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Field: Frailty in Older Adults

Frailty and the Prediction of Negative Health Outcomes: A Meta-Analysis

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Sofie Vermeiren, Roberta Vella-Azzopardi, David Beckwée, Ann-Katrin Habbig et al.

Journal: Journal of the American Medical Directors Association
Year: 2016
Citations: 1031

Introduction Frailty is one of the most important concerns regarding our aging population. Evidence grows that the syndrome is linked to several important health outcomes. A general overview of frailty concepts and a comprehensive meta-analysis of their relation with negative health outcomes still l...

Health SciencesMedicineGeriatrics and Gerontology
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Reference ranges of handgrip strength from 125,462 healthy adults in 21 countries: a prospective urban rural epidemiologic (PURE) study

Verified

Darryl P. Leong, Koon Teo, Sumathy Rangarajan, V. Raman Kutty et al.

Journal: Journal of Cachexia Sarcopenia and MuscleYear: 2016Citations: 290

Abstract Background The measurement of handgrip strength (HGS) has prognostic value with respect to all‐cause mortality, cardiovascular mortality and cardiovascular disease, and is an important part of the evaluation of frailty. Published reference ranges for HGS are mostly derived from Caucasian po...

Health SciencesMedicinePhysiologyOpen Access
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Recovery after critical illness in patients aged 80 years or older: a multi-center prospective observational cohort study

Verified

Daren K. Heyland, Allan Garland, Sean M. Bagshaw, Deborah Cook et al.

Journal: Intensive Care MedicineYear: 2015Citations: 278

Purpose Increasingly, very old patients are admitted to Intensive Care Units (ICUs). The objective of this study was to describe 12-month outcomes of these patients and determine which characteristics are associated with a return to baseline physical function 1 year later. Methods In this prospectiv...

Health SciencesMedicineCritical Care and Intensive Care Medicine
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Ageing and adult health status in eight lower-income countries: the INDEPTH WHO-SAGE collaboration

Verified

Paul Kowal, Kathleen Kahn, Nawi Ng, Nirmala Naidoo et al.

Journal: Global Health ActionYear: 2010Citations: 196

BACKGROUND: Globally, ageing impacts all countries, with a majority of older persons residing in lower- and middle-income countries now and into the future. An understanding of the health and well-being of these ageing populations is important for policy and planning; however, research on ageing and...

Social SciencesHealthHealth disparities and outcomesOpen Access
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The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

Verified

Lisa M Force, Jonathan M Kocarnik, Miranda L May, Kayleigh Bhangdia et al.

Journal: The LancetYear: 2025Citations: 186

Background Cancer is a leading cause of death globally. Accurate cancer burden information is crucial for policy planning, but many countries lack up-to-date cancer surveillance data. To inform global cancer-control efforts, we used the Global Burden of Diseases, Injuries, and Risk Factors Study (GB...

Health SciencesMedicineOncologyOpen Access
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Studies to Reduce Unnecessary Medication Use in Frail Older Adults: A Systematic Review

Verified

Jennifer Tjia, Sarah J. Velten, Carole Parsons, Sruthi Valluri et al.

Journal: Drugs & AgingYear: 2013Citations: 173

Background Overuse of unnecessary medications in frail older adults with limited life expectancy remains an understudied challenge. Objective To identify intervention studies that reduced use of unnecessary medications in frail older adults. A secondary goal was to identify and review studies focusi...

Health SciencesMedicineGeriatrics and Gerontology
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The future incidence, prevalence and costs of stroke in the UK

Verified

Derek King, Raphael Wittenberg, Anita Patel, Zahidul Quayyum et al.

Journal: Age and AgeingYear: 2019Citations: 171

BACKGROUND: we project incidence and prevalence of stroke in the UK and associated costs to society to 2035. We include future costs of health care, social care, unpaid care and lost productivity, drawing on recent estimates that there are almost 1 million people living with stroke and the current c...

Health SciencesMedicineEpidemiologyOpen Access
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Screening for Frailty in Canada’s Health Care System: A Time for Action

Verified

John Muscedere, Melissa K. Andrew, Sean M. Bagshaw, Carole A. Estabrooks et al.

