Sachel Mok, Elizabeth A. Ashley, Pedro Eduardo Ferreira, Lei Zhu et al.
Artemisinin resistance in Plasmodium falciparum threatens global efforts to control and eliminate malaria. Polymorphisms in the kelch domain-carrying protein K13 are associated with artemisinin resistance, but the underlying molecular mechanisms are unknown. We analyzed the in vivo transcriptomes of...
M. Habibur Rahman, Kenji Kawai
Mohammad Shafiul Alam, Md Gulam Musawwir Khan, Nurunnabi Chaudhury, Sharmina Deloer et al.
BACKGROUND: Information related to malaria vectors is very limited in Bangladesh. In the changing environment and various Anopheles species may be incriminated and play role in the transmission cycle. This study was designed with an intention to identify anopheline species and possible malaria vecto...
F. Qadri, T R Bhuiyan, K K Dutta, R Raqib et al.
BACKGROUND AND AIMS: The general concept is that as Vibrio cholerae is not invasive, it mediates a non-inflammatory type of infection. This is being re-evaluated based on available data that natural cholera infection or cholera toxin induces a Th2-type of immune profile and stimulates the humoral im...
Alokesh Kumar Ghosh, Sujogya Kumar Panda, Walter Luyten
Disease epidemics in shrimp aquaculture increase apace with the development of aquaculture systems throughout the world. The disease caused by Vibrio spp. (vibriosis) is considered the most devastating, which has made it the most feared bacterial disease in the shrimp sector. In aquaculture, several...
Yuki Fujii, Naoshi Dohmae, Koji Takio, Sarkar M. A. Kawsar et al.
A novel lectin structure was found for a 17-kDa α-D-galactose-binding lectin (termed "MytiLec") isolated from the Mediterranean mussel, Mytilus galloprovincialis. The complete primary structure of the lectin was determined by Edman degradation and mass spectrometric analysis. MytiLec was found to co...
Firdausi Qadri, Mohammad Ali, Julia Lynch, Fahima Chowdhury et al.
BACKGROUND: A single-dose regimen of inactivated whole-cell oral cholera vaccine (OCV) is attractive because it reduces logistical challenges for vaccination and could enable more people to be vaccinated. Previously, we reported the efficacy of a single dose of an OCV vaccine during the 6 months fol...
S.M. Sharifuzzaman, Amany Abbass, John Tinsley, Brian Austin
The efficacy of cellular components of probiotics Kocuria SM1 and Rhodococcus SM2 to protect rainbow trout (Oncorhynchus mykiss, Walbaum) against vibriosis was assessed. Groups of fish (average weight = 10-15 g) were immunized intraperitoneally (i.p.) with 0.1 ml of subcellular materials, i.e., 0.2 ...
Jason B. Harris, Michael J. Podolsky, Taufiqur Rahman Bhuiyan, Fahima Chowdhury et al.
BACKGROUND: Infection with intestinal helminths is common and may contribute to the decreased efficacy of Vibrio cholerae vaccines in endemic compared to non-endemic areas. However, the immunomodulatory effects of concomitant intestinal parasitic infection in cholera patients have not been systemati...
Amany Abbass, S.M. Sharifuzzaman, Brian Austin
Subcellular components of the probiotics Aeromonas sobria GC2 and Bacillus subtilis JB-1, when administered to rainbow trout, Oncorhynchus mykiss, conferred protection against a new biogroup of Yersinia ruckeri. Thus, intraperitoneal or intramuscular injection of rainbow trout with cell wall protein...
Robert C. Kauffman, Taufiqur Rahman Bhuiyan, Rie Nakajima, Leslie M. Mayo-Smith et al.
We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the cholera-induced responses were characterized by high levels...
Lei Zhu, Rob W. van der Pluijm, Michal Kucharski, Sourav Nayak et al.
The emergence and spread of artemisinin-resistant Plasmodium falciparum, first in the Greater Mekong Subregion (GMS), and now in East Africa, is a major threat to global malaria elimination ambitions. To investigate the artemisinin resistance mechanism, transcriptome analysis was conducted of 577 P....
Neaz A. Hasan, Mohammad Mahfujul Haque, Steve Hinchliffe, James Guilder
White Spot Disease (WSD) caused by White Spot Syndrome Virus (WSSV), is responsible for widespread mortality and economic losses across almost the entire Asian shrimp farming industry. The distribution of disease prevalence is however uneven, and is likely dependent on a range of management, environ...
S.M. Sharifuzzaman, Brian Austin
Probiotic Kocuria SM1, which was part of the allochthonous gut microbiota of rainbow trout, was administered to rainbow trout (Oncorhynchus mykiss) fingerlings as dietary supplement at approximately 10(8) cells g(-1) for two weeks. The fish were challenged with Vibrio anguillarum and innate immunity...
Md Hadiuzzaman, Mohammad Moniruzzaman, Md Shahjahan, Sungchul C. Bai et al.
β-glucan is considered as an effective immunostimulant because of its binding capacity to different receptors on leukocytes leading to the stimulation of immune responses including bactericidal activity, cytokine productivity, and survival fit ability at cellular levels. In response to immune cell s...