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Field: Oncology

Metal complexes of sulphur and nitrogen-containing ligands: Complexes of s-benzyldithiocarbazate and a schiff base formed by its condensation with pyridine-2-carboxaldehyde

Verified

M.A. Ali, M.T.H. Tarafdar

Journal: Journal of Inorganic and Nuclear Chemistry
Year: 1977
Citations: 215
Health SciencesMedicineOncology
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A machine learning approach for skin disease detection and classification using image segmentation

Verified

Mostafiz Ahammed, Md. Al Mamun, Mohammad Shorif Uddin

Journal: Healthcare AnalyticsYear: 2022Citations: 211

Skin diseases are common health problems around the world. The perils of the infections are invisible, which cause physical health distress as well as initiate mental depression. In addition, it sometimes leads to skin cancer in severe cases. Subsequently, diagnosing skin diseases from clinical imag...

Health SciencesMedicineOncologyOpen Access
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Black, Asian and Minority Ethnic groups in England are at increased risk of death from COVID-19: indirect standardisation of NHS mortality data

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Robert W Aldridge, Dan Lewer, Srinivasa Vittal Katikireddi, Rohini Mathur et al.

Journal: Wellcome Open ResearchYear: 2020Citations: 210

<ns4:p> <ns4:bold>Background</ns4:bold> : International and UK data suggest that Black, Asian and Minority Ethnic (BAME) groups are at increased risk of infection and death from COVID-19. We aimed to explore the risk of death in minority ethnic groups in England using data reported by NHS England. <...

Health SciencesMedicineOncologyOpen Access
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An Interpretable Skin Cancer Classification Using Optimized Convolutional Neural Network for a Smart Healthcare System

Verified

Krishna Mridha, Md. Mezbah Uddin, Jungpil Shin, Susan Khadka et al.

Journal: IEEE AccessYear: 2023Citations: 206

Skin cancer is a prevalent form of malignancy globally, and its early and accurate diagnosis is critical for patient survival. Clinical evaluation of skin lesions is essential, but it faces challenges such as long waiting times and subjective interpretations. Deep learning techniques have been devel...

Health SciencesMedicineOncologyOpen Access
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Lifestyle Risk Factors for Serrated Colorectal Polyps: A Systematic Review and Meta-analysis

Verified

Lesley Bailie, Maurice B. Loughrey, Helen G. Coleman

Journal: GastroenterologyYear: 2016Citations: 202

Background & aims Certain subsets of colorectal serrated polyps (SP) have malignant potential. We performed a systematic review and meta-analysis to investigate the association between modifiable lifestyle factors and risk for SPs. Methods We conducted a systematic search of Medline, Embase, and Web...

Health SciencesMedicineOncologyOpen Access
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Socio-Economic and Health Access Determinants of Breast and Cervical Cancer Screening in Low-Income Countries: Analysis of the World Health Survey

Verified

Tomi Akinyemiju

Journal: PLoS ONEYear: 2012Citations: 195

BACKGROUND: Breast and Cervical cancer are the two most common cancers among women in developing countries. Regular screening is the most effective way of ensuring that these cancers are detected at early stages; however few studies have assessed factors that predict cancer screening in developing c...

Health SciencesMedicineOncologyOpen Access
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Inhibition of PARP-1 by Olaparib (AZD2281) Increases the Radiosensitivity of a Lung Tumor Xenograft

Verified

Joana M. Senra, Brian A. Telfer, Kim E. Cherry, Cian M. McCrudden et al.

Journal: Molecular Cancer TherapeuticsYear: 2011Citations: 194

PARP-1 is a critical enzyme in the repair of DNA strand breaks. Inhibition of PARP-1 increases the effectiveness of radiation in killing tumor cells. However, although the mechanism(s) are well understood for these radiosensitizing effects in vitro, the underlying mechanism(s) in vivo are less clear...

Health SciencesMedicineOncologyOpen Access
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Beta-Sitosterol: A Promising but Orphan Nutraceutical to Fight Against Cancer

Verified

Muhammad Shahdaat Bin Sayeed, Syeda Sadia Ameen

Journal: Nutrition and CancerYear: 2015Citations: 193

All the currently available cancer therapeutic options are expensive but none of them are safe. However, traditional plant-derived medicines or compounds are relatively safe. One widely known such compound is beta-sitosterol (BS), a plant derived nutrient with anticancer properties against breast ca...

