John P. Clancy, Lieven Dupont, Michael W. Konstan, Joanne Billings et al.
RATIONALE: Arikace is a liposomal amikacin preparation for aerosol delivery with potent Pseudomonas aeruginosa killing and prolonged lung deposition. OBJECTIVES: To examine the safety and efficacy of 28 days of once-daily Arikace in cystic fibrosis (CF) patients chronically infected with P aeruginos...
Golam Rabbani, Thomas Butler, Joseph A. Knight, S. C. Sanyal et al.
To evaluate the antisecretory activity of berberine sulfate (BS), we studied 165 adult patients with acute diarrhea due to enterotoxigenic Escherichia coli (ETEC) and Vibrio cholerae in randomized controlled trials. In patients with ETEC diarrhea who received 400 mg of BS in a single oral dose, the ...
Habibul Ahsan, Yu Chen, Muhammad G. Kibriya, Vesna Slavkovich et al.
We conducted a case-control study to investigate interindividual variability in susceptibility to health effects of inorganic arsenic due to arsenic metabolism efficiency, genetic factors, and their interaction. A total of 594 cases of arsenic-induced skin lesions and 1,041 controls was selected fro...
Lesley Bailie, Maurice B. Loughrey, Helen G. Coleman
Background & aims Certain subsets of colorectal serrated polyps (SP) have malignant potential. We performed a systematic review and meta-analysis to investigate the association between modifiable lifestyle factors and risk for SPs. Methods We conducted a systematic search of Medline, Embase, and Web...
Verena Bihrer, Mireen Friedrich‐Rust, Bernd Kronenberger, Nicole Forestier et al.
OBJECTIVES: The liver contains large amounts of microRNA-122 (miR-122), whereas other tissues contain only marginal amounts of this miRNA. MicroRNAs have also been found to circulate in the blood in a cell-free form; their potential as readily accessible disease markers is currently evaluated. Here,...
Hiroto Miwa, Mae F. Go, Nobuhiro Sato
The actual distribution of Helicobacter pylori infection and its related diseases in various Asian countries is controversial. Only limited information is available regarding this issue. We discuss the etiological role of H. pylori in gastric cancer through the Asian experience. Seroprevalence of H....
Neyres Zínia Taveira de Jesus, Heloina de Souza Falcão, Isis Fernandes Gomes, Thiago Jose de Almeida Leite et al.
This review of the current literature aims to study correlations between the chemical structure and gastric anti-ulcer activity of tannins. Tannins are used in medicine primarily because of their astringent properties. These properties are due to the fact that tannins react with the tissue proteins ...
Wasif Ali Khan, Carlos Seas, Ujjwal Dhar, Mohammed Abdus Salam et al.
BACKGROUND: Treatment of shigellosis is currently limited by the high prevalence of multidrug-resistant strains of Shigella. OBJECTIVE: To determine the efficacy of azithromycin in the treatment of shigellosis. DESIGN: Randomized, double-blind clinical trial. SETTING: Diarrhea treatment center in Dh...
Arthur J. Morris, Momena Ali, Gordon I. Nicholson, Guillermo I. Perez-Perez et al.
Brief Reports15 April 1991Long-Term Follow-up of Voluntary Ingestion of Helicobacter pyloriArthur J. Morris, BSc, MBChB, M. Rafiq Ali, MBChB, Gordon I. Nicholson, MBChB, Guillermo I. Perez-Perez, DSc, Martin J. Blaser, MDArthur J. Morris, BSc, MBChB, M. Rafiq Ali, MBChB, Gordon I. Nicholson, MBChB, ...
Livingstone Solomon, Sorsiah Mansor, Peter Mallon, Eilish Donnelly et al.
Golam Rabbani, Telahun Teka, Badiuz Zaman, N. Majid et al.
Background & aims Because of the beneficial intestinal effects of dietary fibers, we have evaluated the therapeutic effects of green banana or pectin in children with persistent diarrhea. Methods In a double-blind trial, 62 boys, age 5-12 months, were randomly given a rice-based diet containing eith...
Mamun Al‐Mahtab, Michel Bazinet, Andrew Vaillant
UNLABELLED: Previous in vivo studies have suggested that nucleic acid polymers (NAPs) may reduce circulating levels of HBsAg in the blood by blocking its release from infected hepatocytes and that this effect may have clinical benefit. NAP treatment, was evaluated in two clinical studies in patients...
Shafiqul Alam Sarker, Thomas Casswall, Dilip Mahalanabis, NUR H. ALAM et al.
BACKGROUND: Oral ingestion of immunoglobulins in humans has been shown to be effective as prophylaxis against enteric infections. However, its therapeutic effect in children with infectious diarrhea has hitherto not been proven. We treated children with rotavirus diarrhea with immunoglobulins extrac...
Robert Y. Chen, Vanderlene L. Kung, Subhasish Das, Md. Shabab Hossain et al.
BACKGROUND: Environmental enteric dysfunction (EED) is an enigmatic disorder of the small intestine that is postulated to play a role in childhood undernutrition, a pressing global health problem. Defining the incidence of this disorder, its pathophysiological features, and its contribution to impai...
Akhirunnesa Mily, Rokeya Sultana Rekha, S. M. Mostafa Kamal, Abu Saleh Mohammad Arifuzzaman et al.
BACKGROUND: Development of new tuberculosis (TB) drugs and alternative treatment strategies are urgently required to control the global spread of TB. Previous results have shown that vitamin D3 (vitD3) and 4-phenyl butyrate (PBA) are potent inducers of the host defense peptide LL-37 that possess ant...