Journal: Canadian Journal on Aging / La Revue canadienne du vieillissementYear: 2016Citations: 116

RÉSUMÉ Avec le vieillissement de la population canadienne, la fragilité – avec son risque accru du déclin fonctionnel, la détérioration de la santé, et le décès – devient de plus en plus répandue. La physiologie de la fragilité reflète son origine parmi organes et systèmes multiples. Environ un quar...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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Mini Nutritional Assessment of rural elderly people in Bangladesh: the impact of demographic, socio-economic and health factors

Verified

Zarina Nahar Kabir, Tamanna Ferdous, Tommy Cederholm, Masuma Akter Khanam et al.

Journal: Public Health NutritionYear: 2006Citations: 93

ObjectiveIn stating the Millennium Development Goals, the United Nations aims to halve malnutrition around the world by 2015. Nutritional status of the elderly population in low-income countries is seldom focused upon. The present study aimed to evaluate the magnitude of malnutrition among an elderl...

Health SciencesMedicinePhysiologyOpen Access
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Associations between frailty trajectories and frailty status and adverse outcomes in community‐dwelling older adults

Verified

Alejandro Álvarez‐Bustos, Jose Antonio Carnicero‐Carreño, Juan Luis Sánchez‐Sánchez, Francisco Javier Garcia‐Garcia et al.

Journal: Journal of Cachexia Sarcopenia and MuscleYear: 2021Citations: 92

BACKGROUND: The association between frailty and adverse outcomes has been clearly defined. Frailty is associated with age, but different frailty evolution patterns might determine the incidence of adverse outcomes at older ages. So far, few observational studies have examined how distinct frailty tr...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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Review and evaluation of performance measures for survival prediction models in external validation settings

Verified

Mohammad Shafiqur Rahman, Gareth Ambler, Babak Choodari‐Oskooei, Rumana Omar

Journal: BMC Medical Research MethodologyYear: 2017Citations: 91

BACKGROUND: When developing a prediction model for survival data it is essential to validate its performance in external validation settings using appropriate performance measures. Although a number of such measures have been proposed, there is only limited guidance regarding their use in the contex...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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Correlation between nutritional status and comprehensive physical performance measures among older adults with undernourishment in residential institutions

Verified

Devinder Kaur Ajit Singh, Zahara Abdul Manaf, Suzana Shahar, Noor Aini Mohd Yusoff et al.

Journal: Clinical Interventions in AgingYear: 2014Citations: 80

PURPOSE: The consequences of combined undernourishment and decreased physical performance in older adults are debilitating and increases cost of care. To date, the information regarding the association between nutritional status and physical performance does not provide a complete picture. Most stud...

Health SciencesMedicinePhysiologyOpen Access
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Role of sarcopenia in the frailty transitions in older adults: a population‐based cohort study

Verified

Alejandro Álvarez‐Bustos, Jose Antonio Carnicero‐Carreño, Betty Davies, Francisco Javier Garcia‐Garcia et al.

Journal: Journal of Cachexia Sarcopenia and MuscleYear: 2022Citations: 74

BACKGROUND: Frailty and sarcopenia are age-associated syndromes that have been associated with the risk of several adverse events, mainly functional decline and death, that usually coexist. However, the potential role of one of them (sarcopenia) in modulating some of those adverse events associated ...

Health SciencesMedicineGeriatrics and GerontologyOpen Access
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Living arrangements, relationship to people in the household and admission to care homes for older people

Verified

Mark McCann, Michael Donnelly, Dermot O’Reilly

Journal: Age and AgeingYear: 2011Citations: 72

OBJECTIVE: to assess the separate contributions of marital status, living arrangements and the presence of children to subsequent admission to a care home. DESIGN AND METHODS: a longitudinal study derived from the health card registration system and linked to the 2001 Census, comprising 28% of the N...

Social SciencesSociology and Political ScienceIntergenerational Family Dynamics and CaregivingOpen Access
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Geriatric Care during Public Health Emergencies: Lessons Learned from Novel Corona Virus Disease (COVID-19) Pandemic

Verified

Hoimonty Mazumder, Md Mahbub Hossain, Anupom Das

Journal: Journal of Gerontological Social WorkYear: 2020Citations: 70

Geriatric care in public health emergencies is a serious concern, while, high case-fatalities among older adults across the globe in COVID-19 pandemic implies lack of preparedness. Most of the countries irrespective of developing and developed one enormously struggling because of an inchoate respons...

Health SciencesMedicineEpidemiology
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