Health SciencesMedicineSurgery
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Metformin in colorectal cancer: molecular mechanism, preclinical and clinical aspects

Verified

Muhamad Noor Alfarizal Kamarudin, Md. Moklesur Rahman Sarker, Jin‐Rong Zhou, Ishwar S. Parhar

Journal: Journal of Experimental & Clinical Cancer ResearchYear: 2019Citations: 192

Growing evidence showed the increased prevalence of cancer incidents, particularly colorectal cancer, among type 2 diabetic mellitus patients. Antidiabetic medications such as, insulin, sulfonylureas, dipeptyl peptidase (DPP) 4 inhibitors and glucose-dependent insulinotropic peptide (GLP-1) analogue...

Life SciencesBiochemistry, Genetics and Molecular BiologyMolecular BiologyOpen Access
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The global, regional, and national burden of cancer, 1990–2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023

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Lisa M Force, Jonathan M Kocarnik, Miranda L May, Kayleigh Bhangdia et al.

Journal: The LancetYear: 2025Citations: 186

Background Cancer is a leading cause of death globally. Accurate cancer burden information is crucial for policy planning, but many countries lack up-to-date cancer surveillance data. To inform global cancer-control efforts, we used the Global Burden of Diseases, Injuries, and Risk Factors Study (GB...

Health SciencesMedicineOncologyOpen Access
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Clinical application and detection techniques of liquid biopsy in gastric cancer

Verified

Shuo Ma, Meiling Zhou, Yanhua Xu, Xinliang Gu et al.

Journal: Molecular CancerYear: 2023Citations: 180

Gastric cancer (GC) is one of the most common tumors worldwide and the leading cause of tumor-related mortality. Endoscopy and serological tumor marker testing are currently the main methods of GC screening, and treatment relies on surgical resection or chemotherapy. However, traditional examination...

Life SciencesBiochemistry, Genetics and Molecular BiologyCancer ResearchOpen Access
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The preparation, characterization, crystal structure and biological activities of some copper(II) complexes of the 2-benzoylpyridine Schiff bases of S-methyl- and S-benzyldithiocarbazate

Verified

Mir Ezharul Hossain, Mohammad Nurul Alam, Jaripa Begum, Mohammad Akbar Ali et al.

Journal: Inorganica Chimica ActaYear: 1996Citations: 180
Health SciencesMedicineOncology
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Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness

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Enza Lonardo, Javier Frias-Aldeguer, Patrick Hermann, Christopher Heeschen

Journal: Cell CycleYear: 2012Citations: 178

Chronic pancreatitis and pancreatic ductal adenocarcinoma (PDAC) are characterized by extensive fibrosis. Importantly, in PDAC, this results in poor vascularization and impaired drug delivery to the cancer cells. Therefore, the combined targeting of pancreatic tumor stroma and chemotherapy should en...

Health SciencesMedicineOncologyOpen Access
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Functional Heterogeneity of Cancer-Associated Fibroblasts from Human Colon Tumors Shows Specific Prognostic Gene Expression Signature

Verified

Mercedes Herrera, Abul Bashar Mir Md. Khademul Islam, Alberto Herrera, Paloma Martín et al.

Journal: Clinical Cancer ResearchYear: 2013Citations: 175

PURPOSE: Cancer-associated fibroblasts (CAF) actively participate in reciprocal communication with tumor cells and with other cell types in the microenvironment, contributing to a tumor-permissive neighborhood and promoting tumor progression. The aim of this study is the characterization of how CAFs...

Health SciencesMedicineOncologyOpen Access
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Randomized phase II study of two schedules of topotecan in previously treated patients with ovarian cancer: a National Cancer Institute of Canada Clinical Trials Group study.

Verified

Paul Hoskins, Elizabeth A. Eisenhauer, Sandra Beare, Manas Pratim Roy et al.

Journal: Journal of Clinical OncologyYear: 1998Citations: 172

PURPOSE: As topotecan is S-phase-specific, its efficacy is likely schedule-dependent. Therefore, a randomized study using a "pick the winner" design was undertaken to compare two schedules in patients with recurrent ovarian cancer. PATIENTS AND METHODS: Patients with recurrent epithelial ovarian can...

Health SciencesMedicineReproductive Medicine
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