Catherine Williamson, Victoria Geenes
In Brief Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic c...
Ibne Karin M. Ali, Mohammad Bakhtiar Hossain, Shantanu Roy, Patrick F. Ayeh‐Kumi et al.
Entamoeba moshkovskii cysts are morphologically indistinguishable from those of the disease-causing species E. histolytica and the nonpathogenic E. dispar. Although sporadic cases of human infection with E. moshkovskii have been reported, the organism is considered primarily a free-living amoeba. No...
Rashidul Haque, Dinesh Mondal, Priya Duggal, Mamun Kabir et al.
The contribution of amebiasis to the burden of diarrheal disease in children and the degree to which immunity is acquired from natural infection were assessed in a 4-year prospective observational study of 289 preschool children in an urban slum in Dhaka, Bangladesh. Entamoeba histolytica infection ...
Rashidul Haque, Priya Duggal, Ibnekarim M. Ali, Mohammad Bakthiar Hossain et al.
Entamoeba histolytica infection and colitis occurred in 55% and 4%, respectively, of a cohort of Bangladeshi preschool children observed for 2 years. DNA typing demonstrated that infecting E. histolytica isolates were genetically diverse. Innate resistance to infection in children was linked to the ...
Elisabeth M. G. de Vries, Manon de Krijger, Martti Färkkilâ, Johanna Arola et al.
Histologic scoring systems specific for primary sclerosing cholangitis (PSC) are not validated. We recently determined the applicability and prognostic value of three histological scoring systems in a single PSC cohort. The aim of this study was to validate their prognostic use and reproducibility a...
James B. Gibson, G W Johnston, T T Fulton, H W Rodgers
Journal Article Extrahepatic portal-venous obstruction Get access J B Gibson, J B Gibson The Liver Clinic, Queen's University, and The Royal Victoria Hospital, Belfast Present address: The Department of Pathology, The University of Hong Kong Search for other works by this author on: Oxford Academic ...
Jessica Tarleton, Rashidul Haque, Dinesh Mondal, Jianfen Shu et al.
Cognitive function was assessed in 191 Bangladeshi children 6-9 years of age using verbal and nonverbal tests. These scores were added to a health surveillance database that was compiled over the four previous years that includes incidence of diarrhea and Entamoeba histolytica infection and nutritio...
Tricia L. Royer, Carol A. Gilchrist, Mamun Kabir, Tuhinur Arju et al.
: TO THE EDITOR: Diarrheal diseases have a major effect on global health, particularly the health of malnourished children (1). The enteric parasites Entamoeba histolytica and E. moshkovskii are potential causes of diarrheal disease in children (2). For the past 20 years, we have been studying Entam...
Sara von Bahr, Ingemar Björkhem, Ferdinand van’t Hooft, Gunvor Alvélius et al.
Mutations in the sterol 27-hydroxylase gene (CYP27A1) cause the disease cerebrotendinous xanthomatosis (CTX) characterized by accumulation of cholesterol and cholestanol in tendons, brain and other tissues (1). In the absence of adequate sterol 27-hydroxylase, the normal oxidation of the steroid sid...
Md. Tozammel Hoque, Susan P.C. Cole
Multidrug resistance protein 4 (MRP4; ABCC4) is a member of the ATP-binding cassette superfamily of membrane transport proteins and confers resistance to nucleoside and nucleotide analogues as well as camptothecin derivatives. MRP4 also mediates the transmembrane transport of several eicosanoids, co...
Rachel Emma Clarke Smith, D. Kolyn, R F Pace
Outpatient Laparoscopic Cholecystectomy was attempted in 98 patients selected from 266 patients presenting for elective cholecystectomy (37%). Two patients required admission following conversion to "open" Cholecystectomy, one patient was admitted for observation because of a technically difficult L...
Floris J.M. Roos, Haoyu Wu, Jorke Willemse, Ruby Lieshout et al.
The well-established 3D organoid culture method enabled efficient expansion of cholangiocyte-like cells from intrahepatic (IHBD) and extrahepatic bile duct (EHBD) tissue biopsies. The extensive expansion capacity of these organoids enables various applications, from cholangiocyte disease modelling t...
Anne CC Lee, Lian V. Folger, Mahmoodur Rahman, Salahuddin Ahmed et al.
BACKGROUND: Severe neonatal hyperbilirubinemia (>20 mg/dL) affects ∼1 million infants annually. Improved jaundice screening in low-income countries is needed to prevent bilirubin encephalopathy and mortality. METHODS: The Bili-ruler is an icterometer for the assessment of neonatal jaundice th...
Conor Doherty, Samir K. Saha, W. A. M. Cutting
Typhoid fever remains a significant public health problem in Southern Asia, particularly with the emergence of multi-resistant strains of Salmonella typhi in the late 1980s. Use of ciprofloxacin in children, although discouraged, is increasing and we aimed to assess whether its use affects growth or...
Choudhury Habibur Rasul, Md Abul Hasan, Farhana Yasmin
BACKGROUND: Kernicterus occurs in infants around the world. This study examined the outcomes of various treatments for neonatal hyperbilirubinemia (NH) used in the Khulna Medical College Hospital in Bangladesh. METHODS: All of the jaundiced newborns in the neonatal ward between 2005 and 2008 were in...