A. Grant, A Avenell, Marion Campbell, Andrew M. McDonald et al.
Background Elderly people who have a fracture are at high risk of another. Vitamin D and calcium supplements are often recommended for fracture prevention. We aimed to assess whether vitamin D3 and calcium, either alone or in combination, were effective in prevention of secondary fractures. Methods ...
Nurshad Ali
The outbreak of COVID-19 has created a global public health crisis. Little is known about the protective factors of this infection. Therefore, preventive health measures that can reduce the risk of infection, progression and severity are desperately needed. This review discussed the possible roles o...
Peter Timms
BACKGROUND: Vitamin-D deficiency and vitamin-D receptor genotype (VDR) are risk factors for several disorders with inflammatory components, including coronary heart disease (CHD) and diabetes, though the mechanisms involved are unclear. AIM: To examine the hypothesis that vitamin D status modulates ...
B Ogunkolade, Barbara J. Boucher, Jean M. Prahl, Stephen A. Bustin et al.
Associations have been reported between vitamin D receptor (VDR) gene polymorphisms, type 1 diabetes, insulin secretion, and the insulin resistance syndrome. As VDR polymorphisms have no known functional significance, these findings may implicate a variant of the VDR gene or a locus in linkage diseq...
Daniel Roth, Shaun K. Morris, Stanley Zlotkin, Alison D. Gernand et al.
BACKGROUND: It is unclear whether maternal vitamin D supplementation during pregnancy and lactation improves fetal and infant growth in regions where vitamin D deficiency is common. METHODS: We conducted a randomized, double-blind, placebo-controlled trial in Bangladesh to assess the effects of week...
Wade Johannessen, Dawn M. Elliott
STUDY DESIGN: The biphasic compressive material properties of normal and degenerate human nucleus pulposus tissue were measured in confined compression. OBJECTIVES: The objective of this study was to determine the effects of degeneration and age on the mechanical properties of human nucleus pulposus...
Neel Sengupta, Christopher Yau, Anuratha Sakthianandeswaren, Dmitri Mouradov et al.
BACKGROUND: Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features. METHODS: We characterized the clinicopathological features of BAN CRCs and interrogated their ge...
Vaishali Aggarwal, Hardeep Singh Tuli, Mousumi Tania, Saumya Srivastava et al.
Epigallocatechin gallate (EGCG), also known as epigallocatechin-3-gallate, is an ester of epigallocatechin and gallic acid. EGCG, abundantly found in tea, is a polyphenolic flavonoid that has the potential to affect human health and disease. EGCG interacts with various recognized cellular targets an...
Helen E. Gruber, Tracy Johnson, Kelly Leslie, Jane A. Ingram et al.
STUDY DESIGN: Work presented here used a small animal model to illustrate the feasibility of autologous disc cell implantation. OBJECTIVES: To develop a small animal model for autologous disc cell implantation. SUMMARY OF THE BACKGROUND DATA: The use of autologous disc cells in the potential treatme...
Mahbubul H. Siddiqee, Badhan Bhattacharjee, Umme Ruman Siddiqi, Mohammad Meshbahur Rahman
Abstract Background Vitamin-D deficiency is linked to a wide range of chronic and infectious diseases. Body of literature suggested that the prevalence of this deficiency can have geographical variation. Although vitamin D deficiency is frequently reported in the South Asian population, the scarcity...
Roth DE, Rashed Shah, Black Re, A. H. Baqui
AIM: Acute lower respiratory tract infection (ALRI) is the most important global cause of childhood death. Micronutrient deficiencies may increase the risk of ALRI. A case-control study was conducted to assess the association between vitamin D status and ALRI in rural Bangladesh. METHODS: Children a...
Dongliang Wang, Sheng‐Dan Jiang, Li‐Yang Dai
STUDY DESIGN: This study attempts to determine the biologic response of the intervertebral disc to static and dynamic compression in vitro. OBJECTIVE: To quantitate and compare the changes of histology, Type I and II collagens, aggrecan, interleukin (IL)-1beta, and tumor necrosis factor (TNF)-alpha ...
G Dean, Marta Elian
OBJECTIVES: Previous studies have shown that multiple sclerosis is very uncommon among Indian and Pakistani immigrants to England but that their children born in the United Kingdom, in the age groups available for study, have a similar risk of developing the disease as occurs in the general British ...
Akhirunnesa Mily, Rokeya Sultana Rekha, S. M. Mostafa Kamal, Abu Saleh Mohammad Arifuzzaman et al.
BACKGROUND: Development of new tuberculosis (TB) drugs and alternative treatment strategies are urgently required to control the global spread of TB. Previous results have shown that vitamin D3 (vitD3) and 4-phenyl butyrate (PBA) are potent inducers of the host defense peptide LL-37 that possess ant...
Dawn M. Elliott, Joseph J. Sarver
STUDY DESIGN: Measure the mechanical properties of the mouse and rat disc in compression and torsion. OBJECTIVES: Validate mouse and rat disc as a biomechanical model of the human disc by comparing the normalized properties in compression and torsion loading. SUMMARY OF BACKGROUND DATA: Rodents have...