Das, Nuruna Lovely Nishuty, M. M. A. Shalahuddin Qusar et al.

Journal: BMC Research NotesYear: 2020Citations: 88

OBJECTIVE: We do not have any consistent markers for major depressive disorder (MDD) though various biological factors are involved in the pathophysiology. We aimed to evaluate the serum brain-derived neurotrophic factor (BDNF) levels in MDD patients with or without antidepressant therapy compared t...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Drosulfakinin signaling in fruitless circuitry antagonizes P1 neurons to regulate sexual arousal in Drosophila

Verified

Shun‐Fan Wu, Chao Guo, Huan Zhao, Mengshi Sun et al.

Journal: Nature CommunicationsYear: 2019Citations: 87

Animals perform or terminate particular behaviors by integrating external cues and internal states through neural circuits. Identifying neural substrates and their molecular modulators promoting or inhibiting animal behaviors are key steps to understand how neural circuits control behaviors. Here, w...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Calcitonin gene‐related peptide (<scp>CGRP</scp>): A novel target for Alzheimer's disease

Verified

Yogendra Singh, Gaurav Gupta, Birendra Shrivastava, Rajiv Dahiya et al.

Journal: CNS Neuroscience & TherapeuticsYear: 2017Citations: 87

Summary Alzheimer's disease ( AD ) is leading cause of death among older characterized by neurofibrillary tangles, oxidative stress, progressive neuronal deficits, and increased levels of amyloid‐ β (A β ) peptides. Cholinergic treatment could be the best suitable physiological therapy for AD . Calc...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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Alcohol-predictive cues enhance tolerance to and precipitate "craving" for alcohol in social drinkers.

Verified

Christopher G. McCusker, K A Brown

Journal: Journal of Studies on AlcoholYear: 1990Citations: 87

This study attempts to show that tolerance to alcohol is in large part a "learned" response, precipitated by contextual cues predictive of the unconditional drug effect. It also aims to show that the contextual cues integral to such "environment-dependent" tolerance function to increase motivational...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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THE QUEST FOR THE INHIBITORY NEUROTRANSMITTER IN BOVINE TRACHEAL SMOOTH MUSCLE

Verified

A. R. Cameron, C.F. Johnston, C. T. Kirkpatrick, Melanie C. A. Kirkpatrick

Journal: Quarterly Journal of Experimental PhysiologyYear: 1983Citations: 82

The effect of inhibitory nerve stimulation on the mechanical, membrane potential and membrane conductance responses of isolated bovine tracheal smooth muscle has been studied. Membrane responses were measured in a sucrose-gap apparatus. In order to record inhibitory responses, it was necessary to in...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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Electrode materials for brain–machine interface: A review

Verified

N. J. Wu, Shu Wan, Shi Su, Haizhou Huang et al.

Journal: InfoMatYear: 2021Citations: 81

Abstract Brain–machine interface (BMI) is a device that translates neuronal information into commands, which is capable of controlling external software or hardware, such as a computer or robotic arm. In consequence, the electrodes with desirable electrical and mechanical properties for direct inter...

Life SciencesNeuroscienceCellular and Molecular NeuroscienceOpen Access
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The cue‐responsivity phenomenon in dependent drinkers: ‘personality’ vulnerability and anxiety as intervening variables

Verified

Christopher G. McCusker, K A Brown

Journal: British Journal of AddictionYear: 1991Citations: 77

The cue-responsivity phenomenon to alcohol-associated stimuli in dependent drinkers was examined. In accordance with previous research, significant differences on both physiological and subjective cue-responsivity variables, between dependent and non-dependent drinkers were found. The unique contrib...

Life SciencesNeuroscienceCellular and Molecular Neuroscience
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